Showing 205–216 of 226 results
Ligand-induced receptor dimerization is the first functional step in receptor activation, representing the most proximal, functional read-out for receptor activation.…
Read MoreThe pattern of intracellular signaling downstream of GPCR activation is now known to be specific to the ligand-receptor pair as…
Read MoreDenosumab (Prolia®) is a fully human sequence derived monoclonal antibody used for the treatment of osteoporosis in menopausal women via…
Read MoreNeutralizing antibodies (NAbs) to biological drugs may cause loss of therapeutic efficacy and in some cases, loss of endogenous protein…
Read MoreSuccess of ADCC assays is highly dependent on the quality of effector cells used. However, human primary cells (such as…
Read MoreListen to the US PEGS 2023 conference talk by Venkatesh Chari, Ph.D. on MOA-reflective, functional cell-based assays (cell lines and…
Watch NowGaurav Agrawal, Ph.D. Scientific Development Manager Abstract Millions of deaths worldwide have been attributed to COVID-19, caused by the SARS-CoV-2…
Read MoreAlpana Prasad, Ph.D. Director, Innovations and Strategic Partnership
Read MoreDiscoveRx has developed a unique assay technology based on an enzyme-coupled detection system that measures ADP accumulation which has been…
Read MoreAssays that directly detect compound binding inside cells can be of great utility in translating in vitro data to more…
Read MoreHere we show how PathHunter GPCR Internalization assays can be used to differentiate between strongly internalizing and weakly internalizing agonist…
Read MoreGaurav Agrawal, Ph.D.Scientific Development Manager Discover how cell-based assays and translational services accelerate cytokine-based immunotherapeutic development from early discovery to…
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