Search results: “AR”

Simple, non-radioactive, & dye-free cytotoxicity assays to specifically measure target cell death

Kit & reagents for sensitive quantification of biologics or small molecules to provide accurate pharmacology & reproducible results

Assays, cell lines, membrane preps, kits, & reagents for small molecule and biologics discovery through commercial release

Recombinant proteins & cell-based assays to identify small molecule inhibitors & modifiers of methyltransferases & bromodomains

Ready-to-use kits for early discovery phases for screening, proof-of-concept, MOA confirmation, or rank-ordering studies

Cell-based assays to measure 2nd messengers (cAMP & calcium), β-arrestin recruitment, receptor internalization, & ligand binding for GPCR targets-based drug…

Fluorescent assays to measure calcium mobilization in cell lines as a direct indication of GPCR or ion channel activation or…

Accurately monitor GPCR activation by biologics or small molecules & detect cellular cAMP production levels for a variety of applications

Non-imaging, cell-based internalization assays for screening & identifying safer drugs for GPCRs

Universal G-protein independent cell-based assays to quantify GPCR activation based on the recruitment of β-arrestin

Directly measure cellular cGMP when studying cGMP-dependent phosphodiesterases & cGMP signaling receptors

High-quality Ion Channel Products for Target Discovery, Hit Screening, Lead Optimization, & Safety Studies