Search results: “Activi”

Directly measure cellular cGMP when studying cGMP-dependent phosphodiesterases & cGMP signaling receptors

Ready-to-use, cell-based bioassay kits to measure direct cell death for screening, characterization, & potency testing

Single donor-derived human primary cells to drive robust & reproducible ADCC & T-cell redirection

Enzymes & cell-based functional, binding, & activity assays for kinase targets discovery through development & for QC lot-release testing

Purified GPCR & ion channel membrane preps for binding & functional analysis

Assays to interrogate the MOA of GLP-1, GIP, and GCG receptors targeting therapeutics to accelerate obesity and type-2 diabetes drug…

Functional & activity assays to analyze receptor dimerization, phosphorylation, internalization, & SH2-recruitment of RTKs & CTK/cytokine receptors

Over 500 high-quality & purified recombinant kinases, phosphatases, & epigenetic & ubiquitin proteins

Interrogate a variety of popular target-specific signaling pathways with cell-based assays

Simple, orthogonal reporter-based assays for screening & understanding therapeutic MOAs

Cell-based assays to confirm compound cell entry, protein target binding, screen & rank inhibitors, & measure cellular potencies

Rapid cell-based assays for detecting protein turnover induced by targeted degrader molecules, such as PROTACs