Search results: “KIT”

Recombinant proteins & cell-based assays to identify small molecule inhibitors & modifiers of methyltransferases & bromodomains

Ready-to-use kits for early discovery phases for screening, proof-of-concept, MOA confirmation, or rank-ordering studies

Cell-based assays to measure 2nd messengers (cAMP & calcium), β-arrestin recruitment, receptor internalization, & ligand binding for GPCR targets-based drug…

Fluorescent assays to measure calcium mobilization in cell lines as a direct indication of GPCR or ion channel activation or…

Accurately monitor GPCR activation by biologics or small molecules & detect cellular cAMP production levels for a variety of applications

Non-imaging, cell-based internalization assays for screening & identifying safer drugs for GPCRs

Universal G-protein independent cell-based assays to quantify GPCR activation based on the recruitment of β-arrestin

Directly measure cellular cGMP when studying cGMP-dependent phosphodiesterases & cGMP signaling receptors

Ready-to-use, cell-based bioassay kits to measure direct cell death for screening, characterization, & potency testing

Enzymes & cell-based functional, binding, & activity assays for kinase targets discovery through development & for QC lot-release testing

Cell-based assays to evaluate activation & translocation of nuclear proteins including nuclear hormone receptors

Assays to interrogate the MOA of GLP-1, GIP, and GCG receptors targeting therapeutics to accelerate obesity and type-2 diabetes drug…