Search results: “RELA”

Accurately monitor GPCR activation by biologics or small molecules & detect cellular cAMP production levels for a variety of applications

Universal G-protein independent cell-based assays to quantify GPCR activation based on the recruitment of β-arrestin

Directly measure cellular cGMP when studying cGMP-dependent phosphodiesterases & cGMP signaling receptors

High-quality Ion Channel Products for Target Discovery, Hit Screening, Lead Optimization, & Safety Studies

Ready-to-use, cell-based bioassay kits to measure direct cell death for screening, characterization, & potency testing

Single donor-derived human primary cells to drive robust & reproducible ADCC & T-cell redirection

Cell-based assays to evaluate activation & translocation of nuclear proteins including nuclear hormone receptors

Assays to interrogate the MOA of GLP-1, GIP, and GCG receptors targeting therapeutics to accelerate obesity and type-2 diabetes drug…

Quantitative cell-based assays to identify pharmacochaperones that stabilize & correct disease-relevant mutant GPCRs, ion channels, or transporters

Providing functional, MOA-based bioassays with superior lot-to-lot reproducibility & potency testing

Interrogate a variety of popular target-specific signaling pathways with cell-based assays

Cell-based assays to confirm compound cell entry, protein target binding, screen & rank inhibitors, & measure cellular potencies