Search results: “Ret”

Directly measure cellular cGMP when studying cGMP-dependent phosphodiesterases & cGMP signaling receptors

Single donor-derived human primary cells to drive robust & reproducible ADCC & T-cell redirection

Enzymes & cell-based functional, binding, & activity assays for kinase targets discovery through development & for QC lot-release testing

Cell-based assays to evaluate activation & translocation of nuclear proteins including nuclear hormone receptors

Assays to interrogate the MOA of GLP-1, GIP, and GCG receptors targeting therapeutics to accelerate obesity and type-2 diabetes drug…

Quantitative cell-based assays to identify pharmacochaperones that stabilize & correct disease-relevant mutant GPCRs, ion channels, or transporters

Functional & activity assays to analyze receptor dimerization, phosphorylation, internalization, & SH2-recruitment of RTKs & CTK/cytokine receptors

Over 500 high-quality & purified recombinant kinases, phosphatases, & epigenetic & ubiquitin proteins

Interrogate a variety of popular target-specific signaling pathways with cell-based assays

Complete set of parental cell lines, vectors, kits, & retroparticles to build your own stable cell lines & cell-based assays

Screening cell-based translocation assays for analyzing the movement of proteins to multiple membrane compartments within the cell

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