Search results: “Ros”

Universal G-protein independent cell-based assays to quantify GPCR activation based on the recruitment of β-arrestin

High-quality Ion Channel Products for Target Discovery, Hit Screening, Lead Optimization, & Safety Studies

Enzymes & cell-based functional, binding, & activity assays for kinase targets discovery through development & for QC lot-release testing

Assays to interrogate the MOA of GLP-1, GIP, and GCG receptors targeting therapeutics to accelerate obesity and type-2 diabetes drug…

Quantitative cell-based assays to identify pharmacochaperones that stabilize & correct disease-relevant mutant GPCRs, ion channels, or transporters

Functional & activity assays to analyze receptor dimerization, phosphorylation, internalization, & SH2-recruitment of RTKs & CTK/cytokine receptors

Over 500 high-quality & purified recombinant kinases, phosphatases, & epigenetic & ubiquitin proteins

Interrogate a variety of popular target-specific signaling pathways with cell-based assays

Cell-based assays to confirm compound cell entry, protein target binding, screen & rank inhibitors, & measure cellular potencies

Rapid cell-based assays for detecting protein turnover induced by targeted degrader molecules, such as PROTACs

Complete set of parental cell lines, vectors, kits, & retroparticles to build your own stable cell lines & cell-based assays

Screening cell-based translocation assays for analyzing the movement of proteins to multiple membrane compartments within the cell