Most therapeutic antibodies have a Fab’ region that binds the antigen, and an Fc region which binds to and activates…
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The development of new medicines for treating diseases and new chemical probes for elucidating biological function continues to rely on…
Read MoreInformation on compound-target engagement obtained from traditional in vitro binding assays differs greatly from that in a physiologically relevant model…
Read MoreWhether you’re looking to screen a library of drug candidates for binding to a particular target protein, checking drug cell…
Read MoreThe COVID-19 pandemic has left us racing against time for remediation. As a result, we have witnessed hundreds of therapeutic…
Read MoreGlucagon-Like Peptide-1 (GLP-1), a member of the glucagon-secretin peptide family, is secreted from L-cells of the small intestine and binds…
Read MoreA novel and growing modality in drug discovery has been the application of Targeted Protein Degradation (TPD). TPD involves the…
Read MoreAndrew Green Sr. Business Development Manager
Read MoreLearn about the first commercially available SIRPα/CD47 cell-based assay — PathHunter SIRPα Signaling Assay. Find out more about the generation…
Watch NowLearn how InCELL cell-based binding assays can be used to detect compound cell entry and engagement to specific targets including…
Watch NowLearn how to easily detect target protein turnover induced by targeted degrader molecules, such as PROTACs (trademark of Arvinas). Discover…
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