Showing 13–24 of 45 results
Learn about the first commercially available SIRPα/CD47 cell-based assay — PathHunter SIRPα Signaling Assay. Find out more about the generation…
Watch NowHistone modifications are essential in eukaryotic gene expression and regulation, and are driven by histone writer, eraser, and reader proteins.…
Read MoreWith the drug industry’s expanding emphasis on biologics, the need for robust cell-based assays has grown at all stages of…
Read MoreProtein kinases are critical to many cellular pathways and play a role in several therapeutic areas such as oncology, inflammation,…
Watch NowDiscoveRx has developed a panel of over 120 characterized GPCR cell lines that monitor receptor activity using interaction with human…
Read MoreDrug efficacy and cellular target engagement studies have traditionally been monitored by evaluation of downstream cellular responses, such as detection…
Read MoreFollowing the recent regulatory approvals of a number of checkpoint inhibitor therapeutics, development of a wide array of immunomodulatory therapeutic…
Read MoreOne of the major bottlenecks in the development of biosimilars is the need for good bioassays to create potency, stability…
Read MoreCell-based bioassays often pose a hurdle during a rapidly moving biologics development program. High standards for assay accuracy, precision, reproducibility…
Read MoreLigand-induced receptor dimerization is an early functional step in receptor activation, representing the most proximal, functional read-out for Interleukin receptors.…
Read MoreThe clinical success of an ever-increasing array of biologics has led to the development of a wide spectrum of immunomodulatory…
Read MoreOrphan GPCRs continue to represent a target class with immense potential for the discovery of novel therapeutic compounds. In spite…
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