Search results: “Rse”

Showing 13–22 of 22 results

Scientific Posters Ligand Characterization of Mas-Related GPCR-X2 via Cell-Based Assays: Implications in Safety Liability Tests

Mast cells are principal players in IgE-, and more recently, non-IgE-mediated anaphylactoid reactions or pseudo-allergic Adverse Drug Reactions (ADR). A…

Scientific Posters Measuring Receptor Dimerization To Create Functional Cell-Based Assays for ~85% of the Interleukin Receptor Family

Ligand-induced receptor dimerization is the first functional step in receptor activation, representing the most proximal, functional read-out for receptor activation.…

Scientific Posters Detection of Cytokine and Growth Factor Receptor Dimerization Using Enzyme Fragment Complementation

Ligand-induced receptor dimerization is the first functional step in receptor activation, representing the most proximal, functional read-out for receptor activation.…

Scientific Posters Detection of EGFR, HER2, HER3 and HER4 Hetero- and Homodimerization Using EFC-based Cellular Assays

Ligand-induced receptor dimerization is the first functional step in receptor activation, representing the most proximal, functional read-out for receptor activation.…

Scientific Posters Development of Simple, Robust Bioassays for Biosimilar & Biobetter Development

One of the major bottlenecks in the development of biosimilars is the need for good bioassays to create potency, stability…

Scientific Posters CAR-T Cell Screening in Tumor Spheroids Using Corning Spheroid Microplates

Chimeric antigen receptor (CAR)-T cells, which are engineered to recognize target cell surface antigens expressed on tumor cells, have shown…

Scientific Posters Building Robust and Simple Cell-Based Assays for Interleukins and Their Receptors

Ligand-induced receptor dimerization is an early functional step in receptor activation, representing the most proximal, functional readout for Interleukin receptors.…

Scientific Posters Building Better Cell-Based Assays for Interleukins and Their Receptors

Ligand-induced receptor dimerization is an early functional step in receptor activation, representing the most proximal, functional read-out for Interleukin receptors.…

Videos Accelerating Immuno-Oncology Drug Discovery with MOA-Reflective, Functional Cell-Based Assays

Listen to the US PEGS 2023 conference talk by Venkatesh Chari, Ph.D. on MOA-reflective, functional cell-based assays (cell lines and…

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Brochures & Flyers InCELL Pulse™ Target Engagement Kinase Reference Set

View validation data for diverse kinases. Cellular target engagement potency data for multiple kinase inhibitors Dose response curves for under-studied…