Striatal-enriched protein tyrosine phosphatase (STEP) is a brain-specific enzyme that regulates the signaling molecules that control synaptic plasticity and neuronal…
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The MAS-related Gq protein-coupled receptor X4 (MRGPRX4) is poorly investigated. MRGPRX4 has been proposed to be involved in pain transmission,…
Read MoreAgonistic Antibodies and the Role of Checkpoint Receptors in Immune Function
Read MoreWatch this webinar to discover qualified bioassays assessing therapeutic antibody mechanisms, case studies about agonistic effects in antibodies initially deemed…
Watch NowThe clinical success of an ever-increasing array of biologics has led to the development of a wide spectrum of immunomodulatory…
Read MoreExplore GPCR-Ligand Interactions & Signaling Pathways with Binding & Functional Assays
Read MoreBromodomain protein 4 (BRD4), a member of the bromodomain and extra-terminal (BET) proteinfamily, acts as a central element in transcriptional…
Read MoreRegulatory T cells (Tregs) are indispensable for maintaining self-tolerance by suppressing conventional T cells. On the other hand, Tregs promote…
Read MoreInformation on compound-target engagement obtained from traditional in vitro binding assays differs greatly from that in a physiologically relevant model…
Read MoreImportance in Drug Discovery & Development for Quality Testing Programs. GPCR CNR1 Bioassay example.
Read MoreEurofins DiscoverX, in conjunction with Drug Target Review, sponsored and moderated a Bioassay roundtable discussion webinar with group leaders from…
Read MoreAndrew Green Sr. Business Development Manager
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