Learn how KILR CD16 effector cells ensure assay reproducibility with higher signal-to-background ratios, without worrying about donor variability. PBMC effector…
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Learn how functional cell-based assays support COVID-19 drug discovery programs, particularly in managing proinflammatory cytokines associated with high mortality rate…
Watch NowThere are at least three unique features of allosteric ligand-receptor interactions that lead to potentially valuable therapeutic behaviors…
Read MoreTherapeutic regulators require assay data on the impact of Fc effector-mediated function of antibodies during their development as therapeutics. The…
Read MoreIt is well established that ligand binding can protect proteins from thermal denaturation in a cellular milieu; however, the broad…
Watch NowWith the drug industry’s expanding emphasis on biologics, the need for robust cell-based assays has grown at all stages of…
Read MoreImmune checkpoint receptors play a key role in maintaining antitumor immunity, avert immunopathology, and modulate overall immune homeostasis. However, cancer…
Read MorePBMC effector cells have inherent donor variability, reducing their consistency and reproducibility in lot release assays. Antibody-Dependent Cell Cytotoxicity (ADCC)…
Watch NowThe screening and functional characterization of novel ligands for G-Protein Coupled Receptors (GPCR) remains a key focus in drug discovery.…
Watch NowCOVID-19 has been declared a global pandemic by WHO. The disease is transmitted when the SARS-CoV-2 virus infects the respiratory…
Watch NowA quantitative and robust bioassay that is reflective of the MOA of the drug is a critical component of any…
Watch NowThe webinar focusses on measuring antibody-mediated cell death using DiscoverX’s KILR Bioassays, and how they can be used to measure…
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