Search results: “IR”

Interleukins are known for their involvement in functioning of both the adaptive and innate immune systems. Interleukins direct immune cells…

Cell-based bioassays often pose a hurdle during a rapidly moving biologics development program. High standards for assay accuracy, precision, reproducibility…

Cell-based bioassays often pose a hurdle during a rapidly moving biologics development program. High standards for assay accuracy, precision, reproducibility…

One of the major bottlenecks in the development of biosimilars is the need for good bioassays to create potency, stability…

Cell-based bioassays often pose a hurdle during a rapidly moving biologics development program. High standards for assay accuracy, precision, reproducibility…

The clinical success of an ever-increasing array of biologics has led to the development of a wide spectrum of immunomodulatory…

Following the recent regulatory approvals of a number of checkpoint inhibitor therapeutics, development of a wide array of immunomodulatory therapeutic…

Cell-based assays play an important role in determination of mechanism of action (MOA) for therapeutic antibodies, particularly when evaluating their…

Cystic fibrosis (CF) patients have mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel that result in reduced…

DiscoveRx previously introduced a protein-protein interaction system using enzyme fragment complementation that provides a robust, HTS friendly format for monitoring…

Orphan GPCRs continue to represent a target class with immense potential for the discovery of novel therapeutic compounds. In spite…

Kinase targets have been extensively studied in biochemical assays using purified protein fragments for the kinase and the substrate. However,…