| Biological Information | |
|---|---|
| Background Information: | A-1210477 is a small molecule MCL-1 inhibitor with sufficient potency to disrupt the tight-binding MCL-1-BIM complex in living cells, achieving the hallmarks of intrinsic apoptosis, and demonstrating clear-on-target cancer cell killing capability either as a single agent or in combination with ABT-263 (Navitoclax). Provided as 5 mg of dry powder. |
| Target Name: | A-1210477 |
| Usage | |
| Product Type: | Control Ligands & Inhibitors |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Store at -20°C. Please avoid multiple freeze/thaw cycles. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Additional Information | |
| Brand: | DiscoverX |
A-1210477
A-1210477 is an binding inhibitor for MCL-1’s ability to bind to BIM. This product is provided as 5 mg of dry powder.
Datasheets
92-1309 Datasheet
View Document