| Biological Information | |
|---|---|
| Background Information: | Mammalian casein kinase 1 (CK1) gene family consists of seven different genes in mammals, CKIa, b, g1, g2, g3, d and e. These enzymes are important component of signal transduction pathways, regulates cell growth, division and differentiation, and the activities of a variety of oncoproteins and transcription factors. CSNK1G1 (Casein kinase I gamma1 isoform) plays an important role in cell survival and protects regulatory proteins from caspase-mediated degradation in apoptosis. Inhibitors may find clinical use for the treatment of Alzheimer's disease and amyotrophic lateral sclerosis.
GenBank NM_022048 |
| Target Class: | Kinase |
| Accession Number: | NM_022048.3 |
| Target Name: | CK1γ1 |
| Target Aliases: | CSNK1G1 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
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Casein Kinase 1gamma1, active
N-terminal 6His-tagged recombinant, human Casein Kinase 1γ1 amino acids 25-355.
Datasheets
14-711x Datasheet
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