| Biological Information | |
|---|---|
| Background Information: | The ChemiScreen™ GABAB Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of GABBR1 - GABBR2 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. |
| Target Class: | GPCR |
| Family: | GABAB Receptors |
| Accession Number: | NM_021903, NM_005458 |
| Target Name: | GABBR1-GABBR2 |
| Target Aliases: | GABBR1 - GABBR2, GABAB, GABAB |
| Target Species: | Human |
| Cell Background: | Chem-1 |
| Usage | |
| Product Type: | Membrane Preparations |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Assay Information | |
| Assay Measures: | Binding |
| Detection Method: | FluorescenceRadioactivity |
| Additional Information | |
| Brand: | ChemiSCREEN™ |
ChemiScreen™ GABAB Receptor Membrane Preparation
The ChemiScreen™ GABAB Receptor Membrane Preparation measures ligand binding to GABBR1 – GABBR2 GPCR via radioligand binding assays. Membrane preps contain 1mL of 1mg/mL frozen membranes.
Datasheets
HTS119M Datasheet
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