| Biological Information | |
|---|---|
| Background Information: | Embelin is a natural cell-permeable benzoquinone inhibitor of the X-linked inhibitor of apoptosis (XIAP) protein (IC50=4.1uM), acting as an anti-tumor, anti-inflammatory, and analgesic. Activates caspases, blocks growth, and promotes apoptosis in tumor cells with high levels of XIAP. Also prevents XIAP- and caspase-dependent inflammation, and inhibits IKK, preventing NF-kB activation. Also acts as an agonist for GPR84. Provided as 10 mg of dry powder. |
| Target Name: | Embelin |
| Usage | |
| Product Type: | Control Ligands & Inhibitors |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Store at 2-8°C. Please avoid multiple freeze/thaw cycles. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Additional Information | |
| Brand: | DiscoverX |
Embelin
Embelin is an agonist for GPR84 and an inhibitor for XIAP. This product is provided as 10 mg of dry powder.
Datasheets
92-1202 Datasheet
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