| Biological Information | |
|---|---|
| Background Information: | N-terminal 6His-tagged recombinant, human Met amino acids 974-end, containing the mutation Y1248D. Met Y1248D is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). in vitro studies have demonstrated that this mutation has a moderate transforming ability. |
| Target Class: | Kinase |
| Family: | Receptor Tyrosine Kinase (RTK): Type X RTK: HGF Receptor Family |
| Accession Number: | Refer to CoA for Accession Number |
| Target Name: | MET (c-MET) |
| Target Aliases: | Hepatocyte growth factor receptor, HGFR, tyrosine-protein kinase Met, MET, AUTS9, c-Met, RCCP2, HGFR |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
Met (Y1248D), active
10 µg of active Met. N-terminal 6His-tagged recombinant, human Met amino acids 974-end, containing the mutation Y1248D.
Datasheets
14-816x Datasheet
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