| Biological Information | |
|---|---|
| Background Information: | N-terminal GST-tagged recombinant, human full length p38α/SAPK2a containing the mutation T106M. Activated using DD-MKK6 (14-537) and repurified using glutathione-agarose. Contains the gatekeeper mutation T160M in the ATP-binding domain. This mutation increases resistance to SB203580 as compared to the wild type sequence. |
| Target Class: | Kinase |
| Family: | Ser/Thr Kinase; MAPK; p38 Family |
| Accession Number: | NM_001315.1; NM_139012.1; NM_139013.1; NM_139014.1 |
| Target Name: | p38α/SAPK2a |
| Target Aliases: | MAPK14, p38, CSBP, PRKM15, PRKM14, RK, SAPK2A, CSBP1, CSPB1, Mxi2, p38ALPHA, MXI2, EXIP, CSBP2 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -20°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
p38alpha/SAPK2a (T106M), active
10 µg of active p38α/SAPK2a. N-terminal GST-tagged recombinant, human full length p38α/SAPK2a containing the mutation T106M.
Datasheets
14-687x Datasheet
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