| Biological Information | |
|---|---|
| Background Information: | PD0325901 is a synthetic, orally active MEK1 and MEK2 inhibitor (Ki=1.1 and 0.79, respectively) that research shows inhibits the growth of melanoma cell lines in vitro and in vivo. Has antiangiogenic activity via inhibiting production of VEGF proangiogenic cytokines, and suppresses the phosphorylation of ERK and the RAS/RAF/MEK/ERK signaling pathway, which is frequently active in tumors. Provided as 5 mg of dry powder. |
| Target Name: | PD0325901 |
| Usage | |
| Product Type: | Control Ligands & Inhibitors |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Store at ≤-20°C. Please avoid multiple freeze/thaw cycles. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Additional Information | |
| Brand: | DiscoverX |
PD0325901
PD0325901 is an inhibitor of MEK1 and MEK2. This product is provided as 5 mg of dry powder.
Datasheets
92-1184 Datasheet
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