| Biological Information | |
|---|---|
| Background Information: | Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family.
GenBank NM_005028 |
| Target Class: | Kinase |
| Family: | Lipid Kinase |
| Accession Number: | NM_005028 |
| Target Name: | PIP4K2α |
| Target Aliases: | PIP4K2A, PIP5K2, PIP5K2A |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
PIP4K2alpha, active
N-terminal 6His-tagged recombinant, human PIP4K2α, full length.
Datasheets
14-901x Datasheet
View Document