| Biological Information | |
|---|---|
| Background Information: | KPCZ (Protein kinase C, zeta type, nPKC-zeta, EC 2.7.1.37) is one of the major protein kinase C (PKC) isoforms of a family of serine/threonine protein kinases. Breakdown of phosphatidylinositol leads to formation of diacylglycerol and inositol triphosphate, the former acting synergistically with Ca2+ to activate PKC, resulting in translocation of the enzyme from cytosol to the membrane. Phosphorylation of proteins by PKC has been implicated as a pivotal regulatory element in signal transduction, cellular regulation, and with a high affinity to phorbol ester tumor promoters.
GenBank BC014270 |
| Target Class: | Kinase |
| Accession Number: | NM_001033581.1; NM_001033582.1; NM_002744.4 |
| Target Name: | PKCζ |
| Target Aliases: | PRKCZ, OTTHUMP00000044160, nPKC-zeta, PKC2 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
PKC zeta, active
N-terminal 6His-tagged recombinant, human PKC zeta, amino acids 2-end.
Datasheets
14-525x Datasheet
View Document