| Biological Information | |
|---|---|
| Background Information: | PrecisION™ hERG (CHO-K1) Ready-to-Assay Frozen Cells provides an easy-to-use cell based assay to study hERG ion channels, including drug candidates which affect channel function. These Ready-To-Assay Frozen Cells enables assessment of ion channel function via detection of electrophysiological signals. The included cells overexpress hERG ion channels. Upon voltage-induced channel activation, response can be detected via automated or manual electrophysiological techniques. These cells are provided as single-use vials of cryopreserved cells. |
| Target Class: | Ion Channel |
| Family: | Potassium |
| Sub Family: | Voltage-Gated |
| Accession Number: | U04270 |
| Target Name: | hERG |
| Target Aliases: | Potassium voltage-gated channel, eag-related protein 1, subfamily H (eag-related), erg1, ERG-1, ether-a-go-go-related gene potassium channel 1, HERG, potassium channel |
| Target Species: | Human |
| Cell Background: | CHO-K1 |
| Usage | |
| Product Type: | Frozen Cells |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Store in vapor phase of liquid nitrogen. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Assay Information | |
| Assay Type: | Functional |
| Assay Measures: | Electrophysiology |
| Detection Method: | Electrophysiology |
| Clinical Relevance | |
| Therapeutic Area: | Cardiovascular |
| Additional Information | |
| Brand: | PrecisIONTM |
PrecisION™ hERG (CHO-K1) Ready-to-Assay Frozen Cells
PrecisION™ hERG (CHO-K1) Ready-to-Assay Frozen Cells is used to assess hERG ion channel activity via electrophysiological measurements. These cells ship as single-use vials of cryopreserved cells.
Datasheets
CYL3038RTA-DataSheet
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