Biological Information | |
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Background Information: | PrecisION™ hNav1.5 (HEK 293) Ready-to-Assay Frozen Cells provides an easy-to-use cell based assay to study Nav1.5 ion channels, including drug candidates which affect channel function. These Ready-To-Assay Frozen Cells enables assessment of ion channel function via detection of electrophysiological signals. The included cells overexpress Nav1.5 ion channels. Upon voltage-induced channel activation, response can be detected via automated or manual electrophysiological techniques. These cells are provided as single-use vials of cryopreserved cells. |
Target Class: | Ion Channel |
Family: | Sodium |
Sub Family: | Voltage-Gated |
Accession Number: | NM_000335 |
Target Name: | Nav1.5 |
Target Aliases: | cardiac sodium channel, Skm2, SkMII, sodium channel protein type 5, sodium channel, voltage-gated, type V, alpha subunit, sodium channel, voltage gated, type V alpha subunit, sodium channel |
Target Species: | Human |
Cell Background: | HEK293 |
Usage | |
Product Type: | Frozen Cells |
Application: | Drug Discovery & Development |
Storage Conditions: | Store in vapor phase of liquid nitrogen. |
Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
Assay Information | |
Assay Type: | Functional |
Assay Measures: | Electrophysiology |
Detection Method: | Electrophysiology |
Clinical Relevance | |
Therapeutic Area: | Cardiovascular |
Additional Information | |
Brand: | PrecisIONTM |
PrecisION™ hNav1.5 (HEK 293) Ready-to-Assay Frozen Cells
Datasheets
CYL3004RTA-DataSheet
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