| Biological Information | |
|---|---|
| Background Information: | N-terminal GST-tagged, recombinant, full length, human PRKG2. PRKG2 is a member of the serine/threonine protein kinase family. Crucial regulator of intestinal secretion and bone growth. Acts downstream of NMDAR to activate the plasma membrane accumulation of GRIA1/GLUR1 in synapse and increase synaptic plasticity. Acts as regulator of gene expression and activator of the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2 in mechanically stimulated osteoblasts. |
| Target Class: | Kinase |
| Family: | AGC (protein kinase A, G, & C) |
| Sub Family: | Serine/threonine kinase |
| Accession Number: | BC111597.2 |
| Target Name: | PRKG2 |
| Target Aliases: | PRKGR2, PKG2, cGKII, PRKG2, cGK 2, cGK2, cGMP-dependent protein kinase 2 cGMP-dependent protein kinase II, Q13237 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 12 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Assay Information | |
| Assay Type: | Biochemical |
| Clinical Relevance | |
| Therapeutic Area: | Oncology/Immuno-Oncology |
PRKG2, active
10 µg of active PRKG2. N-terminal GST-tagged, recombinant, full length, human PRKG2.
Datasheets
15-006_Datasheet
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