| Biological Information | |
|---|---|
| Background Information: | 4-1BB-L, also called CD137L or TNFSF9, is a transmembrane glycoprotein belonging to the TNF superfamily and is involved in reverse signaling that induces apoptosis in T cells and cytokine secretion by monocytes. 4-1BB-L, the ligand for the co-stimulatory immune checkpoint receptor CD137/TNFRSF9/4-1BB, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. 4-1BB-L signaling through agonism at the 4-1BB receptor induces CD4+ and CD8+ T cells to proliferate and secrete cytokines. Provided as 25 μg of dry powder alongside reconstitution buffer. |
| Target Name: | 4-1BB-L |
| Usage | |
| Product Type: | Recombinant Proteins |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Store at -20°C. Please avoid multiple freeze/thaw cycles. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Additional Information | |
| Brand: | DiscoverX |
Recombinant Human 4-1BB-L
Recombinant Human 4-1BB-L is an agonist for TNFRSF9 (CD137). This product is provided as 25 μg of dry powder alongside reconstitution buffer.
Datasheets
92-1321 Datasheet
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