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PathHunter® Aflibercept Bioassay HS Kit

PathHunter Aflibercept Bioassay HS Kit delivers a robust, highly sensitive, and easy-to-use functional cell-based assay to determine Aflibercept drug potency and detect neutralizing antibodies. This bioassay HS kit has been optimized further to deliver reproducible results with lower variability. The bioassay kit contains all the materials needed for a complete assay, including cryopreserved cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The ready-to-use cryopreserved cells have been manufactured to ensure assay reproducibility and faster implementation from characterization to lot release. This bioassay has been optimized and qualified with the marketed biologic drug, Eylea® which is not provided in the bioassay kit.

Catalog No. Size Price Quantity
93-0996Y1-00154 1000 dp (10 x 96-well) $9,980.00
93-0996Y1-00153 200 dp (2 x 96-well) $2,979.00
Please contact Customer Service at customerservicedrx@eurofins.com for European (EUR) or United Kingdom (GBP) pricing or log in to see your account-specific pricing.

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Target/Description
Kinase Insert Domain Receptor
Group
Receptor Tyrosine Kinase
Cell Background
HEK 293
Receptor Species
Human
Accession Number
NM_002253.2
Agonist/Ligand
VEGF-165
Assay Measures
Dimerization
Bioassay Target Name
KDR/KDR
Assay Qualified With
Eylea®
Drug Trademark Owner
Eylea® is a registered trademark of Regeneron Pharmaceuticals, Inc.
Format
See User Manual for Product Configuration Details. The purpose of the control ligand included in the Bioassay Kit is for verification of assay performance relative to the data shown in the Certificate of Analysis for that kit. This control ligand is not intended for use as a reference standard for validation studies and lot release applications. Typically, a reference medicinal product (RMP) that has been pre-defined by the customer as an internal reference standard is used for those applications. The RMP is not provided with the bioassay kit or supplied by Eurofins DiscoverX.
Storage
Short term (<24 h): Store at -80°C; Long term (>24 h): Store in vapor phase of liquid nitrogen.
Coupling
N/A

  • [User Manual] PathHunter® Aflibercept Bioassay HS Kit

    PathHunter Aflibercept Bioassay HS Kit provide a functional, robust, highly sensitive, and easy-to-use cell-based assay to study aflibercept potency and neutralizing antibodies. The bioassay kits contain all the reagents needed for a complete assay including cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The pre-validated, frozen cells have been man...

    [User Manual] PathHunter® Aflibercept Bioassay HS Kit