PathHunter® eXpress CXCR2 CHO-K1 β-Arrestin GPCR Assay

PathHunter eXpress β-Arrestin kits are complete, assay-ready kits that provide a robust and easy-to-use, cell-based functional assay to study GPCR activity through β-arrestin recruitment. The pre-validated, frozen eXpress cells have been manufactured for single-use and are provided in a convenient, ready-to-screen format that eliminates the need for lengthy, expensive and time-consuming cell culture, making functional testing fast and convenient.

Catalog No. Size Price Quantity
93-0202E2CP2M 200 dp (2 x 96-well) $2,279.00
93-0202E2CP2L 1000 dp (10 x 96-well) $7,479.00

Please contact Customer Service at customerservicedrx@eurofins.com for European (EUR) or United Kingdom (GBP) pricing or log in to see your account-specific pricing.

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Target/Description
Chemokine (C-X-C motif) receptor 2
Group
Chemokine
Cell Background
CHO-K1
Receptor Species
Human
Accession Number
NM_001557
Agonist/Ligand
Recombinant Human IL-8 (CXCL8)
Assay Measures
β-Arrestin
Bioassay Target Name
CXCR2
Cells were plated in a 96-well plate and stimulated with a control agonist. Following stimulation, signal was detected according to the recommended protocol.
Format
See User Manual for Product Configuration Details
Storage
Short term (<24 h): Store at -80°C; Long term (>24 h): Store in vapor phase of liquid nitrogen.
β-Arrestin Isoform
β-Arrestin-2
Coupling
Gi/Go
  • [User Manual] PathHunter® β-Arrestin eXpress GPCR Assay

    PathHunter β-Arrestin cell lines are stable clonal cell lines that expedite drug discovery and development by providing robust response to over 90% of all known G-protein coupled receptor (GPCRs), with accurate pharmacology. This assay measures an essential pathway in GPCR activation, i.e., β-arrestin recruitment to activated GPCRs, enabling scientist...

    [User Manual] PathHunter® β-Arrestin eXpress GPCR Assay