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4-CMTB

4-CMTB or 4-chloro-α-(1-methylethyl)-N-2-thiazolylbenzeneacetamide, is a free fatty acid receptor FFA2 agonist and positive allosteric modulator. Binds at a site distinct from the orthosteric site; modulates the activity of short-chain fatty acids at FFA2 via the FFA2 second extracellular loop (ECL2).

Catalog No. Size Price Quantity
92-1300 10 mg $304.00

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Description
4-CMTB
Compound Type
Agonist
Storage
2-8°C
Source
Synthetic
Cells were plated in a 384-well plate and incubated overnight at 37°C/5% CO2 to allow the cells to attach and grow. Cells were then stimulated with a control agonist, using the assay conditions described below. Following stimulation, signal was detected using the PathHunter Detection Kit according to the recommended protocol.