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5-OXOETE

5-OxoETE is a keto acid analog of 5-hydroxyicosatetraenoic acid (5-HETE) that stimulates cytosolic calcium mobilization in neutrophils, actin polymerization, CD11b expression, and L-selectin shedding. It is a chemoattractant for eosinophils, neutrophils, basophils and monocytes, and an agonist of oxoeicosanoid (OXE) receptors (EC50=0.33nM).

Catalog No. Size Price Quantity
92-1042 25 µg $145.00

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Description
5-OXOETE
Compound Type
Agonist
Storage
≤ -20°C
Source
N/A
Cells were plated in a 384-well plate and incubated overnight at 37°C/5% CO2 to allow the cells to attach and grow. Cells were then stimulated with a control agonist, using the assay conditions described below. Following stimulation, signal was detected using the PathHunter Detection Kit according to the recommended protocol.