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Anti-CTLA4 Antibody [14D3]

CTLA4, or CTLA-4 is also known as cytotoxic T-lymphocyte-associated protein 4 or CD152. This monoclonal antibody binds human CTLA4, which functions as a immune checkpoint receptor that downregulates the immune system. CTLA4 is expressed on activated T cells and binds the B7 family members, CD80 (B7-1) and CD86 (B7-2), and the protein restricts the progression of T cells to an activated state by inhibiting IL-2 secretion and cellular proliferation.

Catalog No. Size Price Quantity
92-1319 100 µg $485.00

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Description
Anti-CTLA4 Antibody [14D3]
Compound Type
Antagonist
Storage
2-8°C
Source
Mouse Monoclonal to Human CTLA4
Signaling assay cells were seeded in a 96-well plate and then pre-incubated with a control antibody, followed by co-incubation with the ligand cell line using the assay conditions described below. Following stimulation, signal was detected using the PathHunter Detection Kit according to the recommended protocol.