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PFI-3

PFI-3 is a synthetic inhibitor of the SMARCA4 and PB1(5) bromodomains (KD=89 and 48nM, respectively). Also inhibits SMARCA2, and is otherwise selective over other bromodomain families. May play a role in SMARCA4 related cancers.

Catalog No. Size Price Quantity
92-1260 1 mg $85.00

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Description
PFI-3
Compound Type
Agonist
Storage
-20°C
Source
synthetic
Cells were plated in a 384-well plate and incubated overnight at 37°C/5% CO2 to allow the cells to attach and grow. Cells were then stimulated with a control compound, using the assay conditions described below. Following treatment, signal was detected using the InCELL Hunter Detection Kit according to the recommended protocol.