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Recombinant Human IL-23

Interleukin 23 (IL-23) is a cytokine protein and intricate member of the immune response. Composed of IL-23A and the p40 subunit of IL-12 (IL-12B). Agonist of the receptor formed by IL-12RB1 and IL-23R. Responsible for activation of STAT4 and production of IFNG, acting preferentially on CDR(+) T cells. Activates the JAK-STAT pathway, promoting production of pro-inflammatory cytokines. May be implicated in autoimmune inflammatory diseases and tumorigenesis.

Catalog No. Size Price Quantity
92-1266 10 µg $371.00

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Description
Recombinant Human IL-23
Compound Type
Agonist
Storage
-20°C
Source
Recombinant
Cells were seeded in a 96-well plate, incubated at 37°C / 5% CO2 followed by stimulation with a control ligand, as defined in the assay conditions below. After stimulation, assay signal was detected using the PathHunter® detection kit according to the recommended protocol.