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Recombinant Human PDGF-BB

Platelet-derived growth factor BB (PDGF-BB) is a homodimeric protein that is released upon platelet activation that induces proliferation, migration, and survival of endothelial, epithelial, and smooth muscle cells, as well as fibroblasts. Potent mitogen for mesenchymal cells. Able to bind all three of the PDGF receptors, and plays an important part in healing, regeneration, and angiogenesis and formation of smooth muscle during embryonic development. May facilitate tumor metastasis and vascularization.

Catalog No. Size Price Quantity
92-1110 2 µg $98.00

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Description
Recombinant Human PDGF-BB
Compound Type
Agonist
Storage
≤ -20°C
Source
E. coli
Cells were plated in a 384-well plate and incubated at 37°C/5% CO2 to allow the cells to attach and grow. Cells were then stimulated with a control agonist, using the assay conditions described below. Following stimulation, signal was detected using the PathHunter Detection Kit according to the recommended protocol.