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SANT-1

SANT-1 or N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine, is a potent (high affinity) antagonist of smoothened activity and cell-permeable inhibitor of Sonic hedgehog (Shh) signaling.

Catalog No. Size Price Quantity
92-1306 10 mg $316.00

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Description
SANT-1
Compound Type
Agonist
Storage
2-8°C
Source
Synthetic
Cells were plated in a 384-well plate and incubated for at least 4 hours at 37°C/5% CO2 to allow the cells to attach. Cells were then stimulated with a control compound, using the assay conditions described below. Following stimulation, signal was detected using the PathHunter Detection Kit according to the recommended protocol.