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Zaprinast

Zaprinast is a synthetic cGMP-specific phosphodiesterase (PDE) inhibitor from which sildenafil (Viagra) was developed. It is selective for PDE5, PDE6, PDE9 and PDE11 (IC50s of 0.76, 0.15, 29, and 12 uM, respectively), and is also a GPR35 agonist. It was an unsuccessful clinical drug candidate.

Catalog No. Size Price Quantity
92-1048 10 mg $79.00

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Description
Zaprinast
Compound Type
Agonist
Storage
2-8◦C
Source
Synthetic
Cells were plated in a 96-well plate and stimulated with a control agonist, using the assay conditions described below. Following stimulation, signal was detected according to the recommended protocol.