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Panel Screening & Profiling Services

DiscoveRx offers multiple pre-selected panels run at regularly scheduled intervals

Human Primary Cell Phenotypic Profiling Services

The BioMAP® Platform consists of primary human cell-based assay systems, a database of reference compound profiles, and computational data mining and analysis tools. In each BioMAP System, various primary human cell types are stimulated such that multiple, disease relevant signaling pathways are active, capturing pathway and interactions that manifest in the diseased tissue.

GPCRs

Multiple services for interrogating compound activity against the largest collection of naturally coupled GPCR cell lines. Over 400 assays available for measuring arrestin recruitment, second messenger signaling and receptor internalization.
Panels gpcrMAX, orphanMAX & Therapeutic gpcrPANELS

Nuclear Hormone Receptors (NHRs)

Two assay formats available for NHR signaling: Nuclear Translocation and Steroid Co-factor interaction. These cell based assays cover the majority of Nuclear Hormone receptors and provide powerful alternatives to gene reporter approaches.
Panels nhrMAX

Kinases

Industry leading portfolio of biochemical and cell-based kinase assays allowing researchers an unparalleled understanding of compound selectivity and affinity.

Cell-Based Kinases

Expanding menu of functional cell-based assays that measure inhibition of Receptor Tyrosine Kinase (RTK) and Cytosolic Tyrosine Kinase (CTK) signaling in a physiologically relevant context.
Panels tkMAX

KINOMEscan®

Active site-directed competition binding assays for more than 450 kinases and disease relevant mutant variants.
Panels scanMAX, scanEDGE, scanLIPID, scanTK & more

Epigenetic Targets

Active site-directed competition binding assays for more than 450 kinases and disease relevant mutant variants.
Panels bromoMAX, bromoELECT, bromoKdELECT  & more

 

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