DiscoverX is now a part of Eurofins Pharma Discovery Services
Contact
my cart
log-in
Search for:
Search for:
services
Drug Discovery Services
BioMAP® Primary Human Cell Profiling
KINOME
scan
® Kinase Screening & Profiling
PathHunter® Cell-Based Profiling
GPCR Screening & Profiling
SAFETYscan™ Profiling
BROMO
scan
® Bromodomain Screening & Profiling
BCL2
scan
™ Screening & Profiling
Contract Screening & Profiling
Library Profiling
Panel Screening & Profiling
Pathway Profiling (PATH
scan
™)
Nuclear Receptor Profiling (NHR
scan
™)
Quick Links
Request a Quote
Explore our Panels
TREE
spot
Login
Panel Test Dates
Special Offers
Custom Assay Development Services
Custom Assay Development
Cell Line Engineering & Development
Custom Formulation & Bulk Services
Bulk Cell Scale Up
Kit Packaging & Formulation
applications / products
Application Areas
Bioassays for Biosimilars
Biologics & Bioassays
Combination Therapies
Dimerization Assays
GPCR Solutions
Immuno-Oncology
KILR Cytotoxicity Assays
Kinase Solutions
Target Engagement Assays
Therapeutic/Disease Area
Toxicity & Safety
Special Offers
Product Types
Cell Lines
Assay Ready Kits
Detection Reagents
Biochemical Assays
Cell Culture Reagents
Ligands & Inhibitors
Build Your Own Assay Tools
View all products
Assay Development Services
Screening & Profiling
targets
View:
Alphabetical Target List
GPCRs
Browse by:
alphabetical target list
family
Arrestin
Cyclic AMP
Receptor Internalization
Pharmacochaperone Assays
kinases
Browse by:
alphabetical target list
group
Cell Based Assays
Biochemical Assays
ADP Assays
epigenetics
Browse by:
alphabetical target list
Bromodomain
Methyltransferase
Biochemical Assays
Cell Based Assays
Assay Development Services
Checkpoint Assays
Browse by:
alphabetical target list
assay development services
Pathway Assays
Browse by:
alphabetical target list
screening & profiling
assay development services
nuclear receptors
Browse by:
alphabetical target list
Screening & Profiling
assay development services
technologies / platforms
Human Primary Cell Screening
BioMAP Primary Cell Screening Platform
Enzyme Fragment Complementation
Cell-Based EFC Assay Platform
InCELL Target Engagement
Arrestin
Internalization
Translocation
Biochemical EFC Assay Platform
Competition Binding Platform
KINOME
scan
BROMO
scan
Fluorescence Intensity
tools / resources
Contact Support
Webinars
Blog
Document Resource Library
Flyers & Product Brochures
User Manuals & Protocols
White Papers & Application Notes
Scientific Posters
Presentations
View All
LeadHunter Study Reports & Data Analysis
Calculators
Publications & References
KINOME
scan
®
Tools & Resources
contact
Customer Service & Technical Support
Ordering
Distributors
Locations
DiscoverX Corporate
DiscoverX Europe
DiscoverX S. San Francisco
DiscoverX San Diego
about us
Press Releases
Collaborations & Partnerships
Events & Conferences
Employment
Tools & Resources
/
Document Resource Library
Document Resource Library
Our online document resource library contains our most popular resources, tools and product literature, and are available for immediate download. To request printed copies, please select desired materials below and enter your address details at the bottom of the page.
Search within Document Resource Library
Search :
Targets :
Cytokine Receptor
Kinase
GPCR
Epigenetic
Ion Channel
Signaling Pathway
Nuclear Receptor
Protease
Brands :
PathHunter®
HitHunter®
KINOMEscan®
BROMOscan®
InCELL™
BioMAP
Language :
English
Japanese
Brochures
White Papers & App Notes
Scientific Posters
Presentations
User Manuals
Service Documents
Drug Candidate Assessment Resource Guide
Download as PDF
BioMAP® Diversity PLUS®
Download as PDF
GPCR Product Solutions
Download as PDF
Safety Profiling Services Brochure
Download as PDF
KILR CD16 Effector Cells
Download as PDF
Accelerating GPCR Drug Discovery and Development
Download as PDF
PathHunter iONCscan Services
Download as PDF
Custom Assay Development
Download as PDF
Eurofins DiscoverX Targets List
Download as PDF
HitHunter® cAMP Assays
Download as PDF
SAFETYscan™ In Vitro Pharmacological Profiling Services
Download as PDF
PathHunter® Protein Translocation Assays
Download as PDF
PathHunter® MAX Panel Screening & Profiling Services
Download as PDF
InCELL Target Engagement Assays
Download as PDF
PathHunter® Screening and Profiling Services for Drug Discovery
Download as PDF
In Vitro Pharmacology Services
Download as PDF
Accelerating Biosimilar & Biobetter Drug Development
Download as PDF
BioMAP® Phenotypic Profiling Services
Download as PDF
KINOMEscan® KdELECT® Kinase Screening and Profiling Services
Download as PDF
PathHunter® Build Your Own β-Arrestin Assays
Download as PDF
Enabling Cancer Immunotherapy
Download as PDF
PathHunter® Interleukin Assays
Download as PDF
KILR® Cytotoxicity Assays
Download as PDF
PathHunter® Checkpoint Signaling Assays
Download as PDF
KINOMEscan® Kinase Screening and Profiling Services
Download as PDF
GPCR Reference Guide
Download as PDF
BioMAP® Fibrosis Panel
Download as PDF
Enzyme Fragment Complementation Platform
Download as PDF
BioMAP® Combo ELECT Service
Download as PDF
BioMAP® T Cell Autoimmune Panel
Download as PDF
BioMAP® Oncology Panels
Download as PDF
GPCR PathHunter® Arrestin Publications
Download as PDF
SAFETYscan Case Study
Download as PDF
CAR-T Cell Screening in Tumor Spheroids using Corning® Spheroid Microplates and the KILR® Cytotoxicity Assay
Download as PDF
InCELL Pulse™ Target Engagement Kinase Reference Set
Download as PDF
An Easy-to-Use Assay to Measure Target Cell Death by Antibody Dependent Cellular Phagocytosis (ADCP)
Download as PDF
[White Paper] Accelerating Biosimilar & Biobetter Drug Development: Ready-to-Use, Cell-Based Assays for Potency and Lot Release Testing
Download as PDF
[App Note] PathHunter® GPCR Internalization Assays for Monitoring Receptor Endocytosis and Recycling
Download as PDF
[App Note] Discovery of Novel G-Protein or Arrestin-Biased Ligands Using a Suite of GPCR Signaling Platforms
Download as PDF
Automating a Direct, Cell-Based, Target-Compound Interaction Assay for G9a Histone Methyltransferase and Bromodomain Proteins
Download as PDF
BioSeek: Secondary Activity of an Adrenergic Receptor Antagonist Bridging the Gap from In Vitro to In Vivo
Download as PDF
BioSeek: Explaining a Clinical Adverse Event - Bridging the Gap from In Vitro to In Vivo
Download as PDF
BioSeek: Economic Impact of BioMAP® Profiling - Bridging the Gap from In Vitro to In Vivo
Download as PDF
BioSeek: Differentiating p38MAPK Inhibitors - Bridging the Gap from In Vitro to In Vivo
Download as PDF
Comprehensive analysis of kinase inhibitor selectivity
Download as PDF
Rapid Quantification of Bioactive Ligands in Serum and Human Plasma Using PathHunter® eXpress β-Arrestin GPCR Assays
Download as PDF
Evaluation of a New Intracellular Calcium Fluorescent Reagent Using the FDSS6000
Download as PDF
Enabling Functional Therapeutic Antibody Research Using PathHunter® β-Arrestin Technology
Download as PDF
Discovery of Novel G-Protein or Arrestin-Biased Ligands Using a Suite of GPCR Signaling Platforms
Download as PDF
Chemiluminescent cAMP Detection Using DiscoverX HitHunter® Kits Compared With TR-FRET Assays
Download as PDF
Propelling GPCR drug discovery with innovative products and services
Download as PDF
New Momentum for Kinase Drug Discovery
Download as PDF
Faster Chemiluminescent cAMP Detection by HitHunter® cAMP XS+ on the SpectraMax L Luminescence Microplate Reader
Download as PDF
[DOT 2018] Multiple Pathway Activation in a Human M4 Muscarinic Receptor Cell-Based Assay
Download as PDF
[DOT 2018] Combining the Power of Different Profiling Approaches to Better Understand the Activity of Kinase Inhibitor Drugs
Download as PDF
[DOT 2018] Binding and Functional Analysis -Complementary Approaches in Safety Pharmacology
Download as PDF
[DOT 2018] Interrogating Allosteric Interactions Using Multiple Readouts for GPCRs
Download as PDF
[Immuno-Oncology Summit 2018] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[Immuno-Oncology Summit 2018] Driving Robust and Reproducible ADCC and T Cell Redirection with Single Donor KILR® CD16 Effector Cells
Download as PDF
[Immuno-Oncology Summit 2018] Immune Checkpoint Inhibitor Profiling and Biomarker Identification Using Human Primary Cell BioMAP®Oncology Systems
Download as PDF
The Human GPCRome Wall Poster
Download as PDF
[PEGS 2018] Building Robust and Simple Cell-Based Assays for Interleukins and Their Receptors
Download as PDF
[PEGS 2018] Driving Robust and Reproducible ADCC and T Cell Redirection with Single Donor KILR® CD16 Effector Cells
Download as PDF
[PEGS 2018] Ready-to-Use Potency Assays for Bevacizumab, Aflibercept, & Ranibizumab
Download as PDF
[PEGS 2018] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[DDC 2018] Modifying Standard Assay for Assessing Allosteric Activity
Download as PDF
[DDC 2018] Binding and Functional Analysis - Complementary Approaches in Safety Pharmacology
Download as PDF
[US BEBPA 2018] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[Biologics 2018] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[Biologics 2018] Ready-to-Use Potency Assays for Bevacizumab, Aflibercept, & Ranibizumab
Download as PDF
[WCBP 2018] Ready-to-Use Potency Assays for Bevacizumab, Aflibercept, & Ranibizumab
Download as PDF
[WCBP 2018] Driving Robust and Reproducible ADCC and T Cell Redirection with Single Donor KILR® CD16 Effector Cells
Download as PDF
[WCBP 2018] Building Robust and Simple Cell-Based Assays for Interleukins and Their Receptors
Download as PDF
[WCBP 2018] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[IBS 2017] Qualified, Fit-for-Purpose Bioassays for Liraglutide and Exenatide as Frozen Ready-to-Use Cells
Download as PDF
[IBS 2017] Driving Robust and Reproducible ADCC and T Cell Redirection with Single Donor KILR® CD16 Effector Cells
Download as PDF
[WCB 2017] Development and Evaluation of a Novel Bioassay for Denosumab Activity
Download as PDF
[BEBPA 2017] Qualified, Fit-for-Purpose Bioassays for Liraglutide and Exenatide as Frozen Ready-to-Use Cells
Download as PDF
[BEBPA 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[BEBPA 2017] Driving Robust and Reproducible ADCC and T Cell Redirection with Single Donor KILR® CD16 Effector Cells
Download as PDF
[SPS 2017] Phenotypic Profiling in BioMAP® Human Primary Cell Systems Identifies a Tox Alert Signature for Skin Irritation
Download as PDF
[ELRIG 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[DOT 2017] Differentiated Receptor Pharmacology of Imipridone ONC201: The First DRD2 Antagonist in Clinical Development for Oncology
Download as PDF
[DOT 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[EULAR 2017] Systems-Based Investigation of the Anti-Immunogenic Potential of DMARDs for Rheumatoid Arthritis Using Human Primary Cell-Based BioMAP® Phenotypic Profiling
Download as PDF
[WPC 2017] Phenotypic Profiling in Human Primary Cell-Based Cell Systems Elucidates Mechanisms of Skin Irritation
Download as PDF
[WPC 2017] Single Donor KILR® CD16 Effector Cells to Drive Robust and Reproducible ADCC and T Cell Redirection
Download as PDF
[PEGS 2017] Single Donor KILR® CD16 Effector Cells to Drive Robust and Reproducible ADCC and T Cell Redirection
Download as PDF
[PEGS 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[PEGS 2017] Immune Checkpoint Inhibitor Profiling and Biomarker Identification Using Human Primary Cell BioMAP® Oncology Systems
Download as PDF
[ITOC 2017] Phenotypic Human Primary Cell-Based Tumor Microenvironment Models for Evaluation of Drug Combination for Immune Oncology
Download as PDF
[ICI 2017] Immune Checkpoint Inhibitor Profiling and Biomarker Identification Using Human Primary Cell BioMAP Oncology Systems
Download as PDF
[ICI 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[SOT 2017] Phenotypic Profiling in Human Primary Cell-Based Systems Provides Mechanistic Insight into the Cardiotoxicity of Tyrosine Kinase Inhibitors
Download as PDF
[Biologics Biosimilars Congress 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[Biologics Biosimilars Congress 2017] Specifically Measure Target Cell Death in a Co-Culture with ImmuneCells Through a Non-Radioactive, Dye-Free Cytotoxicity Assay
Download as PDF
[BEBPA USA 2017] Qualified, Fit-for-Purpose Bioassays for Liraglutide and Exenatide as Frozen Ready-to-Use Cells
Download as PDF
[BEBPA USA 2017] Ready-to-Use Potency Assays for Bevacizumab, Aflibercept, & Ranibizumab
Download as PDF
[BEBPA USA 2017] Development and Evaluation of a Novel Bioassay for Denosumab Activity
Download as PDF
[BEBPA USA 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[Advances in Drug Discovery 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[Advances in Drug Discovery 2017] A Duplexed Calcium and β-Arrestin Assay Protocol for Human Histamine H1 Receptor PathHunter CHO-K1 HRH1 β-Arrestin Cell Line
Download as PDF
[Biologics Biosimilars Congress 2017] Phenotypic Human Primary Cell-Based Tumor Microenvironment Models for Evaluation of Drug Combinations for Immune Oncology
Download as PDF
[SLAS 2017] CAR-T Cell Screening in Tumor Spheroids Using Corning Spheroid Microplates
Download as PDF
[SLAS 2017] Specifically Measure Target Cell Death in a Co-Culture with Immune Cells Through a Non-Radioactive, Dye-Free Cytotoxicity Assay
Download as PDF
[SLAS 2017] InCELL Pulse™: A Novel Cellular Target Engagement Assay Platform for Drug Discovery
Download as PDF
[SLAS 2017] Quantifying GPCR Signaling Bias: A Simple Approach to Quantify Selectivity and Agonist Bias
Download as PDF
[SLAS 2017] A Duplexed Calcium and β-Arrestin Assay Protocol for Human Histamine H1 Receptor PathHunter CHO-K1 HRH1 β-Arrestin Cell Line
Download as PDF
[DOT 2016] InCELL Pulse™: A Novel Cellular Target Engagement Assay Platform for Drug Discovery
Download as PDF
[2016 ELRIG Conference Poster] A Duplexed Calcium and β-Arrestin Assay Protocol for Human Histamine H1 Receptor PathHunter CHO-K1 HRH1 β-Arrestin Cell Line
Download as PDF
[2016 DOT Conference Poster] Interrogating Allosteric Interactions Using Multiple Readouts for GPCRs
Download as PDF
[2016 IRA Conference Poster] Building Better Cell-Based Assays for Interleukins and Their Receptors
Download as PDF
[2016 XXIV National Medicinal Chemistry] Interrogating Allosteric Interactions Using Multiple Readouts for GPCRs
Download as PDF
Phenotypic Profiling in BioMAP® Human Primary Cell Systems Identifies a Tox Alert Signature for Skin Irritation
Download as PDF
[2016 PEGS Conference] Novel, Improved Cell-based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[2016 PEGS Conference] Specifically Measure Target Cell Death in a Co-Culture with Immune Cells Through a Non-Radioactive, Dye-free Cytotoxicity
Download as PDF
Phenotypic Human Primary Cell-based Tumor Microenvironment Models for Evaluation of Drug Combinations for Immune Oncology
Download as PDF
Improved Cell-Based Assays To Assess Therapeutic Molecules Against Immune Checkpoint Receptors Such As PD-1, PD-L1 And PD-L2
Download as PDF
[2016 Biopharmaceutical Symposium] Rapidly Develop Simple Potency Assays for Interleukins & Their Receptors
Download as PDF
[2016 Biopharmaceutical Symposium] Ready-to-use potency assays for anti-VEGF drugs such as Bevacizumab
Download as PDF
[2016 SLAS Conference Poster] Phenotypic Characterization of CFTR Drugs, VX-770 and VX-809, in BioMAP® Human Primary Cell Systems Connects Target Biology to Disease Mechanisms
Download as PDF
[2016 SLAS Conference Poster] Improved Cell-Based Assays To Assess Therapeutic Molecules Against Immune Checkpoint Receptors Such As PD-1, PD-L1 and PD-L2
Download as PDF
[2015 BEBPA Conference Poster] Rapidly Develop Simple Potency Assays for Interleukins & Their Receptors
Download as PDF
[2015 BEBPA Conference Poster] Ready-to-use potency assays for anti-VEGF drugs like Bevacizumab
Download as PDF
Quantifying Signaling Bias: A Simple Approach to Quantify Functional Selectivity and Agonist Bias
Download as PDF
Novel Trafficking Assays For Pharmacochaperone Discovery Using Enzyme Fragment Complementation Applied To CFTR-ΔF508
Download as PDF
Utilisation of the InCELL Hunter™ Target Engagement Cell-Based Assay for Profiling of ULK1 Inhibitors
Download as PDF
Elucidating Mechanisms of Toxicity Using Human Primary Cell Systems
Download as PDF
[2015 WCI Conference] Predicting Drug-induced Skin Rash Using BioMAP Human Primary Cell-based Systems
Download as PDF
A novel dye-free cytotoxicity assay to selectively measure target cell death in ADCC, CDC CAR-T or T-cell activation assays
Download as PDF
[2015 WCI Conference] Measuring Receptor Dimerization To Create Functional Cell-Based Assays for ~85% of the Interleukin Receptor Family
Download as PDF
Simple, Reproducible & Robust Bioassays In Cryopreserved Ready-To-Assay Format
Download as PDF
Quantifying Signaling Bias: A Simple Approach to Quantify Functional Selectivity and Agonist Bias
Download as PDF
Advances in tools to compare potency, efficacy, safety & quality of follow-on biologics or biosimilars
Download as PDF
[2015 NAb Conference Poster] Robust and Simple Potency and NAb Bioassays for Avastin® Biosimilar Development
Download as PDF
[2015 SOT Conference Poster] Elucidating Mechanisms of Cardiovascular Toxicity Using Phenotypic Data from BioMAP Human Primary Cell Systems
Download as PDF
[2015 Bioassay Conference] Simple, Reproducible & Robust Bioassays in Cryopreserved Ready-To-Assay Format
Download as PDF
Analysis of α-PD-1, α-PD-L1 and α-CTLA-4 Immune Checkpoint Antibodies in Human Primary Cell BioMAP Oncology Systems
Download as PDF
Elucidating Mechanisms of Toxicity Using Phenotypic Data from Human Primary Cell Systems – a Chemical Biology Approach for Thrombosis-Related Side Effects
Download as PDF
[2015 SLAS Conference Poster] Novel Trafficking Assays for Pharmacochaperone Discovery Using Enzyme Fragment Complementation
Download as PDF
[2015 SLAS Conference Poster] BioMAP® Human Primary Cell Systems for Improving Drug Discovery and Development
Download as PDF
[2015 SLAS Conference Poster] Interrogating Allosteric interactions Using Multiple Readouts for GPCRs
Download as PDF
[2014 FAST Conference Poster] Effects of Bromodomain Inhibitors on Renal and Pulmonary Fibrosis
Download as PDF
[2014 ACR Conference Poster] Profiling 14-3-3η in Human Primary Cell Based Disease Models Reveals a Unique Pro-Inflammatory Phenotypic Signature Consistent with RA-Inflammation Biology
Download as PDF
[2014 ACR Conference Poster] Analysis of Anakinra in Primary Human Cell Systems Reveals an In Vitro Signature for Skin-related Side Effects
Download as PDF
Development of Simple, Robust Bioassays for Biosimilar & Biobetter Development
Download as PDF
GLP1 NAb Assay: A Case Study for Simple, Serum-tolerant Cell-based Assays to Detect Neutralizing Antibodies to Biosimilar and Bioinnovator drugs
Download as PDF
Novel Trafficking Assays for Pharmacochaperone Discovery Using Enzyme Fragment Complementation
Download as PDF
[AOM_RA-Infl_Paris] BioMAP® Systems Integrate Human Biology and Drug Discovery To Enable The Development of Safer and More Effective Anti-inflammatory Therapies
Download as PDF
[2014 World Pharma Congress] Phenotypic Screening of Compounds and Drug Combinations in BioMAP® Oncology Systems Reveals Divergent Effects on Clinically-relevant Biomarkers
Download as PDF
[2014 PEGS Conference] Development of Novel Cell-based Assays to Detect Neutralizing Antibodies to Therapeutic Biologics
Download as PDF
[2014 PEGS Conference] Validated Bioassays for Potency, Stability and Lot Release Testing of Biopharmaceuticals
Download as PDF
[2014 PEGS Conference] Detection of EGFR, HER2, HER3 and HER4 Hetero- and Homodimerization Using EFC-based Cellular Assays
Download as PDF
[2014 DDC Conference] Rational design of dual kinase-bromodomain inhibitors for therapeutic polypharmacology
Download as PDF
[2014 AACR Poster] Dual kinase/bromodomain inhibitors for rationally designed polypharmacology
Download as PDF
[2014 AACR Poster] Detection of EGFR, HER2, HER3 and HER4 Hetero- and Homodimerization Using EFC-based Cellular Assays
Download as PDF
Predictive Models for Mechanism-of-Action Classification of Chemicals Using Phenotypic Data
Download as PDF
In Vitro Bioactivity in ToxCast Assays for Fruit and Vegetable Extracts
Download as PDF
Predicting Toxic and Therapeutic Mechanisms of the ToxCast Chemical Library by Phenotypic Screening
Download as PDF
Understanding Mechanisms of Drug-Induced Liver Injury Using Primary Human Cell and Co-culture Systems
Download as PDF
The application of EFC technology to study forward trafficking of GPCRs
Download as PDF
[2013 Society of Toxicology Poster] - Phenotypic Approaches Defining Toxicity Mechanisms
Download as PDF
Primary Human Cell BioMAP® Profiling of Methotrexate, Tocilizumab, Adalimumab, and Tofacitinib
Download as PDF
Detection of Cytokine and Growth Factor Receptor Dimerization Using Enzyme Fragment Complementation
Download as PDF
Detection of Endogenous Ligand Bias: A Case Study Using the Chemokine Receptor Family
Download as PDF
BioMAP® Primary Human Cell Systems for Improving Drug Discovery and Development
Download as PDF
Validated Cell-Based Assays for Rapid Screening and Functional Characterization of Therapeutic Monoclonal Antibodies
Download as PDF
The Druggable GPCRome
The Human Bromodomain Family
Download as PDF
Validated Cell-Based Assays for Rapid Screening and Functional Characterization of Therapeutic Monoclonal Antibodies
Download as PDF
BROMOscan high throughput, quantitative ligand binding assays identify best in class bromodomain inhibitors from a screen of mature compounds thought to specifically target other protein classes
Download as PDF
A Novel Assay Platform for the Detection of Kinase-Inhibitor Binding in Intact Mammalian Cells
Download as PDF
Novel Assays and Human Model Systems for Epigenetic Drug Discovery
Download as PDF
Mix-and-Read Assays For Regulated Ubiquitination & Degradation of Proteins Using PathHunter® Technology
Download as PDF
InCELL Hunter™: A Novel Cellular Assay Platform for the Direct Measurement of Compound Binding to Intracellular Targets in Intact Mammalian Cells
Download as PDF
Multi-Parameter GPCR Screening: An Essential Tool for Uncovering GPCR Mutant Phenotypes
Download as PDF
Phenotypic Approaches Defining Toxicity Mechanisms
Download as PDF
BROMOscan high throughput, quantitative ligand binding assays identify best in class bromodomain inhibitors from a screen of mature compounds thought to specifically target other protein classes
Download as PDF
scanKINETIC: A broadly applicable tool for the kinetic characterization of interactions between small molecule inhibitors and protein targets from the kinase and bromodomain families
Download as PDF
A Novel Assay Platform for the Detection of Kinase-Inhibitor Binding in Intact Mammalian Cells
Download as PDF
The Human Kinome
Download as PDF
Utilization of PathHunter® Arrestin Cell Lines for Detection of Arrestin Biased Ligands and Compound Pharmacology Distinct from Second Messengers
Download as PDF
Unique Properties of PathHunter® β-Arrestin Assays for GPCR Antagonist Discovery and Characterization
Download as PDF
Ultrasensitive, 3456 or 1536-Well Miniaturization-Friendly Chemiluminescent Detection of PathHunter® Cell-Based GPCR and Kinase Assays
Download as PDF
PathHunter® β-Arrestin Assays: Determination of Pharmacology Differences Between Human and Ortholog GPCRs
Download as PDF
PathHunter® β-Arrestin Assays as a Universal Tool For Orphan GPCR Analysis
Download as PDF
PathHunter® Cell-Based Kinase Assays: A Portfolio of HTS-friendly Cytoplasmic or Receptor Tyrosine Kinase Assays for Small Molecule Inhibitors as well as Monoclonal Antibodies
Download as PDF
Novel Trafficking Assays for Pharmacochaperone Discovery Using Enzyme Fragment Complementation
Download as PDF
New Cell-Based Kinase Assays for TrkA and Other Receptor Tyrosine Kinases using PathHunter™ Protein-Protein Interaction Technology
Download as PDF
HitHunter® cAMP and cAMP Hunter™ Cell Line: Your Solution for Use with High Serum Samples, Difficult Gi Targets and Identification of Allosteric Modulators
Download as PDF
Functional Whole-cell Assays for Tyrosine Phosphorylation Using PathHunter® Technology
Download as PDF
Functional Receptor Tyrosine Kinase Assays for Antibody therapeutics Using PathHunter® Technology
Download as PDF
Dual Purpose Cell Lines for Analysis of GPCR/Arrestin Interaction using PathHunter® and Natural Gq-Coupling Using the Improved Calcium No-WashPLUS (CaNWPLUS) Kit
Download as PDF
Cell-Based Assays for G-Protein Independent Signaling Using Arrestin Binding and Endocytosis
Download as PDF
Application of the PathHunter® Protein Interaction Assay to Receptor Tyrosine Kinases (RTKs): Developing a Non-Antibody One-Step Cell-Based Kinase Activity
Download as PDF
ADP Hunter™ Plus: A Rapid, Quantitative HTS Assay for GDP and UDP
Download as PDF
A Wide Range of Compound Efficacies Revealed Using PathHunter® Arrestin Assays
Download as PDF
A High Sensitivity Assay for Kinetic Analysis of Kinases and ATPases Based on Measurement of ADP Accumulation
Download as PDF
[WCB 2018] Bioassays as Critical Reagents
Download as PDF
[DOT 2018] Development of High Throughput Cellular Thermal Shift Assays: Cellular Mechanistic Assays in Early Drug Discovery
Download as PDF
[Immuno-Oncology Summit 2018] Evaluating Immuno-Oncology (I-O) Potential of Compounds and Combinations Using In Vitro Human TME Models
Download as PDF
[PEGS 2018] Simplifying Implementation of Robust Bioassays in Development to QC Lot Release
Download as PDF
[DDC 2018] Binding and Functional Analysis - Complementary Approaches in Safety Pharmacology Using GPCRs
Download as PDF
[US-BEBPA 2018] Seamless Implementation of Robust and Simple Bioassays
Download as PDF
[US-BEBPA 2018] Generation of Cryopreserved (Ready-to-Use) Cells for Bioassays
Download as PDF
[Biologics 2018] Seamless Implementation of Robust and Simple Bioassays
Download as PDF
[SLAS 2018] Large Scale Profiling in Human Primary Cell-Based Phenotypic Assays Identifies Novel Outcome Pathways for Drug Efficacy in Cardiovascular Disease
Download as PDF
[WCBP 2018] Seamless Implementation of Robust and Simple Bioassays
Download as PDF
[WPC 2017] Human-Based Phenotypic Profiling Uncovers Mechanisms of Toxicity
Download as PDF
[Advances Immuno-Oncology 2017] Evaluating Immuno-Oncology Potential of Compounds and Combinations in BioMAP®
Download as PDF
[CASSS 2017] Robust and Reproducible ADCC and T Cell Redirection with CD16-Engineered Effector Cells
Download as PDF
[PEGS 2017] Enabling Technologies for Development and Optimization of Bi-Specific Antibodies for T Cell Redirection
Download as PDF
[ICI 2017] Evaluating Immuno-Oncology Potential of Compounds and Combinations in BioMAP
Download as PDF
[Biologics Biosimilars Congress 2017] Harnessing the Complexity of the Human Tumor Microenvironment to Guide Decisions in Discovery and Combinations
Download as PDF
[BEBPA USA 2017] Optimizing and Qualifying Bioassays for Biosimilars, Biobetters, and Innovator Drugs
Download as PDF
[Advances in Drug Discovery 2017] Enabling Cancer Immunotherapy: From Target to Phenotype
Download as PDF
[SLAS 2017] Combining Target-Based and Phenotypic Assays for Successful Drug Repurposing
Download as PDF
[2015 WCI Conference] Identification of Immunomodulatory and Anti-Fibrotic Actions of Nintedanib and Pirfenidone Using BioMAP® Human Primary Cell-based Disease Models
Download as PDF
Modelling the Host-‐Tumour Stromal and Vascular Microenvironments to Support Compound Screening and Therapeutic Development
Download as PDF
Extracting Meaning from Complex Data: Predictive Models for Mechanism of Action Classification from Phenotypic Assay Data – Application to Phenotypic Drug Discovery
Download as PDF
Primary Human Cell BioMAP® Profiling of Methotrexate, Tocilizumab, Adalimumab, and Tofacitinib Reveals Different Mechanisms of Action With Distinct Phenotypic Signatures
Download as PDF
The BioMAP® Platform of Primary Human Cell Systems for Phenotypic Drug Discovery and Development – Lessons Learned
Download as PDF
[DiscoverX/SGC Technology Symposium] - Epigenetic Target Identification for Musculoskeletal Disease
Download as PDF
[DiscoverX/SGC Technology Symposium] - Cracking the Histone Code? Development of small-molecule inhibitors of the bromodomain acetyl-lysine interaction
Download as PDF
[DiscoverX/SGC Technology Symposium] - Application of computational approaches to accelerate bromodomain drug discovery
Download as PDF
[DiscoverX/SGC Technology Symposium] - Integrated Solution for Epigenetic Drug Discovery and Development
Download as PDF
[DiscoverX/SGC Technology Symposium] - Targeting Bromodomains – BET and the wider target class
Download as PDF
[DiscoverX/SGC Technology Symposium] - Assays and Probes for Epigenetic Targets
Download as PDF
[DiscoverX/SGC Technology Symposium] - Selective Targeting of Protein Interactions Mediated by Epigenetic Effector Domains
Download as PDF
To B or Not To B: Phenotypic Profiling BTK Inhibitors in BioMAP® Systems
Download as PDF
Cell-based Receptor Tyrosine Kinase Screening Reloaded - Development of a new cellular assay system for a target protein so far resistent against HTS formats
Download as PDF
Using DiscoverX’s ADP QuestTM for Academic Screening of Novel Kinases
Download as PDF
[DiscoverX/SGC Technology Symposium] - Profiling Compounds in Primary Human Cell BioMAP Systems for Drug Discovery and Therapeutic Development in Inflammation and Cancer
Download as PDF
[User Manual] PathHunter® IL17RA/IL17RC Dimerization Bioassay Kit
Download as PDF
[User Manual] PathHunter® Checkpoint Assay - TNF Receptor Superfamily (TNFRSF)
Download as PDF
[User Manual] InCELL Hunter™ Target Engagement Cell Lines
Download as PDF
[User Manual] PathHunter® Sargramostim Bioassay Kit
Download as PDF
[User Manual] PathHunter® PD-1 Signaling Bioassay Kit
Download as PDF
[User Manual] PathHunter® Anakinra Bioassay Kit
Download as PDF
[User Manual] PathHunter® IL6R/IL6ST Bioassay Kit
Download as PDF
[User Manual] PathHunter® U2OS MC4R Bioassay Kit
Download as PDF
[User Manual] KILR® CD16 Effector Cells
Download as PDF
[User Manual] cAMP Hunter™ Follitropin Alfa Bioassay Kit
Download as PDF
[Technical Bulletin] Updated Cell Culture Protocol and Handling Procedure
Download as PDF
[User Manual] cAMP Hunter™ Exenatide Bioassay Kit
Download as PDF
[User Manual] cAMP Hunter™ Liraglutide Bioassay Kit
Download as PDF
[User Manual] PathHunter® IL-2 Bioassay Kit
Download as PDF
[User Manual] InCELL Hunter™ Target Engagement Assay Kit
Download as PDF
[User Manual] PathHunter® Pertuzumab Bioassay Kit
Download as PDF
[User Manual] PathHunter® CHO-K1 VIPR2 Bioassay Kit
Download as PDF
[User Manual] ProLabel® and ProLink™ Mammalian Cloning Vectors
Download as PDF
[User Manual] PathHunter® FGFR4-Beta-Klotho Bioassay Kit
Download as PDF
[User Manual] InCELL Pulse™ Target Engagement Starter Kit
Download as PDF
[User Manual] InCELL Pulse™ Cellular Target Engagement Assays
Download as PDF
[User Manual] InCELL Detection Kit
Download as PDF
[User Manual] PathHunter® Panitumumab Bioassay Kit
Download as PDF
[User Manual] PathHunter® Bioassay Detection Kit
Download as PDF
[User Manual] PathHunter® IGF1R Bioassay Kit
Download as PDF
[User Manual] PathHunter® TrkC Bioassay Kit
Download as PDF
[User Manual] PathHunter® EA Parental Cell Lines
Download as PDF
[User Manual] PathHunter® Co-Stimulatory Checkpoint Assay
Download as PDF
[User Manual] PathHunter® β-Arrestin2 Retroparticles
Download as PDF
[User Manual] PathHunter eXpress Degradation Assays
Download as PDF
[User Manual] KILR® Retroparticles For Cytotoxicity Assays
Download as PDF
[User Manual] PathHunter® IL1RL1/IL1RAP Dimerization Bioassay Kit
Download as PDF
[User Manual] PathHunter® PTH Bioassay Kit
Download as PDF
[User Manual] cAMP Hunter™ Teriparatide Bioassay Kit
Download as PDF
[User Manual] PathHunter® Checkpoint Signaling Assay - Immunoglobulin Superfamily (IgSF)
Download as PDF
[User Manual] PathHunter® Exendin-4 Bioassay Kit
Download as PDF
[User Manual] PathHunter® Bioassay ED Detection Kit
Download as PDF
[User Manual] cAMP Hunter™ Exendin-4 Bioassay Kit
Download as PDF
[User Manual] PathHunter® Insulin Bioassay Kit
Download as PDF
[User Manual] KILR® Detection Kit
Download as PDF
[User Manual] KILR® Cytotoxicity Assay−Adherent Target Cell Lines
Download as PDF
[User Manual] KILR® Assay for Suspension Cell Lines
Download as PDF
[User Manual] PathHunter® Ranibizumab Bioassay Kit
Download as PDF
[User Manual] PathHunter® Aflibercept Bioassay Kit
Download as PDF
[User Manual] PathHunter® GLP1 (7-37) Bioassay Kit
Download as PDF
[User Manual] PathHunter® Epoetin Alfa Bioassay Kit
Download as PDF
[User Manual] PathHunter® Insulin Lispro Bioassay Kit
Download as PDF
[User Manual] PathHunter® Insulin Glargine Bioassay Kit
Download as PDF
[User Manual] PathHunter® Bevacizumab Bioassay Kit
Download as PDF
[User Manual] PathHunter® Human Growth Hormone Bioassay Kit
Download as PDF
[User Manual] PathHunter® Darbepoetin Alfa Bioassay Kit
Download as PDF
[User Manual] PathHunter® Dimerization Bioassay Kit
Download as PDF
[User Manual] PathHunter® Receptor Tyrosine Kinase Bioassay Kit
Download as PDF
[User Manual] PathHunter® Cytokine Receptor Bioassay Kit
Download as PDF
[User Manual] cAMP Hunter™ GPCR Bioassay Kit
Download as PDF
[User Manual] PathHunter® GPCR Bioassay Kit
Download as PDF
[User Manual] HitHunter® cAMP Assay for Biologics
Download as PDF
[User Manual] HitHunter® cAMP Assay for Small Molecules
Download as PDF
[User Manual] InCELL Hunter™ eXpress Protein Binding Assays
Download as PDF
[User Manual] PathHunter® eXpress Cytosolic Tyrosine Kinase Activity Assay Kit
Download as PDF
[User Manual] PathHunter® eXpress Nuclear Translocation Assays
Download as PDF
[User Manual] PathHunter® Pharmacotrafficking Assays
Download as PDF
[User Manual] PathHunter® Dimerization Assay
Download as PDF
[User Manual] Native Calcium GPCR Assays
Download as PDF
[User Manual] PathHunter® eXpress Receptor Tyrosine Kinase Internalization Assay Kit
Download as PDF
[User Manual] PathHunter® eXpress Receptor Tyrosine Kinase Activity Assay Kit
Download as PDF
[User Manual] PathHunter® eXpress Dimerization Assay Kit
Download as PDF
[User Manual] PathHunter® NHR Assay
Download as PDF
[User Manual] InCELL Hunter™ eXpress Kinase Binding Assays
Download as PDF
[User Manual] InCELL Hunter™ eXpress Histone Methyltransferase Assays
Download as PDF
[User Manual] InCELL Hunter™ eXpress Bromodomain Assays
Download as PDF
[User Manual] PathHunter® Receptor Tyrosine Kinase Internalization Assays
Download as PDF
[User Manual] PathHunter® Receptor Tyrosine Kinase Activity Assay
Download as PDF
[User Manual] PathHunter® Cytosolic Tyrosine Kinase Functional Assay
Download as PDF
[User Manual] PathHunter® ProLabel®/ProLink™ Detection Kit
Download as PDF
[User Manual] PathHunter® Pathway Assay
Download as PDF
[User Manual] HitHunter® cGMP Assay
Download as PDF
[User Manual] Calcium No WashPLUS Assay Kit
Download as PDF
[User Manual] InCELL Hunter™ Bromodomain Cell-Based Assay
Download as PDF
[User Manual] ProLink™ Detection Kit
Download as PDF
[User Manual] PathHunter® ProLabel Detection Kit
Download as PDF
[User Manual] PathHunter® Flash Detection Kit
Download as PDF
[User Manual] PathHunter® EA Detection Kit
Download as PDF
[User Manual] PathHunter® β-Arrestin Assay for GPCR Cell Lines
Download as PDF
[User Manual] PathHunter® Total GPCR Internalization Assay
Download as PDF
[User Manual] PathHunter® Receptor Tyrosine Kinase Functional Assay
Download as PDF
[User Manual] PathHunter® GPCR Explorer Kit
Download as PDF
[User Manual] PathHunter® β-Arrestin eXpress GPCR Assay
Download as PDF
[User Manual] PathHunter® eXpress Total GPCR Internalization Assay
Download as PDF
[User Manual] PathHunter® eXpress Receptor Tyrosine Kinase Functional Assay Kit
Download as PDF
[User Manual] PathHunter® eXpress Nuclear Hormone Receptor Assay Kit
Download as PDF
[User Manual] PathHunter® eXpress Cytosolic Tyrosine Kinase Functional Assay Kit
Download as PDF
[User Manual] PathHunter® eXpress Activated GPCR Internalization Assay
Download as PDF
[User Manual] PathHunter® Detection Kit
Download as PDF
[User Manual] PathHunter® Activated GPCR Internalization Assay
Download as PDF
[User Manual] PathHunter® Cytosolic Tyrosine Kinase Activity Assay
Download as PDF
[User Manual] PathHunter® Bcl2–Bim Protein Interaction Assay
Download as PDF
[User Manual] EFC BlocDetect Kit
Download as PDF
[User Manual] cAMP Hunter™ Gs and Gi Cell Lines
Download as PDF
[User Manual] cAMP Hunter™ eXpress GPCR Assays
Download as PDF
BioMAP® T Cell Autoimmune Panel Sample Report
Download as PDF
BioMAP® Colorectal Cancer (CRC) Panel Sample Report
Download as PDF
BioMAP® Diversity PLUS Sample Report
Download as PDF
gpcrSCAN Sample Report
Download as PDF
scanMAX Sample Report
Download as PDF
gpcrMAX Sample Report
Download as PDF