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Document Resource Library
Document Resource Library
Our online document resource library contains our most popular resources, tools and product literature, and are available for immediate download. To request printed copies, please select desired materials below and enter your address details at the bottom of the page.
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Targets :
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Brochures
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Drug Candidate Assessment Resource Guide
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BioMAP® Diversity PLUS®
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GPCR Product Solutions
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Safety Profiling Services Brochure
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KILR CD16 Effector Cells
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Accelerating GPCR Drug Discovery and Development
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PathHunter iONCscan Services
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Custom Assay Development
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Eurofins DiscoverX Targets List
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HitHunter® cAMP Assays
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SAFETYscan™ In Vitro Pharmacological Profiling Services
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PathHunter® Protein Translocation Assays
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PathHunter® MAX Panel Screening & Profiling Services
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InCELL Target Engagement Assays
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PathHunter® Screening and Profiling Services for Drug Discovery
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In Vitro Pharmacology Services
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Accelerating Biosimilar & Biobetter Drug Development
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BioMAP® Phenotypic Profiling Services
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KINOMEscan® KdELECT® Kinase Screening and Profiling Services
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PathHunter® Build Your Own β-Arrestin Assays
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Enabling Cancer Immunotherapy
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PathHunter® Interleukin Assays
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KILR® Cytotoxicity Assays
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PathHunter® Checkpoint Signaling Assays
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KINOMEscan® Kinase Screening and Profiling Services
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GPCR Reference Guide
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BioMAP® Fibrosis Panel
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Enzyme Fragment Complementation Platform
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BioMAP® Combo ELECT Service
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BioMAP® T Cell Autoimmune Panel
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BioMAP® Oncology Panels
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GPCR PathHunter® Arrestin Publications
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SAFETYscan Case Study
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CAR-T Cell Screening in Tumor Spheroids using Corning® Spheroid Microplates and the KILR® Cytotoxicity Assay
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InCELL Pulse™ Target Engagement Kinase Reference Set
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An Easy-to-Use Assay to Measure Target Cell Death by Antibody Dependent Cellular Phagocytosis (ADCP)
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[White Paper] Accelerating Biosimilar & Biobetter Drug Development: Ready-to-Use, Cell-Based Assays for Potency and Lot Release Testing
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[App Note] PathHunter® GPCR Internalization Assays for Monitoring Receptor Endocytosis and Recycling
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[App Note] Discovery of Novel G-Protein or Arrestin-Biased Ligands Using a Suite of GPCR Signaling Platforms
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Automating a Direct, Cell-Based, Target-Compound Interaction Assay for G9a Histone Methyltransferase and Bromodomain Proteins
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BioSeek: Secondary Activity of an Adrenergic Receptor Antagonist Bridging the Gap from In Vitro to In Vivo
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BioSeek: Explaining a Clinical Adverse Event - Bridging the Gap from In Vitro to In Vivo
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BioSeek: Economic Impact of BioMAP® Profiling - Bridging the Gap from In Vitro to In Vivo
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BioSeek: Differentiating p38MAPK Inhibitors - Bridging the Gap from In Vitro to In Vivo
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Comprehensive analysis of kinase inhibitor selectivity
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Rapid Quantification of Bioactive Ligands in Serum and Human Plasma Using PathHunter® eXpress β-Arrestin GPCR Assays
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Evaluation of a New Intracellular Calcium Fluorescent Reagent Using the FDSS6000
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Enabling Functional Therapeutic Antibody Research Using PathHunter® β-Arrestin Technology
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Discovery of Novel G-Protein or Arrestin-Biased Ligands Using a Suite of GPCR Signaling Platforms
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Chemiluminescent cAMP Detection Using DiscoverX HitHunter® Kits Compared With TR-FRET Assays
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Propelling GPCR drug discovery with innovative products and services
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New Momentum for Kinase Drug Discovery
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Faster Chemiluminescent cAMP Detection by HitHunter® cAMP XS+ on the SpectraMax L Luminescence Microplate Reader
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[DOT 2018] Multiple Pathway Activation in a Human M4 Muscarinic Receptor Cell-Based Assay
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[DOT 2018] Combining the Power of Different Profiling Approaches to Better Understand the Activity of Kinase Inhibitor Drugs
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[DOT 2018] Binding and Functional Analysis -Complementary Approaches in Safety Pharmacology
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[DOT 2018] Interrogating Allosteric Interactions Using Multiple Readouts for GPCRs
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[Immuno-Oncology Summit 2018] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
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[Immuno-Oncology Summit 2018] Driving Robust and Reproducible ADCC and T Cell Redirection with Single Donor KILR® CD16 Effector Cells
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[Immuno-Oncology Summit 2018] Immune Checkpoint Inhibitor Profiling and Biomarker Identification Using Human Primary Cell BioMAP®Oncology Systems
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The Human GPCRome Wall Poster
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[PEGS 2018] Building Robust and Simple Cell-Based Assays for Interleukins and Their Receptors
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[PEGS 2018] Driving Robust and Reproducible ADCC and T Cell Redirection with Single Donor KILR® CD16 Effector Cells
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[PEGS 2018] Ready-to-Use Potency Assays for Bevacizumab, Aflibercept, & Ranibizumab
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[PEGS 2018] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
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[DDC 2018] Modifying Standard Assay for Assessing Allosteric Activity
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[DDC 2018] Binding and Functional Analysis - Complementary Approaches in Safety Pharmacology
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[US BEBPA 2018] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
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[Biologics 2018] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
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[Biologics 2018] Ready-to-Use Potency Assays for Bevacizumab, Aflibercept, & Ranibizumab
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[WCBP 2018] Ready-to-Use Potency Assays for Bevacizumab, Aflibercept, & Ranibizumab
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[WCBP 2018] Driving Robust and Reproducible ADCC and T Cell Redirection with Single Donor KILR® CD16 Effector Cells
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[WCBP 2018] Building Robust and Simple Cell-Based Assays for Interleukins and Their Receptors
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[WCBP 2018] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
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[IBS 2017] Qualified, Fit-for-Purpose Bioassays for Liraglutide and Exenatide as Frozen Ready-to-Use Cells
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[IBS 2017] Driving Robust and Reproducible ADCC and T Cell Redirection with Single Donor KILR® CD16 Effector Cells
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[WCB 2017] Development and Evaluation of a Novel Bioassay for Denosumab Activity
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[BEBPA 2017] Qualified, Fit-for-Purpose Bioassays for Liraglutide and Exenatide as Frozen Ready-to-Use Cells
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[BEBPA 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
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[BEBPA 2017] Driving Robust and Reproducible ADCC and T Cell Redirection with Single Donor KILR® CD16 Effector Cells
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[SPS 2017] Phenotypic Profiling in BioMAP® Human Primary Cell Systems Identifies a Tox Alert Signature for Skin Irritation
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[ELRIG 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
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[DOT 2017] Differentiated Receptor Pharmacology of Imipridone ONC201: The First DRD2 Antagonist in Clinical Development for Oncology
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[DOT 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
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[EULAR 2017] Systems-Based Investigation of the Anti-Immunogenic Potential of DMARDs for Rheumatoid Arthritis Using Human Primary Cell-Based BioMAP® Phenotypic Profiling
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[WPC 2017] Phenotypic Profiling in Human Primary Cell-Based Cell Systems Elucidates Mechanisms of Skin Irritation
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[WPC 2017] Single Donor KILR® CD16 Effector Cells to Drive Robust and Reproducible ADCC and T Cell Redirection
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[PEGS 2017] Single Donor KILR® CD16 Effector Cells to Drive Robust and Reproducible ADCC and T Cell Redirection
Download as PDF
[PEGS 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[PEGS 2017] Immune Checkpoint Inhibitor Profiling and Biomarker Identification Using Human Primary Cell BioMAP® Oncology Systems
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[ITOC 2017] Phenotypic Human Primary Cell-Based Tumor Microenvironment Models for Evaluation of Drug Combination for Immune Oncology
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[ICI 2017] Immune Checkpoint Inhibitor Profiling and Biomarker Identification Using Human Primary Cell BioMAP Oncology Systems
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[ICI 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
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[SOT 2017] Phenotypic Profiling in Human Primary Cell-Based Systems Provides Mechanistic Insight into the Cardiotoxicity of Tyrosine Kinase Inhibitors
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[Biologics Biosimilars Congress 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
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[Biologics Biosimilars Congress 2017] Specifically Measure Target Cell Death in a Co-Culture with ImmuneCells Through a Non-Radioactive, Dye-Free Cytotoxicity Assay
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[BEBPA USA 2017] Qualified, Fit-for-Purpose Bioassays for Liraglutide and Exenatide as Frozen Ready-to-Use Cells
Download as PDF
[BEBPA USA 2017] Ready-to-Use Potency Assays for Bevacizumab, Aflibercept, & Ranibizumab
Download as PDF
[BEBPA USA 2017] Development and Evaluation of a Novel Bioassay for Denosumab Activity
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[BEBPA USA 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[Advances in Drug Discovery 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
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[Advances in Drug Discovery 2017] A Duplexed Calcium and β-Arrestin Assay Protocol for Human Histamine H1 Receptor PathHunter CHO-K1 HRH1 β-Arrestin Cell Line
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[Biologics Biosimilars Congress 2017] Phenotypic Human Primary Cell-Based Tumor Microenvironment Models for Evaluation of Drug Combinations for Immune Oncology
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[SLAS 2017] CAR-T Cell Screening in Tumor Spheroids Using Corning Spheroid Microplates
Download as PDF
[SLAS 2017] Specifically Measure Target Cell Death in a Co-Culture with Immune Cells Through a Non-Radioactive, Dye-Free Cytotoxicity Assay
Download as PDF
[SLAS 2017] InCELL Pulse™: A Novel Cellular Target Engagement Assay Platform for Drug Discovery
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[SLAS 2017] Quantifying GPCR Signaling Bias: A Simple Approach to Quantify Selectivity and Agonist Bias
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[SLAS 2017] A Duplexed Calcium and β-Arrestin Assay Protocol for Human Histamine H1 Receptor PathHunter CHO-K1 HRH1 β-Arrestin Cell Line
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[DOT 2016] InCELL Pulse™: A Novel Cellular Target Engagement Assay Platform for Drug Discovery
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[2016 ELRIG Conference Poster] A Duplexed Calcium and β-Arrestin Assay Protocol for Human Histamine H1 Receptor PathHunter CHO-K1 HRH1 β-Arrestin Cell Line
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[2016 DOT Conference Poster] Interrogating Allosteric Interactions Using Multiple Readouts for GPCRs
Download as PDF
[2016 IRA Conference Poster] Building Better Cell-Based Assays for Interleukins and Their Receptors
Download as PDF
[2016 XXIV National Medicinal Chemistry] Interrogating Allosteric Interactions Using Multiple Readouts for GPCRs
Download as PDF
Phenotypic Profiling in BioMAP® Human Primary Cell Systems Identifies a Tox Alert Signature for Skin Irritation
Download as PDF
[2016 PEGS Conference] Novel, Improved Cell-based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Download as PDF
[2016 PEGS Conference] Specifically Measure Target Cell Death in a Co-Culture with Immune Cells Through a Non-Radioactive, Dye-free Cytotoxicity
Download as PDF
Phenotypic Human Primary Cell-based Tumor Microenvironment Models for Evaluation of Drug Combinations for Immune Oncology
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Improved Cell-Based Assays To Assess Therapeutic Molecules Against Immune Checkpoint Receptors Such As PD-1, PD-L1 And PD-L2
Download as PDF
[2016 Biopharmaceutical Symposium] Rapidly Develop Simple Potency Assays for Interleukins & Their Receptors
Download as PDF
[2016 Biopharmaceutical Symposium] Ready-to-use potency assays for anti-VEGF drugs such as Bevacizumab
Download as PDF
[2016 SLAS Conference Poster] Phenotypic Characterization of CFTR Drugs, VX-770 and VX-809, in BioMAP® Human Primary Cell Systems Connects Target Biology to Disease Mechanisms
Download as PDF
[2016 SLAS Conference Poster] Improved Cell-Based Assays To Assess Therapeutic Molecules Against Immune Checkpoint Receptors Such As PD-1, PD-L1 and PD-L2
Download as PDF
[2015 BEBPA Conference Poster] Rapidly Develop Simple Potency Assays for Interleukins & Their Receptors
Download as PDF
[2015 BEBPA Conference Poster] Ready-to-use potency assays for anti-VEGF drugs like Bevacizumab
Download as PDF
Quantifying Signaling Bias: A Simple Approach to Quantify Functional Selectivity and Agonist Bias
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Novel Trafficking Assays For Pharmacochaperone Discovery Using Enzyme Fragment Complementation Applied To CFTR-ΔF508
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Utilisation of the InCELL Hunter™ Target Engagement Cell-Based Assay for Profiling of ULK1 Inhibitors
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Elucidating Mechanisms of Toxicity Using Human Primary Cell Systems
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[2015 WCI Conference] Predicting Drug-induced Skin Rash Using BioMAP Human Primary Cell-based Systems
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A novel dye-free cytotoxicity assay to selectively measure target cell death in ADCC, CDC CAR-T or T-cell activation assays
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[2015 WCI Conference] Measuring Receptor Dimerization To Create Functional Cell-Based Assays for ~85% of the Interleukin Receptor Family
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Simple, Reproducible & Robust Bioassays In Cryopreserved Ready-To-Assay Format
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Quantifying Signaling Bias: A Simple Approach to Quantify Functional Selectivity and Agonist Bias
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Advances in tools to compare potency, efficacy, safety & quality of follow-on biologics or biosimilars
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[2015 NAb Conference Poster] Robust and Simple Potency and NAb Bioassays for Avastin® Biosimilar Development
Download as PDF
[2015 SOT Conference Poster] Elucidating Mechanisms of Cardiovascular Toxicity Using Phenotypic Data from BioMAP Human Primary Cell Systems
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[2015 Bioassay Conference] Simple, Reproducible & Robust Bioassays in Cryopreserved Ready-To-Assay Format
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Analysis of α-PD-1, α-PD-L1 and α-CTLA-4 Immune Checkpoint Antibodies in Human Primary Cell BioMAP Oncology Systems
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Elucidating Mechanisms of Toxicity Using Phenotypic Data from Human Primary Cell Systems – a Chemical Biology Approach for Thrombosis-Related Side Effects
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[2015 SLAS Conference Poster] Novel Trafficking Assays for Pharmacochaperone Discovery Using Enzyme Fragment Complementation
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[2015 SLAS Conference Poster] BioMAP® Human Primary Cell Systems for Improving Drug Discovery and Development
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[2015 SLAS Conference Poster] Interrogating Allosteric interactions Using Multiple Readouts for GPCRs
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[2014 FAST Conference Poster] Effects of Bromodomain Inhibitors on Renal and Pulmonary Fibrosis
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[2014 ACR Conference Poster] Profiling 14-3-3η in Human Primary Cell Based Disease Models Reveals a Unique Pro-Inflammatory Phenotypic Signature Consistent with RA-Inflammation Biology
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[2014 ACR Conference Poster] Analysis of Anakinra in Primary Human Cell Systems Reveals an In Vitro Signature for Skin-related Side Effects
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Development of Simple, Robust Bioassays for Biosimilar & Biobetter Development
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GLP1 NAb Assay: A Case Study for Simple, Serum-tolerant Cell-based Assays to Detect Neutralizing Antibodies to Biosimilar and Bioinnovator drugs
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Novel Trafficking Assays for Pharmacochaperone Discovery Using Enzyme Fragment Complementation
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[AOM_RA-Infl_Paris] BioMAP® Systems Integrate Human Biology and Drug Discovery To Enable The Development of Safer and More Effective Anti-inflammatory Therapies
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[2014 World Pharma Congress] Phenotypic Screening of Compounds and Drug Combinations in BioMAP® Oncology Systems Reveals Divergent Effects on Clinically-relevant Biomarkers
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[2014 PEGS Conference] Development of Novel Cell-based Assays to Detect Neutralizing Antibodies to Therapeutic Biologics
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[2014 PEGS Conference] Validated Bioassays for Potency, Stability and Lot Release Testing of Biopharmaceuticals
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[2014 PEGS Conference] Detection of EGFR, HER2, HER3 and HER4 Hetero- and Homodimerization Using EFC-based Cellular Assays
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[2014 DDC Conference] Rational design of dual kinase-bromodomain inhibitors for therapeutic polypharmacology
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[2014 AACR Poster] Dual kinase/bromodomain inhibitors for rationally designed polypharmacology
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[2014 AACR Poster] Detection of EGFR, HER2, HER3 and HER4 Hetero- and Homodimerization Using EFC-based Cellular Assays
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Predictive Models for Mechanism-of-Action Classification of Chemicals Using Phenotypic Data
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In Vitro Bioactivity in ToxCast Assays for Fruit and Vegetable Extracts
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Predicting Toxic and Therapeutic Mechanisms of the ToxCast Chemical Library by Phenotypic Screening
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Understanding Mechanisms of Drug-Induced Liver Injury Using Primary Human Cell and Co-culture Systems
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The application of EFC technology to study forward trafficking of GPCRs
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[2013 Society of Toxicology Poster] - Phenotypic Approaches Defining Toxicity Mechanisms
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Primary Human Cell BioMAP® Profiling of Methotrexate, Tocilizumab, Adalimumab, and Tofacitinib
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Detection of Cytokine and Growth Factor Receptor Dimerization Using Enzyme Fragment Complementation
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Detection of Endogenous Ligand Bias: A Case Study Using the Chemokine Receptor Family
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BioMAP® Primary Human Cell Systems for Improving Drug Discovery and Development
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Validated Cell-Based Assays for Rapid Screening and Functional Characterization of Therapeutic Monoclonal Antibodies
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The Druggable GPCRome
The Human Bromodomain Family
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Validated Cell-Based Assays for Rapid Screening and Functional Characterization of Therapeutic Monoclonal Antibodies
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BROMOscan high throughput, quantitative ligand binding assays identify best in class bromodomain inhibitors from a screen of mature compounds thought to specifically target other protein classes
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A Novel Assay Platform for the Detection of Kinase-Inhibitor Binding in Intact Mammalian Cells
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Novel Assays and Human Model Systems for Epigenetic Drug Discovery
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Mix-and-Read Assays For Regulated Ubiquitination & Degradation of Proteins Using PathHunter® Technology
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InCELL Hunter™: A Novel Cellular Assay Platform for the Direct Measurement of Compound Binding to Intracellular Targets in Intact Mammalian Cells
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Multi-Parameter GPCR Screening: An Essential Tool for Uncovering GPCR Mutant Phenotypes
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Phenotypic Approaches Defining Toxicity Mechanisms
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BROMOscan high throughput, quantitative ligand binding assays identify best in class bromodomain inhibitors from a screen of mature compounds thought to specifically target other protein classes
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scanKINETIC: A broadly applicable tool for the kinetic characterization of interactions between small molecule inhibitors and protein targets from the kinase and bromodomain families
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A Novel Assay Platform for the Detection of Kinase-Inhibitor Binding in Intact Mammalian Cells
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The Human Kinome
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Utilization of PathHunter® Arrestin Cell Lines for Detection of Arrestin Biased Ligands and Compound Pharmacology Distinct from Second Messengers
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Unique Properties of PathHunter® β-Arrestin Assays for GPCR Antagonist Discovery and Characterization
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Ultrasensitive, 3456 or 1536-Well Miniaturization-Friendly Chemiluminescent Detection of PathHunter® Cell-Based GPCR and Kinase Assays
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PathHunter® β-Arrestin Assays: Determination of Pharmacology Differences Between Human and Ortholog GPCRs
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PathHunter® β-Arrestin Assays as a Universal Tool For Orphan GPCR Analysis
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PathHunter® Cell-Based Kinase Assays: A Portfolio of HTS-friendly Cytoplasmic or Receptor Tyrosine Kinase Assays for Small Molecule Inhibitors as well as Monoclonal Antibodies
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Novel Trafficking Assays for Pharmacochaperone Discovery Using Enzyme Fragment Complementation
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New Cell-Based Kinase Assays for TrkA and Other Receptor Tyrosine Kinases using PathHunter™ Protein-Protein Interaction Technology
Download as PDF
HitHunter® cAMP and cAMP Hunter™ Cell Line: Your Solution for Use with High Serum Samples, Difficult Gi Targets and Identification of Allosteric Modulators
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Functional Whole-cell Assays for Tyrosine Phosphorylation Using PathHunter® Technology
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Functional Receptor Tyrosine Kinase Assays for Antibody therapeutics Using PathHunter® Technology
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Dual Purpose Cell Lines for Analysis of GPCR/Arrestin Interaction using PathHunter® and Natural Gq-Coupling Using the Improved Calcium No-WashPLUS (CaNWPLUS) Kit
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Cell-Based Assays for G-Protein Independent Signaling Using Arrestin Binding and Endocytosis
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Application of the PathHunter® Protein Interaction Assay to Receptor Tyrosine Kinases (RTKs): Developing a Non-Antibody One-Step Cell-Based Kinase Activity
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ADP Hunter™ Plus: A Rapid, Quantitative HTS Assay for GDP and UDP
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A Wide Range of Compound Efficacies Revealed Using PathHunter® Arrestin Assays
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A High Sensitivity Assay for Kinetic Analysis of Kinases and ATPases Based on Measurement of ADP Accumulation
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[DOT 2018] Development of High Throughput Cellular Thermal Shift Assays: Cellular Mechanistic Assays in Early Drug Discovery
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[Immuno-Oncology Summit 2018] Evaluating Immuno-Oncology (I-O) Potential of Compounds and Combinations Using In Vitro Human TME Models
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[PEGS 2018] Simplifying Implementation of Robust Bioassays in Development to QC Lot Release
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[DDC 2018] Binding and Functional Analysis - Complementary Approaches in Safety Pharmacology Using GPCRs
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[US-BEBPA 2018] Seamless Implementation of Robust and Simple Bioassays
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[US-BEBPA 2018] Generation of Cryopreserved (Ready-to-Use) Cells for Bioassays
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[Biologics 2018] Seamless Implementation of Robust and Simple Bioassays
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[SLAS 2018] Large Scale Profiling in Human Primary Cell-Based Phenotypic Assays Identifies Novel Outcome Pathways for Drug Efficacy in Cardiovascular Disease
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[WCBP 2018] Seamless Implementation of Robust and Simple Bioassays
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[WPC 2017] Human-Based Phenotypic Profiling Uncovers Mechanisms of Toxicity
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[Advances Immuno-Oncology 2017] Evaluating Immuno-Oncology Potential of Compounds and Combinations in BioMAP®
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[CASSS 2017] Robust and Reproducible ADCC and T Cell Redirection with CD16-Engineered Effector Cells
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[PEGS 2017] Enabling Technologies for Development and Optimization of Bi-Specific Antibodies for T Cell Redirection
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[ICI 2017] Evaluating Immuno-Oncology Potential of Compounds and Combinations in BioMAP
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[Biologics Biosimilars Congress 2017] Harnessing the Complexity of the Human Tumor Microenvironment to Guide Decisions in Discovery and Combinations
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[BEBPA USA 2017] Optimizing and Qualifying Bioassays for Biosimilars, Biobetters, and Innovator Drugs
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[Advances in Drug Discovery 2017] Enabling Cancer Immunotherapy: From Target to Phenotype
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[SLAS 2017] Combining Target-Based and Phenotypic Assays for Successful Drug Repurposing
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[2015 WCI Conference] Identification of Immunomodulatory and Anti-Fibrotic Actions of Nintedanib and Pirfenidone Using BioMAP® Human Primary Cell-based Disease Models
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Modelling the Host-‐Tumour Stromal and Vascular Microenvironments to Support Compound Screening and Therapeutic Development
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Extracting Meaning from Complex Data: Predictive Models for Mechanism of Action Classification from Phenotypic Assay Data – Application to Phenotypic Drug Discovery
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Primary Human Cell BioMAP® Profiling of Methotrexate, Tocilizumab, Adalimumab, and Tofacitinib Reveals Different Mechanisms of Action With Distinct Phenotypic Signatures
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The BioMAP® Platform of Primary Human Cell Systems for Phenotypic Drug Discovery and Development – Lessons Learned
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[DiscoverX/SGC Technology Symposium] - Epigenetic Target Identification for Musculoskeletal Disease
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[DiscoverX/SGC Technology Symposium] - Cracking the Histone Code? Development of small-molecule inhibitors of the bromodomain acetyl-lysine interaction
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[DiscoverX/SGC Technology Symposium] - Application of computational approaches to accelerate bromodomain drug discovery
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[DiscoverX/SGC Technology Symposium] - Integrated Solution for Epigenetic Drug Discovery and Development
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[DiscoverX/SGC Technology Symposium] - Targeting Bromodomains – BET and the wider target class
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[DiscoverX/SGC Technology Symposium] - Assays and Probes for Epigenetic Targets
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[DiscoverX/SGC Technology Symposium] - Selective Targeting of Protein Interactions Mediated by Epigenetic Effector Domains
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To B or Not To B: Phenotypic Profiling BTK Inhibitors in BioMAP® Systems
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Cell-based Receptor Tyrosine Kinase Screening Reloaded - Development of a new cellular assay system for a target protein so far resistent against HTS formats
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Using DiscoverX’s ADP QuestTM for Academic Screening of Novel Kinases
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[DiscoverX/SGC Technology Symposium] - Profiling Compounds in Primary Human Cell BioMAP Systems for Drug Discovery and Therapeutic Development in Inflammation and Cancer
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[User Manual] PathHunter® IL17RA/IL17RC Dimerization Bioassay Kit
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[User Manual] PathHunter® Checkpoint Assay - TNF Receptor Superfamily (TNFRSF)
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[User Manual] InCELL Hunter™ Target Engagement Cell Lines
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[User Manual] PathHunter® Sargramostim Bioassay Kit
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[User Manual] PathHunter® PD-1 Signaling Bioassay Kit
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[User Manual] PathHunter® Anakinra Bioassay Kit
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[User Manual] PathHunter® IL6R/IL6ST Bioassay Kit
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[User Manual] PathHunter® U2OS MC4R Bioassay Kit
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[User Manual] KILR® CD16 Effector Cells
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[User Manual] cAMP Hunter™ Follitropin Alfa Bioassay Kit
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[Technical Bulletin] Updated Cell Culture Protocol and Handling Procedure
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[User Manual] cAMP Hunter™ Exenatide Bioassay Kit
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[User Manual] cAMP Hunter™ Liraglutide Bioassay Kit
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[User Manual] PathHunter® IL-2 Bioassay Kit
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[User Manual] InCELL Hunter™ Target Engagement Assay Kit
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[User Manual] PathHunter® Pertuzumab Bioassay Kit
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[User Manual] PathHunter® CHO-K1 VIPR2 Bioassay Kit
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[User Manual] ProLabel® and ProLink™ Mammalian Cloning Vectors
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[User Manual] PathHunter® FGFR4-Beta-Klotho Bioassay Kit
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[User Manual] InCELL Pulse™ Target Engagement Starter Kit
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[User Manual] InCELL Pulse™ Cellular Target Engagement Assays
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[User Manual] InCELL Detection Kit
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[User Manual] PathHunter® Panitumumab Bioassay Kit
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[User Manual] PathHunter® Bioassay Detection Kit
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[User Manual] PathHunter® IGF1R Bioassay Kit
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[User Manual] PathHunter® TrkC Bioassay Kit
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[User Manual] PathHunter® EA Parental Cell Lines
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[User Manual] PathHunter® Co-Stimulatory Checkpoint Assay
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[User Manual] PathHunter® β-Arrestin2 Retroparticles
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[User Manual] PathHunter eXpress Degradation Assays
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[User Manual] KILR® Retroparticles For Cytotoxicity Assays
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[User Manual] PathHunter® IL1RL1/IL1RAP Dimerization Bioassay Kit
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[User Manual] PathHunter® PTH Bioassay Kit
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[User Manual] cAMP Hunter™ Teriparatide Bioassay Kit
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[User Manual] PathHunter® Checkpoint Signaling Assay - Immunoglobulin Superfamily (IgSF)
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[User Manual] PathHunter® Exendin-4 Bioassay Kit
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[User Manual] PathHunter® Bioassay ED Detection Kit
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[User Manual] cAMP Hunter™ Exendin-4 Bioassay Kit
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[User Manual] PathHunter® Insulin Bioassay Kit
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[User Manual] KILR® Detection Kit
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[User Manual] KILR® Cytotoxicity Assay−Adherent Target Cell Lines
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[User Manual] KILR® Assay for Suspension Cell Lines
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[User Manual] PathHunter® Ranibizumab Bioassay Kit
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[User Manual] PathHunter® Aflibercept Bioassay Kit
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[User Manual] PathHunter® GLP1 (7-37) Bioassay Kit
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[User Manual] PathHunter® Epoetin Alfa Bioassay Kit
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[User Manual] PathHunter® Insulin Lispro Bioassay Kit
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[User Manual] PathHunter® Insulin Glargine Bioassay Kit
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[User Manual] PathHunter® Bevacizumab Bioassay Kit
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[User Manual] PathHunter® Human Growth Hormone Bioassay Kit
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[User Manual] PathHunter® Darbepoetin Alfa Bioassay Kit
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[User Manual] PathHunter® Dimerization Bioassay Kit
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[User Manual] PathHunter® Receptor Tyrosine Kinase Bioassay Kit
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[User Manual] PathHunter® Cytokine Receptor Bioassay Kit
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[User Manual] cAMP Hunter™ GPCR Bioassay Kit
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[User Manual] PathHunter® GPCR Bioassay Kit
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[User Manual] HitHunter® cAMP Assay for Biologics
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[User Manual] HitHunter® cAMP Assay for Small Molecules
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[User Manual] InCELL Hunter™ eXpress Protein Binding Assays
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[User Manual] PathHunter® eXpress Cytosolic Tyrosine Kinase Activity Assay Kit
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[User Manual] PathHunter® eXpress Nuclear Translocation Assays
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[User Manual] PathHunter® Pharmacotrafficking Assays
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[User Manual] PathHunter® Dimerization Assay
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[User Manual] Native Calcium GPCR Assays
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[User Manual] PathHunter® eXpress Receptor Tyrosine Kinase Internalization Assay Kit
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[User Manual] PathHunter® eXpress Receptor Tyrosine Kinase Activity Assay Kit
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[User Manual] PathHunter® eXpress Dimerization Assay Kit
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[User Manual] PathHunter® NHR Assay
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[User Manual] InCELL Hunter™ eXpress Kinase Binding Assays
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[User Manual] InCELL Hunter™ eXpress Histone Methyltransferase Assays
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[User Manual] InCELL Hunter™ eXpress Bromodomain Assays
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[User Manual] PathHunter® Receptor Tyrosine Kinase Internalization Assays
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[User Manual] PathHunter® Receptor Tyrosine Kinase Activity Assay
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[User Manual] PathHunter® Cytosolic Tyrosine Kinase Functional Assay
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[User Manual] PathHunter® ProLabel®/ProLink™ Detection Kit
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[User Manual] PathHunter® Pathway Assay
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[User Manual] HitHunter® cGMP Assay
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[User Manual] Calcium No WashPLUS Assay Kit
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[User Manual] InCELL Hunter™ Bromodomain Cell-Based Assay
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[User Manual] ProLink™ Detection Kit
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[User Manual] PathHunter® ProLabel Detection Kit
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[User Manual] PathHunter® Flash Detection Kit
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[User Manual] PathHunter® EA Detection Kit
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[User Manual] PathHunter® β-Arrestin Assay for GPCR Cell Lines
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[User Manual] PathHunter® Total GPCR Internalization Assay
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[User Manual] PathHunter® Receptor Tyrosine Kinase Functional Assay
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[User Manual] PathHunter® GPCR Explorer Kit
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[User Manual] PathHunter® β-Arrestin eXpress GPCR Assay
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[User Manual] PathHunter® eXpress Total GPCR Internalization Assay
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[User Manual] PathHunter® eXpress Receptor Tyrosine Kinase Functional Assay Kit
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[User Manual] PathHunter® eXpress Nuclear Hormone Receptor Assay Kit
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[User Manual] PathHunter® eXpress Cytosolic Tyrosine Kinase Functional Assay Kit
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[User Manual] PathHunter® eXpress Activated GPCR Internalization Assay
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[User Manual] PathHunter® Detection Kit
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[User Manual] PathHunter® Activated GPCR Internalization Assay
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[User Manual] PathHunter® Cytosolic Tyrosine Kinase Activity Assay
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[User Manual] PathHunter® Bcl2–Bim Protein Interaction Assay
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[User Manual] EFC BlocDetect Kit
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[User Manual] cAMP Hunter™ Gs and Gi Cell Lines
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[User Manual] cAMP Hunter™ eXpress GPCR Assays
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BioMAP® T Cell Autoimmune Panel Sample Report
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BioMAP® Colorectal Cancer (CRC) Panel Sample Report
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BioMAP® Diversity PLUS Sample Report
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gpcrSCAN Sample Report
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scanMAX Sample Report
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gpcrMAX Sample Report
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