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Document Resource Library

Our online document resource library contains our most popular resources, tools and product literature, and are available for immediate download. To request printed copies, please select desired materials below and enter your address details at the bottom of the page.

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Implementing MOA-Reflective ADCC Assays using Ready-to-Use KILR Target and Effector Cells from Screening to Lot Release

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Automating Cell-Based Bioassay on Tecan®’s Fluent Automation Workstation: Measuring PD-1 Signaling

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Rapid Generation of Highly Potent and Selective Kinase HIT

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Case Study: Implementing Robust & Reproducible KILR® Ready-to-Use Bioassays from Screening to Lot Release: Applications for Measuring Direct Cytotoxic Cell Death

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eBook: Insights into GPCR Drug Discovery & Development – Exploring GPCR-Ligand Interactions & Signaling Pathways with Binding & Functional Assays

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Ligand Characterization of Mas-Related GPCR-X2 via Cell-Based Assays: Assessing the Regulation of Mast Cell Function and Implications in Safety Pharmacology

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HTS Rapid Generation of Highly Potent and Selective Kinase HIT Compounds

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Automating Cell-Based Bioassays on Tecan®’s Fluent Automation Workstation: Measuring β-Arrestin Recruitment of Cannabinoid Receptor 1

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Intracolonic Drug Delivery in Mice and Adolescent Rats with Surgically Implanted Catheters

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NASH Drug Discovery

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App Note: Automating a Cell-Based Target-Compound Assay for Methyltransferase and Bromodomain Proteins using the InCELL Hunter Platform

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App Note: InCELL Pulse Cellular Target Engagement Assays for Characterizing Novel Small Molecule Inhibitors of Oncogenic SHP2 Variants

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Case Studies: Evaluating Checkpoint Receptor Bioassays: Fit-For-Purpose Assays Intended for Potency Testing of Therapeutic Candidates in QC Lot Release

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[White Paper] Accelerating Immune Checkpoint Drug Discovery through Functional Cell-Based Assays

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Uncover Novel G-Protein or Arrestin-Biased Ligands Using a Suite of GPCR Signaling Cell-Based Assays: A Study of Biased Agonism on Opioid Receptors

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Quantify GPCR Endocytosis and Recycling with PathHunter® GPCR Internalization Assays – Analyzing Therapeutics for Opioid and Cholecystokinin Receptors

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White Paper: Profiling Oncology Drug Candidates Through Complementary in vitro Assays and in vivo Models to Better Understand Their Potential Clinical Applications

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White Paper: Models of Human Tumor Microenvironments Created for Phenotypic Profiling Reveal the Promise – and Challenge – of IDO Inhibitors

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White Paper: The New World of GPCR Allosteric Modulation

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White Paper: Phenotypic Profiling Identifies Biomarkers and Mechanisms of Toxicity

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SAFETYscan Case Study

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CAR-T Cell Screening in Tumor Spheroids using Corning® Spheroid Microplates and the KILR® Cytotoxicity Assay

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InCELL Pulse™ Target Engagement Kinase Reference Set

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A Simple & Powerful Cell-Based Assay to Quantify Specific Target Cell Death by Antibody-Dependent Cellular Phagocytosis (ADCP)

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[White Paper] Accelerating Biosimilar & Biobetter Drug Development: Ready-to-Use, Cell-Based Assays for Potency and Lot Release Testing

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BioSeek: Secondary Activity of an Adrenergic Receptor Antagonist Bridging the Gap from In Vitro to In Vivo

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BioSeek: Explaining a Clinical Adverse Event - Bridging the Gap from In Vitro to In Vivo

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BioSeek: Economic Impact of BioMAP® Profiling - Bridging the Gap from In Vitro to In Vivo

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BioSeek: Differentiating p38MAPK Inhibitors - Bridging the Gap from In Vitro to In Vivo

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Comprehensive analysis of kinase inhibitor selectivity

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Rapid Quantification of Bioactive Ligands in Serum and Human Plasma Using PathHunter® eXpress β-Arrestin GPCR Assays

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Evaluation of a New Intracellular Calcium Fluorescent Reagent Using the FDSS6000

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Enabling Functional Therapeutic Antibody Research Using PathHunter® β-Arrestin Technology

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Discovery of Novel G-Protein or Arrestin-Biased Ligands Using a Suite of GPCR Signaling Platforms

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Chemiluminescent cAMP Detection Using DiscoverX HitHunter® Kits Compared With TR-FRET Assays

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Propelling GPCR drug discovery with innovative products and services

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New Momentum for Kinase Drug Discovery

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Faster Chemiluminescent cAMP Detection by HitHunter® cAMP XS+ on the SpectraMax L Luminescence Microplate Reader

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