There is a tremendous need to generate therapeutics targeting metabolic and gastrointestinal diseases. By targeting GPCRs, glucagon-like peptide (GLP-1 and GLP-2) receptors, therapeutics can be developed to address these globally prevalent medical disorders. In particular, engineered recombinant agonist analogues targeting the GLP-1 receptor are FDA approved for managing type 2 diabetes, obesity and body weight disorders, while GLP-2 analogues have been under therapeutic focus for the treatment of short bowel syndrome, a serious unmet medical disorder. Several other novel GLP analogues, including biosimilar and biobetters, are in clinical development; however, existing assays for characterising their mechanism-of-actions (MOAs) are complex and require extensive development time.
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Event capacity:
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N/A
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Event location:
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Event date:
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3/22/2023, 8:00 AM - 8:00 PM
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