Search results: “ATP”

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Publications Development of Selective Phosphatidylinositol 5‑Phosphate 4‑Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode

Phosphatidylinositol 5-phosphate 4-kinases (PI5P4Ks) are emerging as attractive therapeutic targets in diseases, such as cancer, immunological disorders, and neurodegeneration, owing…

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Scientific Posters A High Sensitivity Assay for Kinetic Analysis of Kinases and ATPases Based on Measurement of ADP Accumulation

DiscoveRx has developed a unique assay technology based on an enzyme-coupled detection system that measures ADP accumulation which has been…

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Scientific Posters ADP Hunter™ Plus: A Rapid, Quantitative HTS Assay for GDP and UDP

There are numerous assays available to measure the activity of enzymes involved in the transfer of a phosphate from ATP…

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Scientific Posters A Novel Assay Platform for the Detection of Kinase-Inhibitor Binding in Intact Mammalian Cells

Assays that directly detect compound binding inside cells can be of great utility in translating in vitro data to more…

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