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Mast cells play key roles in allergy, anaphylaxis/anaphylactoid reactions, and defense against pathogens/toxins. These cells contain cytoplasmic granules with a…
Read MoreBy suppressing gene transcription through the recruitment of corepressor proteins, B-cell lymphoma 6 (BCL6) protein controls a transcriptional network required…
Read MoreBiological activity of a biotherapeutic is a Critical Quality Attribute (CQA), which needs to be accurately measured by an appropriate…
Read MoreAs newer, cutting-edge therapeutic technologies emerge, an increasing need for rapid and reliable screening tools follows.
Read MoreA novel and growing modality in drug discovery has been the application of Targeted Protein Degradation (TPD). TPD involves the…
Read MoreLearn about several GPCR assays and which ones to use and why for your research and drug discovery and development…
Watch NowLearn how to easily detect target protein turnover induced by targeted degrader molecules, such as PROTACs (trademark of Arvinas). Discover…
Watch NowSPRINTer™ protein turnover biosensor assays overview. Keystone 2021 Poster Presentation. 5 min.
Watch NowThroughout early discovery and particularly for market release, biologic drug candidates require mechanism-of-action (MOA)-based functional, cellular assays as characterisation tools…
Watch NowAn assay platform that robustly and sensitively quantifies the kinetics of endogenous protein turnover and target engagement is crucial for…
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