Search results: “IL-17”

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Scientific Posters Advancing Therapeutics Targeting Inflammatory Cytokines with Functional Cell-based Assays

Case studies on the use of cell-based assays that monitor receptor dimerization and signaling reporter activation targeting IL-12, IL-23, IL-15,…

Scientific Posters Comprehensive & Fit-For-Purpose Solutions to Enable Drug Development for Cytokine Targets

Interleukins are known for their involvement in functioning of both the adaptive and innate immune systems. Interleukins direct immune cells…

Scientific Posters Phenotypic Characterization of CFTR Drugs, VX-770 and VX-809, in BioMAP® Human Primary Cell Systems Connects Target Biology to Disease Mechanisms

Cystic fibrosis (CF) patients have mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel that result in reduced…

Scientific Posters Detection of Cytokine and Growth Factor Receptor Dimerization Using Enzyme Fragment Complementation

Ligand-induced receptor dimerization is the first functional step in receptor activation, representing the most proximal, functional read-out for receptor activation.…

Presentations [Cytokines Summit 2022] Enabling Cytokine Therapeutic Development with Qualified, Functional Cell-Based Assays

Gaurav Agrawal, Ph.D.Scientific Development Manager Discover how cell-based assays and translational services accelerate cytokine-based immunotherapeutic development from early discovery to…