G-protein-coupled receptors (GPCRs) have varying and diverse physiological roles, transmitting signals from a range of stimuli, including light, chemicals, peptides,…
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G-protein-coupled receptors (GPCRs) have varying and diverse physiological roles, transmitting signals from a range of stimuli, including light, chemicals, peptides,…
Read MoreDiscoveRx® has pioneered a novel enzyme complementation system to monitor cellular events such as protein translocation, protein interactions, and degradation…
Read MoreDiscoveRx® has pioneered a novel enzyme complementation system to monitor cellular events such as protein translocation, protein interactions, and degradation…
Read MoreStriatal-enriched protein tyrosine phosphatase (STEP) is a brain-specific enzyme that regulates the signaling molecules that control synaptic plasticity and neuronal…
Read MoreCurrent therapies for chronic pain can have insufficient efficacy and lead to side effects, necessitating research of novel targets against…
Read MoreStrong genetic data link the Tyrosine kinase receptor B (TrkB) and its major endogenous ligand brain-derived neurotrophic factor (BDNF) to…
Read MoreSmall ubiquitin-like modifier (SUMO) is a member of a ubiquitin-like protein superfamily. SUMOylation is a reversible posttranslational modification that has…
Read MoreCell-based assays are useful for understanding cellular pathways; characterizing targets and their function; identifying, screening, and optimizing ligands or drugs…
Read MoreLearn how InCELL cell-based binding assays can be used to detect compound cell entry and engagement to specific targets including…
Watch NowLearn about PathHunter pharmacotrafficking assays to identify small molecule compounds that rescue disease relevant mutant membrane proteins like GPCRs, ion…
Watch NowExplore Functional Systems Driving GPCRs to the Forefront of Focused & Safe Therapeutics. Gain insights from industry experts on GPCR…
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