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GPCR Target List

View our complete list of GPCR Targets
FamilyGene Symbol ▲Common NameSpeciesCell LinesAssay Ready KitsService
VIP and PACAPADCYAP1R1Adenylate cyclase activating polypeptide receptor 1 (PAC1)HumanYesYesYes
AdenosineADORA1Adenosine receptor A1 (A1)HumanYes Yes
AdenosineADORA2AAdenosine receptor A2A (A2A)HumanYes Yes
AdenosineADORA2BAdenosine receptor A2B (A2B)HumanYesYesYes
AdenosineADORA3Adenosine receptor A3 (A3)HumanYesYesYes
AdrenoceptorsADRA1AAdrenergic receptor alpha 1A (α1A-adrenoceptor)HumanYes Yes
AdrenoceptorsADRA1BAdrenergic receptor alpha 1B (α1B-adrenoceptor)HumanYesYesYes
AdrenoceptorsADRA1D(82-572)Adrenergic receptor alpha 1D (α1D-adrenoceptor)HumanYes Yes
AdrenoceptorsADRA2AAdrenergic receptor alpha 2A (α2A-adrenoceptor)HumanYesYesYes
AdrenoceptorsADRA2BAdrenergic receptor alpha 2B (α2B-adrenoceptor)HumanYesYesYes
AdrenoceptorsADRA2CAdrenergic receptor alpha 2C (α2C-adrenoceptor)HumanYesYesYes
AdrenoceptorsADRB1Adrenergic receptor beta 1 (β1-adrenoreceptor)HumanYesYesYes
AdrenoceptorsADRB2Adrenergic receptor beta 2 (β2-adrenoreceptor)HumanYesYesYes
AdrenoceptorsADRB2(W158A)Adrenergic receptor beta 2 (β2-adrenoreceptor)HumanYesYesYes
AdrenoceptorsADRB3Adrenergic receptor beta 3 (β3-adrenoreceptor)HumanYesYesYes
AngiotensinAGTR1Angiotensin II receptor, type 1 (AT1)HumanYesYesYes
ApelinAGTRL1Apelin receptor (APJ)HumanYesYesYes
Vasopressin and OxytocinAVPR1AVasopressin receptor 1A (V1A)HumanYesYesYes
Vasopressin and OxytocinAVPR1BVasopressin receptor 1B (V1B)HumanYesYesYes
Vasopressin and OxytocinAVPR2Vasopressin receptor 2 (V2)HumanYesYesYes
Vasopressin and OxytocinAVPR2(S167T)Vasopressin receptor 2 (V2)HumanYes Yes
Class B OrphanBAI1Brain-specific angiogenesis inhibitor 1 (BAI1)HumanYes Yes
Class B OrphanBAI2Brain-specific angiogenesis inhibitor 2 (BAI2)HumanYesYesYes
Class B OrphanBAI3Brain-specific angiogenesis inhibitor 3 (BAI3)HumanYesYesYes
BradykininBDKRB1Bradykinin receptor B1 (B1)HumanYesYesYes
BradykininBDKRB2Bradykinin receptor B2 (B2)HumanYesYesYes
BombesinBRS3Bombesin receptor, subtype 3 (BB3)HumanYesYesYes
Complement peptideC3AR1Complement component 3a receptor 1 (C3A)HumanYesYesYes
Complement peptideC5AR1Complement component 5a receptor 1 (C5A)HumanYesYesYes
Complement peptideC5L2G-Protein Coupled Receptor 77 (C5L2)HumanYesYesYes
CalcitoninCALCRCalcitonin receptor (CT)HumanYesYesYes
CalcitoninCALCRL-RAMP1Calcitonin receptor-like (Calcitonin receptor-like receptor)HumanYesYesYes
CalcitoninCALCRL-RAMP2Calcitonin receptor-like (Calcitonin receptor-like receptor)HumanYesYesYes
CalcitoninCALCRL-RAMP3Calcitonin receptor-like (Calcitonin receptor-like receptor)HumanYesYesYes
CalcitoninCALCR-RAMP2Calcitonin receptor (CT)HumanYesYesYes
CalcitoninCALCR-RAMP3Calcitonin receptor (CT)HumanYesYesYes
Calcium sensingCASRCalcium-sensing receptor (CaS)HumanYes Yes
CholecystokininCCKARCholecystokinin A receptor (CCK1)HumanYesYesYes
CholecystokininCCKBRCholecystokinin B receptor (CCK2)HumanYesYesYes
ChemokineCCR1Chemokine (C-C motif) receptor 1 (CCR1)HumanYesYesYes
ChemokineCCR10Chemokine (C-C motif) receptor 10 (CCR10)HumanYesYesYes
ChemokineCCR2Chemokine (C-C motif) receptor 2 (CCR2)HumanYesYesYes
ChemokineCCR3Chemokine (C-C motif) receptor 3 (CCR3)HumanYesYesYes
ChemokineCCR4Chemokine (C-C motif) receptor 4 (CCR4)HumanYesYesYes
ChemokineCCR5Chemokine (C-C motif) receptor 5 (CCR5)HumanYesYesYes
ChemokineCCR6Chemokine (C-C motif) receptor 6 (CCR6)HumanYesYesYes
ChemokineCCR7Chemokine (C-C motif) receptor 7 (CCR7)HumanYesYesYes
ChemokineCCR8Chemokine (C-C motif) receptor 8 (CCR8)HumanYesYesYes
ChemokineCCR9Chemokine (C-C motif) receptor 9 (CCR9)HumanYesYesYes
ChemokineCCRL1chemokine (C-C motif) receptor-like 1 (CCRL1)HumanYes Yes
ChemokineCCRL2Chemokine (C-C motif) receptor-like 2 (CCRL2)HumanYesYesYes
Lysophospholipid (S1P)cEDG5Sphingosine 1-phosphate receptor 2 (cS1P2)CanineYes Yes
Class A OrphancGPR91Succinic receptor, canine (cSUCNR1 )CanineYes  
AcetylcholineCHRM1Cholinergic receptor, muscarinic 1 (M1)HumanYesYesYes
AcetylcholineCHRM2Cholinergic receptor, muscarinic 2 (M2)HumanYesYesYes
AcetylcholineCHRM3Cholinergic receptor, muscarinic 3 (M3)HumanYesYesYes
AcetylcholineCHRM4Cholinergic receptor, muscarinic 4 (M4)HumanYesYesYes
AcetylcholineCHRM5Cholinergic receptor, muscarinic 5 (M5)HumanYesYesYes
ChemerinCMKLR1Chemokine-like receptor 1 (CMKLR1)HumanYesYesYes
CannabinoidCNR1Cannabinoid receptor 1 (CB1)HumanYesYesYes
CannabinoidCNR2Cannabinoid receptor 2 (CB2)HumanYesYesYes
Corticotropin-releasing factorCRHR1Corticotropin releasing hormone receptor 1 (CRF1)HumanYesYesYes
Corticotropin-releasing factorCRHR2Corticotropin releasing hormone receptor 2 (CRF2)HumanYesYesYes
ProstanoidCRTH2prostaglandin D2 receptor 2 (PTGDR2)HumanYesYesYes
ChemokineCX3CR1Chemokine C-X3-C receptor 1 (CX3CR1)HumanYesYesYes
ChemokineCXCR1Chemokine (C-X-C motif) receptor 1 (CXCR1)HumanYesYesYes
ChemokineCXCR2Chemokine (C-X-C motif) receptor 2 (CXCR2)HumanYesYesYes
ChemokineCXCR3Chemokine (C-X-C motif) receptor 3 (CXCR3)HumanYesYesYes
ChemokineCXCR4Chemokine (C-X-C motif) receptor 4 (CXCR4)HumanYesYesYes
ChemokineCXCR5Burkitt lymphoma receptor (CXCR5)HumanYesYesYes
ChemokineCXCR6Chemokine (C-X-C motif) receptor 6 (CXCR6)HumanYesYesYes
ChemokineCXCR7Chemokine (C-X-C motif) receptor 7 (CXCR7)HumanYesYesYes
Chemokinecyno CXCR1Chemokine (C-X-C motif) receptor 1 (CXCR1)Macaca fascicularisYesYesYes
Chemokinecyno CXCR2Chemokine (C-X-C motif) receptor 2 (CXCR2)Macaca fascicularisYesYesYes
Free fatty acidcyno GPR120G-protein coupled receptor 120 (FFA4)Macaca fascicularisYes Yes
Leukotriene CYSLTR2Cysteinyl leukotriene receptor 2 (CYSLT2)HumanYes Yes
ChemokineDARCDuffy blood group, chemokine receptor (FY)HumanYesYesYes
DopamineDRD1Dopamine receptor D1 (D1)HumanYesYesYes
DopamineDRD2LDopamine Receptor D2 (long isoform) (D2L)HumanYesYesYes
DopamineDRD2SDopamine Receptor D2 (short isoform) (D2S)HumanYesYesYes
DopamineDRD3Dopamine Receptor D3 (D3)HumanYesYesYes
DopamineDRD4Dopamine Receptor D4 (D4)HumanYesYesYes
DopamineDRD5Dopamine receptor D5 (D5)HumanYesYesYes
Class A OrphanEBI2G protein-coupled receptor 183 (GPR183)HumanYesYesYes
Lysophospholipid (S1P)EDG1Sphingosine 1-phosphate receptor 1 (S1P1)HumanYesYesYes
Lysophospholipid (LPA)EDG2Lysophosphatidic acid receptor 1 (LPA1)HumanYes Yes
Lysophospholipid (S1P)EDG3Sphingosine 1-phosphate receptor 3 (S1P3)HumanYesYesYes
Lysophospholipid (LPA)EDG4Lysophosphatidic acid receptor 2 (LPA2)HumanYesYesYes
Lysophospholipid (S1P)EDG5Sphingosine 1-phosphate receptor 2 (S1P2)HumanYesYesYes
Lysophospholipid (S1P)EDG6Sphingosine 1-phosphate receptor 4 (S1P4)HumanYes Yes
Lysophospholipid (LPA)EDG7Lysophosphatidic acid receptor 3 (LPA3)HumanYesYesYes
EndothelinEDNRAEndothelin receptor type A (ETA)HumanYesYesYes
EndothelinEDNRBEndothelin receptor type B (ETB)HumanYesYesYes
Protease activatedF2RCoagulation factor II (thrombin) receptor (PAR1)HumanYesYesYes
Protease activatedF2RL1Coagulation factor II (thrombin) receptor-like 1 (PAR2) (PAR2)HumanYesYesYes
Protease activatedF2RL3Coagulation factor II (thrombin) receptor-like 3 (PAR4) (PAR4)HumanYesYesYes
Free Fatty AcidFFAR1Free fatty acid receptor 1 (FFA1)HumanYes Yes
Free Fatty AcidFFAR2Free fatty acid receptor 2 (GPR43)HumanYes Yes
Free Fatty AcidFFAR3Free fatty acid receptor 3 (GPR41)HumanYesYesYes
FormylpeptideFPR1Formylpeptide receptor 1 (FPR1)HumanYesYesYes
FormylpeptideFPR3Formyl peptide receptor 3 (FPRL2)HumanYesYesYes
FormylpeptideFPRL1Formylpeptide receptor-like 1 (FPR2/ALX)HumanYesYesYes
Glycoprotein hormone receptorFSHRFollicle stimulating hormone receptor (FSHR)HumanYesYesYes
GABABGABBR1-GABBR2gamma-aminobutyric acid (GABA) B receptor, 1 (GABB1)HumanYes Yes
GalaninGALR1Galanin receptor 1 (GALR1)HumanYesYesYes
GalaninGALR2Galanin receptor 2 (GALR2)HumanYesYesYes
GlucagonGCGRGlucagon receptor (glucagon)HumanYesYesYes
GlucagonGHRHRGrowth hormone releasing hormone receptor (GHRH)HumanYesYesYes
GhrelinGHSRGhrelin receptor (ghrelin)HumanYesYesYes
Class A OrphanGHSR1bGrowth hormone secretagogue receptor 1b (GHSR1b)HumanYesYesYes
GlucagonGIPRGastric inhibitory polypeptide receptor (GIP)HumanYesYesYes
GlucagonGLP1RGlucagon-like peptide receptor 1 (GLP-1)HumanYesYesYes
GlucagonGLP2RGlucagon-like peptide receptor 2 (GLP-2)HumanYesYesYes
Gonadotropin-releasing hormoneGNRHRGonadotropin-releasing hormone receptor (GnRH)HumanYes Yes
Bile acidGPBAR1G protein-coupled bile acid receptor 1 (GPBA)HumanYesYesYes
Class A OrphanGPR1G-protein coupled receptor 1 (GPR1)HumanYesYesYes
Class A OrphanGPR101G-protein coupled receptor 101 (GPR101)HumanYes Yes
Peptide P518GPR103pyroglutamylated RFamide peptide receptor (QRFPR)HumanYes Yes
Other 7TM proteinsGPR107G-protein coupled receptor 107 (GPR107)HumanYesYesYes
Hydroxycarboxylic acidGPR109AHydroxycarboxylic acid receptor 2 (HCA2)HumanYesYesYes
Hydroxycarboxylic acidGPR109BHydroxycarboxylic acid receptor 3 (HCA3)HumanYesYesYes
Class A OrphanGPR119G-protein coupled receptor 119 (GPR119)HumanYes Yes
Class A OrphanGPR12G-protein coupled receptor 12 (GPR12)HumanYesYesYes
Free fatty acidGPR120G-protein coupled receptor 120, long isoform (FFA4)HumanYes Yes
Free fatty acidGPR120SG-protein Coupled Receptor 120, short isoform (FFA4)HumanYesYesYes
Class B OrphanGPR123G-protein coupled receptor 123 (GPR123)HumanYesYesYes
Class A OrphanGPR132G-protein coupled receptor 132 (GPR132)HumanYesYesYes
Class A OrphanGPR135G-protein coupled receptor 135 (GPR135)HumanYesYesYes
Other 7TM proteinsGPR137G-protein coupled receptor 137B (TM7SF1)HumanYesYesYes
Class A OrphanGPR139G-protein coupled receptor 139 (GPR139)HumanYesYesYes
Class A OrphanGPR141G-protein coupled receptor 141 (GPR141)HumanYesYesYes
Class A OrphanGPR142G-protein coupled receptor 142 (GPR142)HumanYesYesYes
Other 7TM proteinsGPR143G-protein coupled receptor 143 (GPR143)HumanYesYesYes
Class A OrphanGPR146G-protein coupled receptor 146 (GPR146)HumanYesYesYes
Class A OrphanGPR148G-protein coupled receptor 148 (GPR148)HumanYesYesYes
Class A OrphanGPR149G-protein coupled receptor 149 (GPR149)HumanYesYesYes
Class A OrphanGPR15G-protein coupled receptor 15 (GPR15)HumanYesYesYes
Class A OrphanGPR150G-protein coupled receptor 150 (GPR150)HumanYesYesYes
Class A OrphanGPR151G-protein coupled receptor 151 (GPR151)HumanYes Yes
Class A OrphanGPR152G-protein coupled receptor 152 (GPR152)HumanYes Yes
Class B OrphanGPR157G-protein coupled receptor 157 (GPR157)HumanYesYesYes
Class A OrphanGPR161G-protein coupled receptor 161 (GPR161)HumanYes Yes
Class A OrphanGPR162G-protein coupled receptor 162 (GPR162)HumanYesYesYes
Class A OrphanGPR17G-protein coupled receptor 17 (GPR17)HumanYes Yes
Class A OrphanGPR171G-protein coupled receptor 171 (GPR171)HumanYesYesYes
Class A OrphanGPR173G-protein coupled receptor 173 (GPR173)HumanYesYesYes
Class A OrphanGPR176G-protein coupled receptor 176 (GPR176)HumanYesYesYes
Class A OrphanGPR18G-protein coupled receptor 18 (GPR18)HumanYesYesYes
Class A OrphanGPR182G-protein coupled receptor 182 (GPR182)HumanYesYesYes
Class A OrphanGPR20G-protein coupled receptor 20 (GPR20)HumanYesYesYes
Class A OrphanGPR22G-protein coupled receptor 22 (GPR22)HumanYes Yes
Class A OrphanGPR23Lysophosphatidic acid receptor 4 (LPA4)HumanYesYesYes
Class A OrphanGPR25G-protein coupled receptor 25 (GPR25)HumanYesYesYes
Class A OrphanGPR26G-protein coupled receptor 26 (GPR26)HumanYesYesYes
Class A OrphanGPR27G-protein coupled receptor 27 (GPR27)HumanYesYesYes
Class A OrphanGPR3G-protein coupled receptor 3 (GPR3)HumanYesYesYes
Estrogen (G protein coupled) receptorGPR30G protein-coupled estrogen receptor 1 (GPER)HumanYesYesYes
Class A OrphanGPR31G-protein coupled receptor 31 (GPR31)HumanYesYesYes
Class A OrphanGPR32G-protein coupled receptor 32 (GPR32)HumanYesYesYes
Class A OrphanGPR35G-protein coupled receptor 35 (GPR35)HumanYesYesYes
Class A OrphanGPR37Endothelin B receptor-like (EDNRBL)HumanYesYesYes
Class A OrphanGPR37L1G protein-coupled receptor 37 like 1 (GPR37L1)HumanYesYesYes
Class A OrphanGPR39G-protein coupled receptor 39 (GPR39)HumanYesYesYes
Class A OrphanGPR4G-protein coupled receptor 4 (GPR4)HumanYesYesYes
Class A OrphanGPR45G-protein coupled receptor 45 (GPR45)HumanYesYesYes
Class A OrphanGPR50G-protein coupled receptor 50 (GPR50)HumanYesYesYes
Class A OrphanGPR52G-protein coupled receptor 52 (GPR52)HumanYesYesYes
Class A OrphanGPR55G protein-coupled receptor 55 (GPR55)HumanYesYesYes
Class A OrphanGPR6G-protein coupled receptor 6 (GPR6)HumanYesYesYes
Class A OrphanGPR61G-protein coupled receptor 61 (GPR61)HumanYesYesYes
Class A OrphanGPR65G-protein coupled receptor 65 (GPR65)HumanYesYesYes
Class A OrphanGPR75G-protein coupled receptor 75 (GPR75)HumanYesYesYes
Class A OrphanGPR78G-protein coupled receptor 78 (GPR78)HumanYesYesYes
Class A OrphanGPR79G protein-coupled receptor 79 pseudogene (GPR79)HumanYesYesYes
Hydroxycarboxylic acidGPR81Hydroxycarboxylic acid receptor 1 (HCA1)HumanYes Yes
Class A OrphanGPR83G-protein coupled receptor 83 (GPR83)HumanYesYesYes
Class A OrphanGPR84G-protein coupled receptor 84 (GPR84)HumanYes Yes
Class A OrphanGPR85G-protein coupled receptor 85 (GPR85)HumanYesYesYes
Class A OrphanGPR88G-protein coupled receptor 88 (GPR88)HumanYesYesYes
Lysophospholipid (LPA)GPR92Lysophosphatidic acid receptor 5 (GPR92)HumanYesYesYes
Class B OrphanGPR97G-protein coupled receptor 97 (GPR97)HumanYesYesYes
Metabotropic glutamateGRM1Metabotropic glutamate receptor 1 (mGlu1)HumanYes Yes
Metabotropic glutamateGRM2Metabotropic glutamate receptor 2 (mGlu2)HumanYesYesYes
Metabotropic glutamateGRM3Metabotropic glutamate receptor 3 (MGlu3)HumanYes Yes
Metabotropic glutamateGRM4Metabotropic glutamate receptor 4 (mGlu4)HumanYesYesYes
Metabotropic glutamateGRM5Metabotropic glutamate receptor 5 (mGlu5)HumanYes Yes
Metabotropic glutamateGRM6Metabotropic glutamate receptor 6 (mGlu6)HumanYesYesYes
BombesinGRPRGastrin releasing peptide receptor (BB2)HumanYesYesYes
OrexinHCRTR1Orexin receptor 1 (OX1)HumanYesYesYes
OrexinHCRTR2Orexin receptor 2 (OX2)HumanYesYesYes
HistamineHRH1Histamine receptor H1 (H1)HumanYesYesYes
HistamineHRH2Histamine receptor H2 (H2)HumanYesYesYes
HistamineHRH3Histamine receptor H3 (H3)HumanYesYesYes
HistamineHRH4Histamine receptor H4 (H4)HumanYesYesYes
5-HydroxytryptamineHTR1A5-hydroxytryptamine receptor 1A (5HT1A)HumanYesYesYes
5-HydroxytryptamineHTR1B5-hydroxytryptamine receptor 1B (5HT1B)HumanYesYesYes
5-HydroxytryptamineHTR1E5-hydroxytryptamine receptor 1E (5HT1E)HumanYes Yes
5-HydroxytryptamineHTR1F5-hydroxytryptamine receptor 1F (5HT1F)HumanYesYesYes
5-HydroxytryptamineHTR2A5-hydroxytryptamine receptor 2A (5HT2A)HumanYesYesYes
5-HydroxytryptamineHTR2B5-hydroxytryptamine receptor 2B (5HT2B)HumanYes Yes
5-HydroxytryptamineHTR2C5-hydroxytryptamine receptor 2C (5HT2C)HumanYesYesYes
5-HydroxytryptamineHTR2C(VGV)5-hydroxytryptamine receptor 2C - VGV isoform (5HT2C)HumanYesYesYes
5-HydroxytryptamineHTR2C(VNV)5-hydroxytryptamine receptor 2C - VNV isoform (5HT2C)HumanYesYesYes
5-HydroxytryptamineHTR2C(VSV)5-hydroxytryptamine receptor 2C - VSV isoform (5HT2C)HumanYesYesYes
5-HydroxytryptamineHTR5A5-hydroxytryptamine receptor 5A (5HT5A)HumanYesYesYes
5-HydroxytryptamineHTR65-hydroxytryptamine receptor 6 (5HT6)HumanYes Yes
5-HydroxytryptamineHTR7A5-hydroxytryptamine receptor 7A (5HT7A)HumanYes  
5-HydroxytryptamineHTR7B5-hydroxytryptamine receptor 7B (5HT7B)HumanYes  
5-HydroxytryptamineHTR7D5-hydroxytryptamine receptor 7D (5HT7D)HumanYesYesYes
Kisspeptin receptorKISS1RKISS1-derived peptide receptor (kisspeptin)HumanYesYesYes
Class A OrphanLGR4Leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4)HumanYesYesYes
Class A OrphanLGR5Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5)HumanYesYesYes
Class A OrphanLGR6Leucine-rich repeat-containing G protein-coupled receptor 6 (LGR6)HumanYesYesYes
Glycoprotein hormone receptorLHCGRChoriogonadotropin receptor (LH)HumanYesYesYes
LeukotrieneLTB4RLeukotriene B4 receptor (BLT1)HumanYesYesYes
VIP and PACAPmADCYAP1R1Adenylate Cyclase Activating Polypeptide 1 Receptor 1 (mPAC1)MouseYesYesYes
AdenosinemADORA2BAdenosine receptor A2B (mA2B)MouseYesYesYes
AdenosinemADORA3adenosine receptor A3 (mA3)MouseYes Yes
AdrenoceptorsmADRA1BAdrenergic receptor alpha 1B (α1B-adrenoreceptor)MouseYes  
ApelinmAGTRL1Apelin receptor (mAPJ)MouseYesYesYes
Vasopressin and OxytocinmAVPR2Vasopressin receptor 2 (V2)MouseYes  
BombesinmBRS3Bombesin receptors 3 (mBB3)MouseYes  
MelanocortinMC1RMelanocortin receptor 1 (MC1)HumanYesYesYes
MelanocortinMC3RMelanocortin receptor 3 (MC3)HumanYesYesYes
MelanocortinMC4RMelanocortin receptor 4 (MC4)HumanYesYesYes
MelanocortinMC4R(T162I)Melanocortin receptor 4 (MC4)HumanYes Yes
Complement peptidemC5AR1Complement component 5a receptor 1 (mC5AR)MouseYesYesYes
MelanocortinMC5RMelanocortin receptor 5 (MC5)HumanYesYesYes
CholecystokininmCCKARCholecystokinin A receptor (mCCK1)MouseYes  
ChemokinemCCR1Chemokine (C-C motif) receptor 1 (mCC1)MouseYes Yes
ChemokinemCCR2Chemokine (C-C motif) receptor 2 (mCCR2)MouseYesYesYes
ChemokinemCCR3Chemokine (C-C motif) receptor 3 (mCCR3)MouseYesYesYes
ChemokinemCCR4Chemokine (C-C motif) receptor 4 (mCCR4)MouseYesYesYes
ChemokinemCCR5Chemokine (C-C motif) receptor 5 (mCCR5)MouseYesYesYes
ChemokinemCCR6Chemokine (C-C motif) receptor 6 (mCCR6)MouseYesYesYes
ChemokinemCCR7Chemokine (C-C motif) receptor 7 (mCCR7)MouseYesYesYes
ChemokinemCCR8Chemokine (C-C motif) receptor 8 (mCCR8)MouseYes Yes
Chemokine mCCR9Chemokine (C-C motif) receptor 9 (mCCR9)MouseYesYesYes
Melanin-concentrating hormone MCHR1Melanin concentrating hormone receptor 1 (MCH1)HumanYesYesYes
Melanin-concentrating hormone MCHR2Melanin-concentrating hormone receptor 2 (MCH2)HumanYesYesYes
ChemokinemCMKLR1Chemokine-Like Receptor 1 (mCMKLR1)MouseYesYesYes
CannabinoidmCNR1Cannabinoid receptor 1 (mCB1)MouseYesYesYes
CannabinoidmCNR2Cannabinoid receptor 2 (mCB2)MouseYesYesYes
Corticotropin-releasing factormCRHR1Corticotropin releasing hormone receptor 1 (mCRF1)MouseYesYesYes
ProstanoidmCRTH2Prostanoid DP2 receptor (mDP2)MouseYes Yes
ChemokinemCX3CR1Chemokine (C-X3-C motif) receptor 1 (mCX3CR1)MouseYesYesYes
ChemokinemCXCR2Chemokine (C-X-C motif) receptor 2 (mCXCR2)MouseYesYesYes
ChemokinemCXCR3Chemokine (C-X-C motif) receptor 3 (mCXCR3)MouseYesYesYes
ChemokinemCXCR4Chemokine (C-X-C motif) receptor 4 (mCXCR4)MouseYesYesYes
ChemokinemCXCR5Burkitt lymphoma receptor (mCXCR5)MouseYesYesYes
ChemokinemCXCR6Chemokine (C-X-C motif) receptor 6 (mCXCR6)MouseYesYesYes
ChemokinemCXCR7Chemokine (C-X-C motif) receptor 7 (mCXCR7)MouseYesYesYes
DopaminemDRD5Dopamine receptor D5 (mDRD5)MouseYes Yes
Class A OrphanmEBI2G-protein coupled receptor 183 (GPR183)MouseYesYesYes
Lysophospholipid (S1P)mEDG1Sphingosine 1-phosphate receptor 1 (mS1P1)MouseYesYesYes
Lysophospholipid (S1P)mEDG3Sphingosine 1-phosphate receptor 3 (S1P3)MouseYesYesYes
Lysophospholipid (S1P)mEDG5Sphingosine 1-phosphate receptor 2 (mS1P2)MouseYes Yes
EndothelinmEDNRAEndothelin receptor type A (mETA)MouseYesYesYes
EndothelinmEDNRBEndothelin receptor type B (mETB)MouseYesYesYes
Protease activatedmF2RL1Thrombin receptor-like 1 (PAR2) (PAR2)Mouse Yes 
Free Fatty AcidmFFAR1Free fatty acid receptor 1 (FFA1)MouseYes Yes
Formylpeptide mFPR1Formylpeptide receptor 1 (mFPR1)MouseYes Yes
FormylpeptidemFPR2Formylpeptide receptor 2 (FPR2)MouseYesYesYes
GalaninmGALR1Galanin receptor 1 (mGALR1)MouseYes  
GalaninmGALR2Galanin Receptor 2 (mGALR2)MouseYesYesYes
GlucagonmGCGRGlucagon Receptor (glucagon)MouseYesYesYes
GhrelinmGHSRGhrelin receptor (ghrelin)MouseYesYesYes
GlucagonmGIPRGastric inhibitory polypeptide receptor (mGIP)MouseYesYesYes
GlucagonmGLP1RGlucagon-like peptide receptor 1 (mGLP-1)MouseYesYesYes
GlucagonmGLP1R-ADCY2Glucagon-like peptide receptor 1 (mGLP-1)Mouse Yes 
Class A OrphanmGPR1G-Protein Coupled Receptor 1 (mGPR1)MouseYes Yes
Free fatty acidmGPR120G protein-coupled receptor 120 (mGPR120)MouseYesYesYes
Class A OrphanmGPR84G-protein coupled receptor 84, Mouse (GPR84)MouseYes Yes
OrexinmHCRTR1Orexin receptor 1 (mOX1)MouseYes  
5-HydroxytryptaminemHTR2A5-Hydroxytryptamine receptor 2A (m5HT2A)MouseYes Yes
5-HydroxytryptaminemHTR2C5-Hydroxytryptamine receptor 2C (m5HT2C)MouseYes Yes
MotilinMLNRMotilin receptor (motilin)HumanYesYesYes
LeukotrienemLTB4RLeukotriene B4 receptor (mBLT1)MouseYes Yes
Melanocortin mMC3RMelanocortin receptor 3 (mMC3)MouseYes  
Melanocortin mMC4RMelanocortin receptor 4 (mMC4)MouseYes  
Melanocortin mMC5RMelanocortin receptor 5 (MC5)MouseYes  
Melanin-concentrating hormonemMCHR1Melanin concentrating hormone receptor 1 (MCH1)MouseYes Yes
Neuropeptide YmNPY1RNeuropeptide Y1 receptor (Y1)MouseYes Yes
Neuropeptide YmNPY2RNeuropeptide Y2 receptor (NPY2R)MouseYes Yes
OpioidmOPRD1Opioid receptor delta (δ (murine))MouseYesYesYes
OpioidmOPRK1Opioid receptor kappa (κ (murine))MouseYesYesYes
OpioidmOPRM1Opioid receptor mu (μ (murine))MouseYesYesYes
Vasopressin and OxytocinmOXTROxytocin recepter (OT)MouseYes Yes
P2YmP2RY12P2Y Purinoceptor 12 (mP2Y12)MouseYesYesYes
P2YmP2RY6P2Y Purinoceptor 6 (P2Y6)MouseYes Yes
Neuropeptide YmPPYR1Pancreatic polypeptide receptor 1 (Y4)MouseYes Yes
Platelet-activating factor mPTAFRPlatelet-activating factor receptor (mPAF)MouseYesYesYes
ProstanoidmPTGER4Prostaglandin E receptor 4 (subtype EP4) (EP4)MouseYesYesYes
ProstanoidmPTGIRProstanoid IP1 receptor (IP1)MouseYes  
Class A OrphanMRGPRDMAS-related GPR, member D (MRGPRD)HumanYesYesYes
Class A OrphanMRGPREMAS-related GPR, member E (MRGPRE)HumanYesYesYes
Class A OrphanMRGPRFMAS-related GPR, member F (MRGPRF)HumanYesYesYes
Class A OrphanMRGPRX1MAS-related GPR, member X1 (MRGPRX1)HumanYes Yes
Class A OrphanMRGPRX2MAS-related GPR, member X2 (MRGX2)HumanYesYesYes
Class A OrphanMRGPRX4MAS-related GPR, member X4 (MRGPRX4)HumanYesYesYes
RhodopsinmRHO(P23H)Rhodopsin (Rhodopsin)MouseYes Yes
RelaxinmRXFP1Relaxin family peptide receptor 1 (RXFP1)MouseYes Yes
RelaxinmRXFP3Relaxin family peptide receptor 3 (RXFP3)MouseYesYesYes
RelaxinmRXFP4Relaxin family peptide receptor 4 (RXFP4)MouseYesYesYes
SomatostatinmSSTR2Somatostatin receptor 2 (mSST2)MouseYesYesYes
SomatostatinmSSTR5Somatostatin receptor 5 (mSRIF1B)MouseYes Yes
Trace aminemTAAR1Trace amine associated receptor 1 (mouse) (mTA1)MouseYes Yes
Tachykinin mTACR1Tachykinin receptor 1 (mNK1)MouseYes  
MelatoninMTNR1AMelatonin receptor 1A (MT1)HumanYesYesYes
MelatoninMTNR1BMelatonin receptor 1B (MT2)HumanYesYesYes
UrotensinmUTR2Urotensin II receptor (mUT)MouseYesYesYes
VIP and PACAPmVIPR1Vasoactive intestinal peptide receptor 1 (mVPAC1)MouseYesYesYes
BombesinNMBRNeuromedin B Receptor (BB1)HumanYesYesYes
Neuromedin UNMU1RNeuromedin U receptor 1 (NMU1)HumanYesYesYes
Neuropeptide B & WNPBWR1Neuropeptides B/W receptor 1 (NPBW1)HumanYesYesYes
Neuropeptide B & WNPBWR2Neuropeptides B/W receptor 2 (NPBW2)HumanYesYesYes
Neuropeptide FF & AFNPFFR1Neuropeptide FF receptor 1 (NPFF1)HumanYesYesYes
Neuropeptide SNPSR1bneuropeptide S receptor 1 (NPS receptor)HumanYesYesYes
Neuropeptide YNPY1RNeuropeptide Y receptor Y1 (Y1)HumanYesYesYes
Neuropeptide YNPY2RNeuropeptide Y receptor Y2 (Y2)HumanYesYesYes
NeurotensinNTSR1Neurotensin receptor 1 (NTS1)HumanYesYesYes
Class A OrphanOPN5Opsin 5 (OPN5)HumanYesYesYes
OpioidOPRD1Opioid receptor delta (δ)HumanYesYesYes
OpioidOPRK1Opioid receptor kappa (κ)HumanYesYesYes
OpioidOPRL1Opioid receptor-like receptor (NOP)HumanYesYesYes
OpioidOPRM1Opioid receptor mu (μ)HumanYesYesYes
LeukotrieneOXER1Oxoeicosanoid (OXE) receptor 1 (OXE)HumanYesYesYes
Class A OrphanOXGR1Oxoglutarate (alpha-ketoglutarate) receptor 1 (OXGR1)HumanYesYesYes
Vasopressin and OxytocinOXTROxytocin recepter (OT)HumanYesYesYes
P2YP2RY1Purinergic receptor P2Y, G-protein coupled, 1 (P2RY1)HumanYesYesYes
P2YP2RY11Purinergic receptor P2Y, G-protein coupled, 11 (P2Y11)HumanYesYesYes
P2YP2RY12Purinergic receptor P2Y, G-protein coupled, 12 (P2Y12)HumanYesYesYes
P2YP2RY2Purinergic receptor P2Y, G-protein coupled, 2 (P2Y2)HumanYesYesYes
P2YP2RY4Pyrimidinergic receptor P2Y, G-protein coupled, 4 (P2Y4)HumanYesYesYes
P2YP2RY6Pyrimidinergic receptor P2Y, G-protein coupled, 6 (P2Y6)HumanYesYesYes
Class A OrphanP2RY8Purinergic receptor P2Y, G-protein coupled, 8 (P2RY8)HumanYesYesYes
Neuropeptide YPPYR1Pancreatic polypeptide receptor 1 (Y4)HumanYesYesYes
Prolactin releasing peptide receptorPRLHRProlactin releasing hormone receptor (PRRP)HumanYesYesYes
ProkineticinPROKR1Prokineticin receptor 1 (PKR1)HumanYesYesYes
ProkineticinPROKR2Prokineticin receptor 2 (PKR2)HumanYesYesYes
Platelet-activating factorPTAFRPlatelet activating receptor (PAF)HumanYesYesYes
ProstanoidPTGDRProstaglandin D2 receptor (DP1)HumanYesYesYes
ProstanoidPTGER1Prostaglandin E receptor 1 (subtype EP1) (EP1)HumanYes Yes
ProstanoidPTGER2Prostaglandin E receptor 2 (subtype EP2) (EP2)HumanYesYesYes
ProstanoidPTGER3Prostaglandin E receptor 3 (subtype EP3) (EP3)HumanYesYesYes
ProstanoidPTGER4Prostaglandin E receptor 4 (subtype EP4) (EP4)HumanYesYesYes
ProstanoidPTGFRProstaglandin F receptor (FP) (FP)HumanYesYesYes
ProstanoidPTGIRProstaglandin I2 (prostacyclin) receptor (IP) (IP1)HumanYesYesYes
Parathyroid hormonePTHR1Parathyroid hormone receptor 1 (PTH1)HumanYesYesYes
Parathyroid hormonePTHR2Parathyroid hormone receptor 2 (PTH2)HumanYesYesYes
AcetylcholinerCHRM4Cholinergic receptor, muscarinic 4 (rM4)RatYesYesYes
CannabinoidrCNR2Cannabinoid receptor 2 (CB2)RatYes Yes
ProstanoidrCRTH2Prostanoid DP2 receptor (rGPR44)RatYesYesYes
DopaminerDRD1Dopamine receptor D1 (rD1)RatYesYesYes
DopaminerDRD2LDopamine Receptor D2 (long isoform) (rD2L)RatYesYesYes
DopaminerDRD2SDopamine Receptor D2 (short isoform) (rD2S)RatYes Yes
Lysophospholipid (S1P)rEDG5Sphingosine 1-phosphate receptor 2 (rS1P2)RatYes Yes
Free Fatty AcidrFFAR1Free fatty acid receptor 1 (FFA1)RatYesYesYes
Free fatty acidrGPR120G-protein coupled receptor 120 (FFA4)RatYesYesYes
Class A OrphanrGPR35G-protein coupled receptor 35 (rGPR35)RatYesYesYes
5-HydroxytryptaminerHTR2C5-hydroxytryptamine receptor 2C (HTR2C)RatYesYesYes
OpioidrOPRM1Opioid receptor mu (μ)RatYesYesYes
ProkineticinrPROKR1Prokineticin receptor 1 (rPROKR1)RatYesYesYes
ProkineticinrPROKR2Prokineticin receptor 2 (rPKR2)RatYesYesYes
ProstanoidrPTGER4Prostaglandin E receptor 4 (subtype EP4), rat (rEP4)RatYes Yes
Trace aminerTAAR1Trace amine associated receptor 1 (rat) (rTAR1)RatYes Yes
VIP and PACAPrVIPR1Vasoactive intestinal peptide receptor 1 (rVPAC1)RatYesYesYes
RelaxinRXFP1Relaxin family peptide receptor 1 (RXFP1)HumanYesYesYes
RelaxinRXFP2Relaxin family peptide receptor 2 (RXFP2)HumanYes Yes
RelaxinRXFP3Relaxin family peptide receptor 3 (RXFP3)HumanYesYesYes
RelaxinRXFP4Relaxin family peptide receptor 4 (RXFP4)HumanYesYesYes
GlucagonSCTRSecretin receptor (secretin)HumanYesYesYes
Lysophospholipid (S1P)sEDG5Sphingosine 1-phosphate receptor 2 (sS1P2)SimianYes Yes
FrizzledSMO(W535L)Smoothened, Frizzled class receptor (Smoothened)HumanYes Yes
SomatostatinSSTR1Somatostatin receptor 1 (SST1)HumanYesYesYes
SomatostatinSSTR2Somatostatin receptor 2 (SST2)HumanYesYesYes
SomatostatinSSTR3Somatostatin receptor 3 (SST3)HumanYesYesYes
SomatostatinSSTR4Somatostatin receptor 4 (SST4)HumanYesYesYes
SomatostatinSSTR5Somatostatin receptor 5 (SST5)HumanYesYesYes
Trace amineTAAR1trace amine associated receptor 1 (TA1)HumanYes Yes
Class A OrphanTAAR5Trace amine associated receptor 5 (TAAR5)HumanYesYesYes
TachykininTACR1Tachykinin receptor 1 (NK1)HumanYesYesYes
TachykininTACR2Tachykinin receptor 2 (NK2)HumanYesYesYes
TachykininTACR3Tachykinin receptor 3 (NK3)HumanYesYesYes
ProstanoidTBXA2RThromboxane A2 receptor (TP)HumanYesYesYes
Thyrotropin releasing hormoneTRHRThyrotropin-releasing hormone receptor (TRH1)HumanYesYesYes
Glycoprotein hormone receptorTSHR(L)Thyroid Stimulating Hormone Receptor (TSH)HumanYes Yes
UrotensinUTR2Urotensin II receptor (UT)HumanYesYesYes
VIP and PACAPVIPR1Vasoactive intestinal peptide receptor 1 (VPAC1)HumanYesYesYes
VIP and PACAPVIPR2Vasoactive intestinal peptide receptor 2 (VPAC2)HumanYesYesYes
ChemokineXCR1Chemokine (C motif) XC receptor 1 (XCR1)HumanYes Yes
+

Known GPCR Target List

View our complete list of Known GPCR Targets
FamilyGene Symbol ▲Common NameSpeciesCell LinesAssay Ready KitsService
VIP and PACAPADCYAP1R1Adenylate cyclase activating polypeptide receptor 1 (PAC1)HumanYesYesYes
AdenosineADORA1Adenosine receptor A1 (A1)HumanYes Yes
AdenosineADORA2AAdenosine receptor A2A (A2A)HumanYes Yes
AdenosineADORA2BAdenosine receptor A2B (A2B)HumanYesYesYes
AdenosineADORA3Adenosine receptor A3 (A3)HumanYesYesYes
AdrenoceptorsADRA1AAdrenergic receptor alpha 1A (α1A-adrenoceptor)HumanYes Yes
AdrenoceptorsADRA1BAdrenergic receptor alpha 1B (α1B-adrenoceptor)HumanYesYesYes
AdrenoceptorsADRA1D(82-572)Adrenergic receptor alpha 1D (α1D-adrenoceptor)HumanYes Yes
AdrenoceptorsADRA2AAdrenergic receptor alpha 2A (α2A-adrenoceptor)HumanYesYesYes
AdrenoceptorsADRA2BAdrenergic receptor alpha 2B (α2B-adrenoceptor)HumanYesYesYes
AdrenoceptorsADRA2CAdrenergic receptor alpha 2C (α2C-adrenoceptor)HumanYesYesYes
AdrenoceptorsADRB1Adrenergic receptor beta 1 (β1-adrenoreceptor)HumanYesYesYes
AdrenoceptorsADRB2Adrenergic receptor beta 2 (β2-adrenoreceptor)HumanYesYesYes
AdrenoceptorsADRB2(W158A)Adrenergic receptor beta 2 (β2-adrenoreceptor)HumanYesYesYes
AdrenoceptorsADRB3Adrenergic receptor beta 3 (β3-adrenoreceptor)HumanYesYesYes
AngiotensinAGTR1Angiotensin II receptor, type 1 (AT1)HumanYesYesYes
ApelinAGTRL1Apelin receptor (APJ)HumanYesYesYes
Vasopressin and OxytocinAVPR1AVasopressin receptor 1A (V1A)HumanYesYesYes
Vasopressin and OxytocinAVPR1BVasopressin receptor 1B (V1B)HumanYesYesYes
Vasopressin and OxytocinAVPR2Vasopressin receptor 2 (V2)HumanYesYesYes
Vasopressin and OxytocinAVPR2(S167T)Vasopressin receptor 2 (V2)HumanYes Yes
BradykininBDKRB1Bradykinin receptor B1 (B1)HumanYesYesYes
BradykininBDKRB2Bradykinin receptor B2 (B2)HumanYesYesYes
BombesinBRS3Bombesin receptor, subtype 3 (BB3)HumanYesYesYes
Complement peptideC3AR1Complement component 3a receptor 1 (C3A)HumanYesYesYes
Complement peptideC5AR1Complement component 5a receptor 1 (C5A)HumanYesYesYes
Complement peptideC5L2G-Protein Coupled Receptor 77 (C5L2)HumanYesYesYes
CalcitoninCALCRCalcitonin receptor (CT)HumanYesYesYes
CalcitoninCALCRL-RAMP1Calcitonin receptor-like (Calcitonin receptor-like receptor)HumanYesYesYes
CalcitoninCALCRL-RAMP2Calcitonin receptor-like (Calcitonin receptor-like receptor)HumanYesYesYes
CalcitoninCALCRL-RAMP3Calcitonin receptor-like (Calcitonin receptor-like receptor)HumanYesYesYes
CalcitoninCALCR-RAMP2Calcitonin receptor (CT)HumanYesYesYes
CalcitoninCALCR-RAMP3Calcitonin receptor (CT)HumanYesYesYes
Calcium sensingCASRCalcium-sensing receptor (CaS)HumanYes Yes
CholecystokininCCKARCholecystokinin A receptor (CCK1)HumanYesYesYes
CholecystokininCCKBRCholecystokinin B receptor (CCK2)HumanYesYesYes
ChemokineCCR1Chemokine (C-C motif) receptor 1 (CCR1)HumanYesYesYes
ChemokineCCR10Chemokine (C-C motif) receptor 10 (CCR10)HumanYesYesYes
ChemokineCCR2Chemokine (C-C motif) receptor 2 (CCR2)HumanYesYesYes
ChemokineCCR3Chemokine (C-C motif) receptor 3 (CCR3)HumanYesYesYes
ChemokineCCR4Chemokine (C-C motif) receptor 4 (CCR4)HumanYesYesYes
ChemokineCCR5Chemokine (C-C motif) receptor 5 (CCR5)HumanYesYesYes
ChemokineCCR6Chemokine (C-C motif) receptor 6 (CCR6)HumanYesYesYes
ChemokineCCR7Chemokine (C-C motif) receptor 7 (CCR7)HumanYesYesYes
ChemokineCCR8Chemokine (C-C motif) receptor 8 (CCR8)HumanYesYesYes
ChemokineCCR9Chemokine (C-C motif) receptor 9 (CCR9)HumanYesYesYes
ChemokineCCRL1chemokine (C-C motif) receptor-like 1 (CCRL1)HumanYes Yes
ChemokineCCRL2Chemokine (C-C motif) receptor-like 2 (CCRL2)HumanYesYesYes
Lysophospholipid (S1P)cEDG5Sphingosine 1-phosphate receptor 2 (cS1P2)CanineYes Yes
AcetylcholineCHRM1Cholinergic receptor, muscarinic 1 (M1)HumanYesYesYes
AcetylcholineCHRM2Cholinergic receptor, muscarinic 2 (M2)HumanYesYesYes
AcetylcholineCHRM3Cholinergic receptor, muscarinic 3 (M3)HumanYesYesYes
AcetylcholineCHRM4Cholinergic receptor, muscarinic 4 (M4)HumanYesYesYes
AcetylcholineCHRM5Cholinergic receptor, muscarinic 5 (M5)HumanYesYesYes
ChemerinCMKLR1Chemokine-like receptor 1 (CMKLR1)HumanYesYesYes
CannabinoidCNR1Cannabinoid receptor 1 (CB1)HumanYesYesYes
CannabinoidCNR2Cannabinoid receptor 2 (CB2)HumanYesYesYes
Corticotropin-releasing factorCRHR1Corticotropin releasing hormone receptor 1 (CRF1)HumanYesYesYes
Corticotropin-releasing factorCRHR2Corticotropin releasing hormone receptor 2 (CRF2)HumanYesYesYes
ProstanoidCRTH2prostaglandin D2 receptor 2 (PTGDR2)HumanYesYesYes
ChemokineCX3CR1Chemokine C-X3-C receptor 1 (CX3CR1)HumanYesYesYes
ChemokineCXCR1Chemokine (C-X-C motif) receptor 1 (CXCR1)HumanYesYesYes
ChemokineCXCR2Chemokine (C-X-C motif) receptor 2 (CXCR2)HumanYesYesYes
ChemokineCXCR3Chemokine (C-X-C motif) receptor 3 (CXCR3)HumanYesYesYes
ChemokineCXCR4Chemokine (C-X-C motif) receptor 4 (CXCR4)HumanYesYesYes
ChemokineCXCR5Burkitt lymphoma receptor (CXCR5)HumanYesYesYes
ChemokineCXCR6Chemokine (C-X-C motif) receptor 6 (CXCR6)HumanYesYesYes
ChemokineCXCR7Chemokine (C-X-C motif) receptor 7 (CXCR7)HumanYesYesYes
Chemokinecyno CXCR1Chemokine (C-X-C motif) receptor 1 (CXCR1)Macaca fascicularisYesYesYes
Chemokinecyno CXCR2Chemokine (C-X-C motif) receptor 2 (CXCR2)Macaca fascicularisYesYesYes
Free fatty acidcyno GPR120G-protein coupled receptor 120 (FFA4)Macaca fascicularisYes Yes
Leukotriene CYSLTR2Cysteinyl leukotriene receptor 2 (CYSLT2)HumanYes Yes
ChemokineDARCDuffy blood group, chemokine receptor (FY)HumanYesYesYes
DopamineDRD1Dopamine receptor D1 (D1)HumanYesYesYes
DopamineDRD2LDopamine Receptor D2 (long isoform) (D2L)HumanYesYesYes
DopamineDRD2SDopamine Receptor D2 (short isoform) (D2S)HumanYesYesYes
DopamineDRD3Dopamine Receptor D3 (D3)HumanYesYesYes
DopamineDRD4Dopamine Receptor D4 (D4)HumanYesYesYes
DopamineDRD5Dopamine receptor D5 (D5)HumanYesYesYes
Lysophospholipid (S1P)EDG1Sphingosine 1-phosphate receptor 1 (S1P1)HumanYesYesYes
Lysophospholipid (LPA)EDG2Lysophosphatidic acid receptor 1 (LPA1)HumanYes Yes
Lysophospholipid (S1P)EDG3Sphingosine 1-phosphate receptor 3 (S1P3)HumanYesYesYes
Lysophospholipid (LPA)EDG4Lysophosphatidic acid receptor 2 (LPA2)HumanYesYesYes
Lysophospholipid (S1P)EDG5Sphingosine 1-phosphate receptor 2 (S1P2)HumanYesYesYes
Lysophospholipid (S1P)EDG6Sphingosine 1-phosphate receptor 4 (S1P4)HumanYes Yes
Lysophospholipid (LPA)EDG7Lysophosphatidic acid receptor 3 (LPA3)HumanYesYesYes
EndothelinEDNRAEndothelin receptor type A (ETA)HumanYesYesYes
EndothelinEDNRBEndothelin receptor type B (ETB)HumanYesYesYes
Protease activatedF2RCoagulation factor II (thrombin) receptor (PAR1)HumanYesYesYes
Protease activatedF2RL1Coagulation factor II (thrombin) receptor-like 1 (PAR2) (PAR2)HumanYesYesYes
Protease activatedF2RL3Coagulation factor II (thrombin) receptor-like 3 (PAR4) (PAR4)HumanYesYesYes
Free Fatty AcidFFAR1Free fatty acid receptor 1 (FFA1)HumanYes Yes
Free Fatty AcidFFAR2Free fatty acid receptor 2 (GPR43)HumanYes Yes
Free Fatty AcidFFAR3Free fatty acid receptor 3 (GPR41)HumanYesYesYes
FormylpeptideFPR1Formylpeptide receptor 1 (FPR1)HumanYesYesYes
FormylpeptideFPR3Formyl peptide receptor 3 (FPRL2)HumanYesYesYes
FormylpeptideFPRL1Formylpeptide receptor-like 1 (FPR2/ALX)HumanYesYesYes
Glycoprotein hormone receptorFSHRFollicle stimulating hormone receptor (FSHR)HumanYesYesYes
GABABGABBR1-GABBR2gamma-aminobutyric acid (GABA) B receptor, 1 (GABB1)HumanYes Yes
GalaninGALR1Galanin receptor 1 (GALR1)HumanYesYesYes
GalaninGALR2Galanin receptor 2 (GALR2)HumanYesYesYes
GlucagonGCGRGlucagon receptor (glucagon)HumanYesYesYes
GlucagonGHRHRGrowth hormone releasing hormone receptor (GHRH)HumanYesYesYes
GhrelinGHSRGhrelin receptor (ghrelin)HumanYesYesYes
GlucagonGIPRGastric inhibitory polypeptide receptor (GIP)HumanYesYesYes
GlucagonGLP1RGlucagon-like peptide receptor 1 (GLP-1)HumanYesYesYes
GlucagonGLP2RGlucagon-like peptide receptor 2 (GLP-2)HumanYesYesYes
Gonadotropin-releasing hormoneGNRHRGonadotropin-releasing hormone receptor (GnRH)HumanYes Yes
Bile acidGPBAR1G protein-coupled bile acid receptor 1 (GPBA)HumanYesYesYes
Peptide P518GPR103pyroglutamylated RFamide peptide receptor (QRFPR)HumanYes Yes
Other 7TM proteinsGPR107G-protein coupled receptor 107 (GPR107)HumanYesYesYes
Hydroxycarboxylic acidGPR109AHydroxycarboxylic acid receptor 2 (HCA2)HumanYesYesYes
Hydroxycarboxylic acidGPR109BHydroxycarboxylic acid receptor 3 (HCA3)HumanYesYesYes
Free fatty acidGPR120G-protein coupled receptor 120, long isoform (FFA4)HumanYes Yes
Free fatty acidGPR120SG-protein Coupled Receptor 120, short isoform (FFA4)HumanYesYesYes
Other 7TM proteinsGPR137G-protein coupled receptor 137B (TM7SF1)HumanYesYesYes
Other 7TM proteinsGPR143G-protein coupled receptor 143 (GPR143)HumanYesYesYes
Estrogen (G protein coupled) receptorGPR30G protein-coupled estrogen receptor 1 (GPER)HumanYesYesYes
Hydroxycarboxylic acidGPR81Hydroxycarboxylic acid receptor 1 (HCA1)HumanYes Yes
Lysophospholipid (LPA)GPR92Lysophosphatidic acid receptor 5 (GPR92)HumanYesYesYes
Metabotropic glutamateGRM1Metabotropic glutamate receptor 1 (mGlu1)HumanYes Yes
Metabotropic glutamateGRM2Metabotropic glutamate receptor 2 (mGlu2)HumanYesYesYes
Metabotropic glutamateGRM3Metabotropic glutamate receptor 3 (MGlu3)HumanYes Yes
Metabotropic glutamateGRM4Metabotropic glutamate receptor 4 (mGlu4)HumanYesYesYes
Metabotropic glutamateGRM5Metabotropic glutamate receptor 5 (mGlu5)HumanYes Yes
Metabotropic glutamateGRM6Metabotropic glutamate receptor 6 (mGlu6)HumanYesYesYes
BombesinGRPRGastrin releasing peptide receptor (BB2)HumanYesYesYes
OrexinHCRTR1Orexin receptor 1 (OX1)HumanYesYesYes
OrexinHCRTR2Orexin receptor 2 (OX2)HumanYesYesYes
HistamineHRH1Histamine receptor H1 (H1)HumanYesYesYes
HistamineHRH2Histamine receptor H2 (H2)HumanYesYesYes
HistamineHRH3Histamine receptor H3 (H3)HumanYesYesYes
HistamineHRH4Histamine receptor H4 (H4)HumanYesYesYes
5-HydroxytryptamineHTR1A5-hydroxytryptamine receptor 1A (5HT1A)HumanYesYesYes
5-HydroxytryptamineHTR1B5-hydroxytryptamine receptor 1B (5HT1B)HumanYesYesYes
5-HydroxytryptamineHTR1E5-hydroxytryptamine receptor 1E (5HT1E)HumanYes Yes
5-HydroxytryptamineHTR1F5-hydroxytryptamine receptor 1F (5HT1F)HumanYesYesYes
5-HydroxytryptamineHTR2A5-hydroxytryptamine receptor 2A (5HT2A)HumanYesYesYes
5-HydroxytryptamineHTR2B5-hydroxytryptamine receptor 2B (5HT2B)HumanYes Yes
5-HydroxytryptamineHTR2C5-hydroxytryptamine receptor 2C (5HT2C)HumanYesYesYes
5-HydroxytryptamineHTR2C(VGV)5-hydroxytryptamine receptor 2C - VGV isoform (5HT2C)HumanYesYesYes
5-HydroxytryptamineHTR2C(VNV)5-hydroxytryptamine receptor 2C - VNV isoform (5HT2C)HumanYesYesYes
5-HydroxytryptamineHTR2C(VSV)5-hydroxytryptamine receptor 2C - VSV isoform (5HT2C)HumanYesYesYes
5-HydroxytryptamineHTR5A5-hydroxytryptamine receptor 5A (5HT5A)HumanYesYesYes
5-HydroxytryptamineHTR65-hydroxytryptamine receptor 6 (5HT6)HumanYes Yes
5-HydroxytryptamineHTR7A5-hydroxytryptamine receptor 7A (5HT7A)HumanYes  
5-HydroxytryptamineHTR7B5-hydroxytryptamine receptor 7B (5HT7B)HumanYes  
5-HydroxytryptamineHTR7D5-hydroxytryptamine receptor 7D (5HT7D)HumanYesYesYes
Kisspeptin receptorKISS1RKISS1-derived peptide receptor (kisspeptin)HumanYesYesYes
Glycoprotein hormone receptorLHCGRChoriogonadotropin receptor (LH)HumanYesYesYes
LeukotrieneLTB4RLeukotriene B4 receptor (BLT1)HumanYesYesYes
VIP and PACAPmADCYAP1R1Adenylate Cyclase Activating Polypeptide 1 Receptor 1 (mPAC1)MouseYesYesYes
AdenosinemADORA2BAdenosine receptor A2B (mA2B)MouseYesYesYes
AdenosinemADORA3adenosine receptor A3 (mA3)MouseYes Yes
AdrenoceptorsmADRA1BAdrenergic receptor alpha 1B (α1B-adrenoreceptor)MouseYes  
ApelinmAGTRL1Apelin receptor (mAPJ)MouseYesYesYes
Vasopressin and OxytocinmAVPR2Vasopressin receptor 2 (V2)MouseYes  
BombesinmBRS3Bombesin receptors 3 (mBB3)MouseYes  
MelanocortinMC1RMelanocortin receptor 1 (MC1)HumanYesYesYes
MelanocortinMC3RMelanocortin receptor 3 (MC3)HumanYesYesYes
MelanocortinMC4RMelanocortin receptor 4 (MC4)HumanYesYesYes
MelanocortinMC4R(T162I)Melanocortin receptor 4 (MC4)HumanYes Yes
Complement peptidemC5AR1Complement component 5a receptor 1 (mC5AR)MouseYesYesYes
MelanocortinMC5RMelanocortin receptor 5 (MC5)HumanYesYesYes
CholecystokininmCCKARCholecystokinin A receptor (mCCK1)MouseYes  
ChemokinemCCR1Chemokine (C-C motif) receptor 1 (mCC1)MouseYes Yes
ChemokinemCCR2Chemokine (C-C motif) receptor 2 (mCCR2)MouseYesYesYes
ChemokinemCCR3Chemokine (C-C motif) receptor 3 (mCCR3)MouseYesYesYes
ChemokinemCCR4Chemokine (C-C motif) receptor 4 (mCCR4)MouseYesYesYes
ChemokinemCCR5Chemokine (C-C motif) receptor 5 (mCCR5)MouseYesYesYes
ChemokinemCCR6Chemokine (C-C motif) receptor 6 (mCCR6)MouseYesYesYes
ChemokinemCCR7Chemokine (C-C motif) receptor 7 (mCCR7)MouseYesYesYes
ChemokinemCCR8Chemokine (C-C motif) receptor 8 (mCCR8)MouseYes Yes
Chemokine mCCR9Chemokine (C-C motif) receptor 9 (mCCR9)MouseYesYesYes
Melanin-concentrating hormone MCHR1Melanin concentrating hormone receptor 1 (MCH1)HumanYesYesYes
Melanin-concentrating hormone MCHR2Melanin-concentrating hormone receptor 2 (MCH2)HumanYesYesYes
ChemokinemCMKLR1Chemokine-Like Receptor 1 (mCMKLR1)MouseYesYesYes
CannabinoidmCNR1Cannabinoid receptor 1 (mCB1)MouseYesYesYes
CannabinoidmCNR2Cannabinoid receptor 2 (mCB2)MouseYesYesYes
Corticotropin-releasing factormCRHR1Corticotropin releasing hormone receptor 1 (mCRF1)MouseYesYesYes
ProstanoidmCRTH2Prostanoid DP2 receptor (mDP2)MouseYes Yes
ChemokinemCX3CR1Chemokine (C-X3-C motif) receptor 1 (mCX3CR1)MouseYesYesYes
ChemokinemCXCR2Chemokine (C-X-C motif) receptor 2 (mCXCR2)MouseYesYesYes
ChemokinemCXCR3Chemokine (C-X-C motif) receptor 3 (mCXCR3)MouseYesYesYes
ChemokinemCXCR4Chemokine (C-X-C motif) receptor 4 (mCXCR4)MouseYesYesYes
ChemokinemCXCR5Burkitt lymphoma receptor (mCXCR5)MouseYesYesYes
ChemokinemCXCR6Chemokine (C-X-C motif) receptor 6 (mCXCR6)MouseYesYesYes
ChemokinemCXCR7Chemokine (C-X-C motif) receptor 7 (mCXCR7)MouseYesYesYes
DopaminemDRD5Dopamine receptor D5 (mDRD5)MouseYes Yes
Lysophospholipid (S1P)mEDG1Sphingosine 1-phosphate receptor 1 (mS1P1)MouseYesYesYes
Lysophospholipid (S1P)mEDG3Sphingosine 1-phosphate receptor 3 (S1P3)MouseYesYesYes
Lysophospholipid (S1P)mEDG5Sphingosine 1-phosphate receptor 2 (mS1P2)MouseYes Yes
EndothelinmEDNRAEndothelin receptor type A (mETA)MouseYesYesYes
EndothelinmEDNRBEndothelin receptor type B (mETB)MouseYesYesYes
Protease activatedmF2RL1Thrombin receptor-like 1 (PAR2) (PAR2)Mouse Yes 
Free Fatty AcidmFFAR1Free fatty acid receptor 1 (FFA1)MouseYes Yes
Formylpeptide mFPR1Formylpeptide receptor 1 (mFPR1)MouseYes Yes
FormylpeptidemFPR2Formylpeptide receptor 2 (FPR2)MouseYesYesYes
GalaninmGALR1Galanin receptor 1 (mGALR1)MouseYes  
GalaninmGALR2Galanin Receptor 2 (mGALR2)MouseYesYesYes
GlucagonmGCGRGlucagon Receptor (glucagon)MouseYesYesYes
GhrelinmGHSRGhrelin receptor (ghrelin)MouseYesYesYes
GlucagonmGIPRGastric inhibitory polypeptide receptor (mGIP)MouseYesYesYes
GlucagonmGLP1RGlucagon-like peptide receptor 1 (mGLP-1)MouseYesYesYes
GlucagonmGLP1R-ADCY2Glucagon-like peptide receptor 1 (mGLP-1)Mouse Yes 
Free fatty acidmGPR120G protein-coupled receptor 120 (mGPR120)MouseYesYesYes
OrexinmHCRTR1Orexin receptor 1 (mOX1)MouseYes  
5-HydroxytryptaminemHTR2A5-Hydroxytryptamine receptor 2A (m5HT2A)MouseYes Yes
5-HydroxytryptaminemHTR2C5-Hydroxytryptamine receptor 2C (m5HT2C)MouseYes Yes
MotilinMLNRMotilin receptor (motilin)HumanYesYesYes
LeukotrienemLTB4RLeukotriene B4 receptor (mBLT1)MouseYes Yes
Melanocortin mMC3RMelanocortin receptor 3 (mMC3)MouseYes  
Melanocortin mMC4RMelanocortin receptor 4 (mMC4)MouseYes  
Melanocortin mMC5RMelanocortin receptor 5 (MC5)MouseYes  
Melanin-concentrating hormonemMCHR1Melanin concentrating hormone receptor 1 (MCH1)MouseYes Yes
Neuropeptide YmNPY1RNeuropeptide Y1 receptor (Y1)MouseYes Yes
Neuropeptide YmNPY2RNeuropeptide Y2 receptor (NPY2R)MouseYes Yes
OpioidmOPRD1Opioid receptor delta (δ (murine))MouseYesYesYes
OpioidmOPRK1Opioid receptor kappa (κ (murine))MouseYesYesYes
OpioidmOPRM1Opioid receptor mu (μ (murine))MouseYesYesYes
Vasopressin and OxytocinmOXTROxytocin recepter (OT)MouseYes Yes
P2YmP2RY12P2Y Purinoceptor 12 (mP2Y12)MouseYesYesYes
P2YmP2RY6P2Y Purinoceptor 6 (P2Y6)MouseYes Yes
Neuropeptide YmPPYR1Pancreatic polypeptide receptor 1 (Y4)MouseYes Yes
Platelet-activating factor mPTAFRPlatelet-activating factor receptor (mPAF)MouseYesYesYes
ProstanoidmPTGER4Prostaglandin E receptor 4 (subtype EP4) (EP4)MouseYesYesYes
ProstanoidmPTGIRProstanoid IP1 receptor (IP1)MouseYes  
RhodopsinmRHO(P23H)Rhodopsin (Rhodopsin)MouseYes Yes
RelaxinmRXFP1Relaxin family peptide receptor 1 (RXFP1)MouseYes Yes
RelaxinmRXFP3Relaxin family peptide receptor 3 (RXFP3)MouseYesYesYes
RelaxinmRXFP4Relaxin family peptide receptor 4 (RXFP4)MouseYesYesYes
SomatostatinmSSTR2Somatostatin receptor 2 (mSST2)MouseYesYesYes
SomatostatinmSSTR5Somatostatin receptor 5 (mSRIF1B)MouseYes Yes
Trace aminemTAAR1Trace amine associated receptor 1 (mouse) (mTA1)MouseYes Yes
Tachykinin mTACR1Tachykinin receptor 1 (mNK1)MouseYes  
MelatoninMTNR1AMelatonin receptor 1A (MT1)HumanYesYesYes
MelatoninMTNR1BMelatonin receptor 1B (MT2)HumanYesYesYes
UrotensinmUTR2Urotensin II receptor (mUT)MouseYesYesYes
VIP and PACAPmVIPR1Vasoactive intestinal peptide receptor 1 (mVPAC1)MouseYesYesYes
BombesinNMBRNeuromedin B Receptor (BB1)HumanYesYesYes
Neuromedin UNMU1RNeuromedin U receptor 1 (NMU1)HumanYesYesYes
Neuropeptide B & WNPBWR1Neuropeptides B/W receptor 1 (NPBW1)HumanYesYesYes
Neuropeptide B & WNPBWR2Neuropeptides B/W receptor 2 (NPBW2)HumanYesYesYes
Neuropeptide FF & AFNPFFR1Neuropeptide FF receptor 1 (NPFF1)HumanYesYesYes
Neuropeptide SNPSR1bneuropeptide S receptor 1 (NPS receptor)HumanYesYesYes
Neuropeptide YNPY1RNeuropeptide Y receptor Y1 (Y1)HumanYesYesYes
Neuropeptide YNPY2RNeuropeptide Y receptor Y2 (Y2)HumanYesYesYes
NeurotensinNTSR1Neurotensin receptor 1 (NTS1)HumanYesYesYes
OpioidOPRD1Opioid receptor delta (δ)HumanYesYesYes
OpioidOPRK1Opioid receptor kappa (κ)HumanYesYesYes
OpioidOPRL1Opioid receptor-like receptor (NOP)HumanYesYesYes
OpioidOPRM1Opioid receptor mu (μ)HumanYesYesYes
LeukotrieneOXER1Oxoeicosanoid (OXE) receptor 1 (OXE)HumanYesYesYes
Vasopressin and OxytocinOXTROxytocin recepter (OT)HumanYesYesYes
P2YP2RY1Purinergic receptor P2Y, G-protein coupled, 1 (P2RY1)HumanYesYesYes
P2YP2RY11Purinergic receptor P2Y, G-protein coupled, 11 (P2Y11)HumanYesYesYes
P2YP2RY12Purinergic receptor P2Y, G-protein coupled, 12 (P2Y12)HumanYesYesYes
P2YP2RY2Purinergic receptor P2Y, G-protein coupled, 2 (P2Y2)HumanYesYesYes
P2YP2RY4Pyrimidinergic receptor P2Y, G-protein coupled, 4 (P2Y4)HumanYesYesYes
P2YP2RY6Pyrimidinergic receptor P2Y, G-protein coupled, 6 (P2Y6)HumanYesYesYes
Neuropeptide YPPYR1Pancreatic polypeptide receptor 1 (Y4)HumanYesYesYes
Prolactin releasing peptide receptorPRLHRProlactin releasing hormone receptor (PRRP)HumanYesYesYes
ProkineticinPROKR1Prokineticin receptor 1 (PKR1)HumanYesYesYes
ProkineticinPROKR2Prokineticin receptor 2 (PKR2)HumanYesYesYes
Platelet-activating factorPTAFRPlatelet activating receptor (PAF)HumanYesYesYes
ProstanoidPTGDRProstaglandin D2 receptor (DP1)HumanYesYesYes
ProstanoidPTGER1Prostaglandin E receptor 1 (subtype EP1) (EP1)HumanYes Yes
ProstanoidPTGER2Prostaglandin E receptor 2 (subtype EP2) (EP2)HumanYesYesYes
ProstanoidPTGER3Prostaglandin E receptor 3 (subtype EP3) (EP3)HumanYesYesYes
ProstanoidPTGER4Prostaglandin E receptor 4 (subtype EP4) (EP4)HumanYesYesYes
ProstanoidPTGFRProstaglandin F receptor (FP) (FP)HumanYesYesYes
ProstanoidPTGIRProstaglandin I2 (prostacyclin) receptor (IP) (IP1)HumanYesYesYes
Parathyroid hormonePTHR1Parathyroid hormone receptor 1 (PTH1)HumanYesYesYes
Parathyroid hormonePTHR2Parathyroid hormone receptor 2 (PTH2)HumanYesYesYes
AcetylcholinerCHRM4Cholinergic receptor, muscarinic 4 (rM4)RatYesYesYes
CannabinoidrCNR2Cannabinoid receptor 2 (CB2)RatYes Yes
ProstanoidrCRTH2Prostanoid DP2 receptor (rGPR44)RatYesYesYes
DopaminerDRD1Dopamine receptor D1 (rD1)RatYesYesYes
DopaminerDRD2LDopamine Receptor D2 (long isoform) (rD2L)RatYesYesYes
DopaminerDRD2SDopamine Receptor D2 (short isoform) (rD2S)RatYes Yes
Lysophospholipid (S1P)rEDG5Sphingosine 1-phosphate receptor 2 (rS1P2)RatYes Yes
Free Fatty AcidrFFAR1Free fatty acid receptor 1 (FFA1)RatYesYesYes
Free fatty acidrGPR120G-protein coupled receptor 120 (FFA4)RatYesYesYes
5-HydroxytryptaminerHTR2C5-hydroxytryptamine receptor 2C (HTR2C)RatYesYesYes
OpioidrOPRM1Opioid receptor mu (μ)RatYesYesYes
ProkineticinrPROKR1Prokineticin receptor 1 (rPROKR1)RatYesYesYes
ProkineticinrPROKR2Prokineticin receptor 2 (rPKR2)RatYesYesYes
ProstanoidrPTGER4Prostaglandin E receptor 4 (subtype EP4), rat (rEP4)RatYes Yes
Trace aminerTAAR1Trace amine associated receptor 1 (rat) (rTAR1)RatYes Yes
VIP and PACAPrVIPR1Vasoactive intestinal peptide receptor 1 (rVPAC1)RatYesYesYes
RelaxinRXFP1Relaxin family peptide receptor 1 (RXFP1)HumanYesYesYes
RelaxinRXFP2Relaxin family peptide receptor 2 (RXFP2)HumanYes Yes
RelaxinRXFP3Relaxin family peptide receptor 3 (RXFP3)HumanYesYesYes
RelaxinRXFP4Relaxin family peptide receptor 4 (RXFP4)HumanYesYesYes
GlucagonSCTRSecretin receptor (secretin)HumanYesYesYes
Lysophospholipid (S1P)sEDG5Sphingosine 1-phosphate receptor 2 (sS1P2)SimianYes Yes
FrizzledSMO(W535L)Smoothened, Frizzled class receptor (Smoothened)HumanYes Yes
SomatostatinSSTR1Somatostatin receptor 1 (SST1)HumanYesYesYes
SomatostatinSSTR2Somatostatin receptor 2 (SST2)HumanYesYesYes
SomatostatinSSTR3Somatostatin receptor 3 (SST3)HumanYesYesYes
SomatostatinSSTR4Somatostatin receptor 4 (SST4)HumanYesYesYes
SomatostatinSSTR5Somatostatin receptor 5 (SST5)HumanYesYesYes
Trace amineTAAR1trace amine associated receptor 1 (TA1)HumanYes Yes
TachykininTACR1Tachykinin receptor 1 (NK1)HumanYesYesYes
TachykininTACR2Tachykinin receptor 2 (NK2)HumanYesYesYes
TachykininTACR3Tachykinin receptor 3 (NK3)HumanYesYesYes
ProstanoidTBXA2RThromboxane A2 receptor (TP)HumanYesYesYes
Thyrotropin releasing hormoneTRHRThyrotropin-releasing hormone receptor (TRH1)HumanYesYesYes
Glycoprotein hormone receptorTSHR(L)Thyroid Stimulating Hormone Receptor (TSH)HumanYes Yes
UrotensinUTR2Urotensin II receptor (UT)HumanYesYesYes
VIP and PACAPVIPR1Vasoactive intestinal peptide receptor 1 (VPAC1)HumanYesYesYes
VIP and PACAPVIPR2Vasoactive intestinal peptide receptor 2 (VPAC2)HumanYesYesYes
ChemokineXCR1Chemokine (C motif) XC receptor 1 (XCR1)HumanYes Yes
+

Orphan GPCR Target List

View our complete list of Orphan GPCR Targets
FamilyGene Symbol ▲Common NameSpeciesCell LinesAssay Ready KitsService
Class B OrphanBAI1Brain-specific angiogenesis inhibitor 1 (BAI1)HumanYes Yes
Class B OrphanBAI2Brain-specific angiogenesis inhibitor 2 (BAI2)HumanYesYesYes
Class B OrphanBAI3Brain-specific angiogenesis inhibitor 3 (BAI3)HumanYesYesYes
Class A OrphancGPR91Succinic receptor, canine (cSUCNR1 )CanineYes  
Class A OrphanEBI2G protein-coupled receptor 183 (GPR183)HumanYesYesYes
Class A OrphanGHSR1bGrowth hormone secretagogue receptor 1b (GHSR1b)HumanYesYesYes
Class A OrphanGPR1G-protein coupled receptor 1 (GPR1)HumanYesYesYes
Class A OrphanGPR101G-protein coupled receptor 101 (GPR101)HumanYes Yes
Class A OrphanGPR119G-protein coupled receptor 119 (GPR119)HumanYes Yes
Class A OrphanGPR12G-protein coupled receptor 12 (GPR12)HumanYesYesYes
Class B OrphanGPR123G-protein coupled receptor 123 (GPR123)HumanYesYesYes
Class A OrphanGPR132G-protein coupled receptor 132 (GPR132)HumanYesYesYes
Class A OrphanGPR135G-protein coupled receptor 135 (GPR135)HumanYesYesYes
Class A OrphanGPR139G-protein coupled receptor 139 (GPR139)HumanYesYesYes
Class A OrphanGPR141G-protein coupled receptor 141 (GPR141)HumanYesYesYes
Class A OrphanGPR142G-protein coupled receptor 142 (GPR142)HumanYesYesYes
Class A OrphanGPR146G-protein coupled receptor 146 (GPR146)HumanYesYesYes
Class A OrphanGPR148G-protein coupled receptor 148 (GPR148)HumanYesYesYes
Class A OrphanGPR149G-protein coupled receptor 149 (GPR149)HumanYesYesYes
Class A OrphanGPR15G-protein coupled receptor 15 (GPR15)HumanYesYesYes
Class A OrphanGPR150G-protein coupled receptor 150 (GPR150)HumanYesYesYes
Class A OrphanGPR151G-protein coupled receptor 151 (GPR151)HumanYes Yes
Class A OrphanGPR152G-protein coupled receptor 152 (GPR152)HumanYes Yes
Class B OrphanGPR157G-protein coupled receptor 157 (GPR157)HumanYesYesYes
Class A OrphanGPR161G-protein coupled receptor 161 (GPR161)HumanYes Yes
Class A OrphanGPR162G-protein coupled receptor 162 (GPR162)HumanYesYesYes
Class A OrphanGPR17G-protein coupled receptor 17 (GPR17)HumanYes Yes
Class A OrphanGPR171G-protein coupled receptor 171 (GPR171)HumanYesYesYes
Class A OrphanGPR173G-protein coupled receptor 173 (GPR173)HumanYesYesYes
Class A OrphanGPR176G-protein coupled receptor 176 (GPR176)HumanYesYesYes
Class A OrphanGPR18G-protein coupled receptor 18 (GPR18)HumanYesYesYes
Class A OrphanGPR182G-protein coupled receptor 182 (GPR182)HumanYesYesYes
Class A OrphanGPR20G-protein coupled receptor 20 (GPR20)HumanYesYesYes
Class A OrphanGPR22G-protein coupled receptor 22 (GPR22)HumanYes Yes
Class A OrphanGPR23Lysophosphatidic acid receptor 4 (LPA4)HumanYesYesYes
Class A OrphanGPR25G-protein coupled receptor 25 (GPR25)HumanYesYesYes
Class A OrphanGPR26G-protein coupled receptor 26 (GPR26)HumanYesYesYes
Class A OrphanGPR27G-protein coupled receptor 27 (GPR27)HumanYesYesYes
Class A OrphanGPR3G-protein coupled receptor 3 (GPR3)HumanYesYesYes
Class A OrphanGPR31G-protein coupled receptor 31 (GPR31)HumanYesYesYes
Class A OrphanGPR32G-protein coupled receptor 32 (GPR32)HumanYesYesYes
Class A OrphanGPR35G-protein coupled receptor 35 (GPR35)HumanYesYesYes
Class A OrphanGPR37Endothelin B receptor-like (EDNRBL)HumanYesYesYes
Class A OrphanGPR37L1G protein-coupled receptor 37 like 1 (GPR37L1)HumanYesYesYes
Class A OrphanGPR39G-protein coupled receptor 39 (GPR39)HumanYesYesYes
Class A OrphanGPR4G-protein coupled receptor 4 (GPR4)HumanYesYesYes
Class A OrphanGPR45G-protein coupled receptor 45 (GPR45)HumanYesYesYes
Class A OrphanGPR50G-protein coupled receptor 50 (GPR50)HumanYesYesYes
Class A OrphanGPR52G-protein coupled receptor 52 (GPR52)HumanYesYesYes
Class A OrphanGPR55G protein-coupled receptor 55 (GPR55)HumanYesYesYes
Class A OrphanGPR6G-protein coupled receptor 6 (GPR6)HumanYesYesYes
Class A OrphanGPR61G-protein coupled receptor 61 (GPR61)HumanYesYesYes
Class A OrphanGPR65G-protein coupled receptor 65 (GPR65)HumanYesYesYes
Class A OrphanGPR75G-protein coupled receptor 75 (GPR75)HumanYesYesYes
Class A OrphanGPR78G-protein coupled receptor 78 (GPR78)HumanYesYesYes
Class A OrphanGPR79G protein-coupled receptor 79 pseudogene (GPR79)HumanYesYesYes
Class A OrphanGPR83G-protein coupled receptor 83 (GPR83)HumanYesYesYes
Class A OrphanGPR84G-protein coupled receptor 84 (GPR84)HumanYes Yes
Class A OrphanGPR85G-protein coupled receptor 85 (GPR85)HumanYesYesYes
Class A OrphanGPR88G-protein coupled receptor 88 (GPR88)HumanYesYesYes
Class B OrphanGPR97G-protein coupled receptor 97 (GPR97)HumanYesYesYes
Class A OrphanLGR4Leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4)HumanYesYesYes
Class A OrphanLGR5Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5)HumanYesYesYes
Class A OrphanLGR6Leucine-rich repeat-containing G protein-coupled receptor 6 (LGR6)HumanYesYesYes
Class A OrphanmEBI2G-protein coupled receptor 183 (GPR183)MouseYesYesYes
Class A OrphanmGPR1G-Protein Coupled Receptor 1 (mGPR1)MouseYes Yes
Class A OrphanmGPR84G-protein coupled receptor 84, Mouse (GPR84)MouseYes Yes
Class A OrphanMRGPRDMAS-related GPR, member D (MRGPRD)HumanYesYesYes
Class A OrphanMRGPREMAS-related GPR, member E (MRGPRE)HumanYesYesYes
Class A OrphanMRGPRFMAS-related GPR, member F (MRGPRF)HumanYesYesYes
Class A OrphanMRGPRX1MAS-related GPR, member X1 (MRGPRX1)HumanYes Yes
Class A OrphanMRGPRX2MAS-related GPR, member X2 (MRGX2)HumanYesYesYes
Class A OrphanMRGPRX4MAS-related GPR, member X4 (MRGPRX4)HumanYesYesYes
Class A OrphanOPN5Opsin 5 (OPN5)HumanYesYesYes
Class A OrphanOXGR1Oxoglutarate (alpha-ketoglutarate) receptor 1 (OXGR1)HumanYesYesYes
Class A OrphanP2RY8Purinergic receptor P2Y, G-protein coupled, 8 (P2RY8)HumanYesYesYes
Class A OrphanrGPR35G-protein coupled receptor 35 (rGPR35)RatYesYesYes
Class A OrphanTAAR5Trace amine associated receptor 5 (TAAR5)HumanYesYesYes
+

Kinase Target List

View our complete list of Kinase Targets
GroupEntrez Gene SymbolKGS ▲Common NameSpeciesCell LinesAssay Ready KitsService
OtherAAK1AAK1AP2 associated kinase 1 (AAK1)Human  Yes
Non-receptor tyrosine kinaseABL1ABL1Homo sapiens ABL proto-oncogene 1, non-receptor tyrosine-protein kinase (ABL1), transcript variant A (ABL1)Human Yes 
TKABL1ABL1(E255K)-phosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1(E255K)-phosphorylated)Human  Yes
TKABL1ABL1(F317I)-nonphosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1(F317I)-nonphosphorylated)Human  Yes
TKABL1ABL1(F317I)-phosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1(F317I)-phosphorylated)Human  Yes
TKABL1ABL1(F317L)-nonphosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1(F317L)-nonphosphorylated)Human  Yes
TKABL1ABL1(F317L)-phosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1(F317L)-phosphorylated)Human  Yes
TKABL1ABL1(H396P)-nonphosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1(H396P)-nonphosphorylated)Human  Yes
TKABL1ABL1(H396P)-phosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1(H396P)-phosphorylated)Human  Yes
TKABL1ABL1(M351T)-phosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1(M351T)-phosphorylated)Human  Yes
TKABL1ABL1(Q252H)-nonphosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1(Q252H)-nonphosphorylated)Human  Yes
TKABL1ABL1(Q252H)-phosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1(Q252H)-phosphorylated)Human  Yes
TKABL1ABL1(T315I)-nonphosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1(T315I)-nonphosphorylated)Human  Yes
TKABL1ABL1(T315I)-phosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1(T315I)-phosphorylated)Human  Yes
TKABL1ABL1(Y253F)-phosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1(Y253F)-phosphorylated)Human  Yes
TKABL1ABL1-nonphosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1-nonphosphorylated)Human  Yes
TKABL1ABL1-phosphorylatedc-abl oncogene 1, receptor tyrosine kinase (ABL1-phosphorylated)Human  Yes
TKABL2ABL2v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) (ABL2)Human  Yes
TKLACVR1ACVR1activin A receptor, type I (ACVR1)Human  Yes
TKLACVR1BACVR1Bactivin A receptor, type IB (ACVR1B)Human  Yes
Ser/Thr KinaseACVR1B/BMPR2ACVR1B/BMPR2Activin A receptor type IB (ALK4)HumanYesYes 
Ser/Thr KinaseACVR1C/ACVR2ACVR1C/ACVR2activin A receptor, type IC (ALK7)HumanYesYes 
Ser/Thr KinaseACVR1C/ACVR2BACVR1C/ACVR2Bactivin A receptor, type IC (ALK7)HumanYesYes 
Ser/Thr KinaseACVR2/ACVR1ACVR2/ACVR1activin A receptor, type IIA (ACVR2A)HumanYes  
TKLACVR2AACVR2Aactivin A receptor, type IIA (ACVR2A)Human  Yes
TKLACVR2BACVR2Bactivin A receptor, type IIB (ACVR2B)Human  Yes
TKLACVRL1ACVRL1activin A receptor type II-like 1 (ACVRL1)Human  Yes
Ser/Thr KinaseACVRL1/ACVR2ACVRL1/ACVR2Activin A receptor type II-like 1 (Alk1)HumanYesYes 
Ser/Thr KinaseACVRL1/ACVR2BACVRL1/ACVR2BActivin A receptor type II-like 1 (Alk1)HumanYesYes 
Ser/Thr KinaseACVRL1/BMPR2ACVRL1/BMPR2Activin A receptor type II-like 1 (Alk1)HumanYesYes 
AtypicalCABC1ADCK3coenzyme Q8A (ADCK3)Human  Yes
AtypicalADCK4ADCK4aarF domain containing kinase 4 (ADCK4)Human  Yes
AGCAKT1AKT1v-akt murine thymoma viral oncogene homolog 1 (AKT1)Human  Yes
AGCAKT2AKT2v-akt murine thymoma viral oncogene homolog 2 (AKT2)Human  Yes
AGCAKT3AKT3AKT serine/threonine kinase 3 (AKT3)Human  Yes
TKALKALKanaplastic lymphoma receptor tyrosine kinase (ALK)Human  Yes
TKALKALK(1151Tins)anaplastic lymphoma receptor tyrosine kinase (ALK(1151Tins))Human  Yes
TKALKALK(C1156Y)anaplastic lymphoma receptor tyrosine kinase (ALK(C1156Y))Human  Yes
TKALKALK(F1174L)anaplastic lymphoma receptor tyrosine kinase (ALK(F1174L))Human  Yes
TKALKALK(L1196M)anaplastic lymphoma receptor tyrosine kinase (ALK(L1196M))Human  Yes
CAMKPRKAA1AMPK-alpha1protein kinase, AMP-activated, alpha 2 catalytic subunit (AMPK-alpha1)Human  Yes
CAMKPRKAA2AMPK-alpha2protein kinase, AMP-activated, alpha 2 catalytic subunit (AMPK-alpha2)Human  Yes
TKLANKK1ANKK1ankyrin repeat and kinase domain containing 1 (ANKK1)Human  Yes
CAMKNUAK1ARK5NUAK family, SNF1-like kinase, 1 (ARK5)Human  Yes
STEMAP3K5ASK1mitogen-activated protein kinase kinase kinase 5 (ASK1)Human  Yes
STEMAP3K6ASK2mitogen-activated protein kinase kinase kinase 6 (ASK2)Human  Yes
OtherAURKAAURKAaurora kinase A (AURKA)Human  Yes
OtherAURKBAURKBaurora kinase B (AURKB)Human  Yes
OtherAURKCAURKCaurora kinase C (AURKC)Human  Yes
Receptor tyrosine kinaseAXLAXLAXL receptor tyrosine kinase (AXL)HumanYes Yes
OtherBMP2KBIKEBMP2 inducible kinase (BIKE)Human  Yes
Cytosolic tyrosine kinaseBLKBLKB lymphoid tyrosine kinase (BLK)HumanYesYesYes
TKLBMPR1ABMPR1Abone morphogenetic protein receptor, type IA (BMPR1A)Human  Yes
Ser/Thr KinaseBMPR1A/ACVR2BMPR1A/ACVR2bone morphogenetic protein receptor, type IA (ALK3)HumanYesYes 
Ser/Thr KinaseBMPR1A/ACVR2BBMPR1A/ACVR2Bbone morphogenetic protein receptor, type IA (ALK3)HumanYes  
Ser/Thr KinaseBMPR1A/BMPR2BMPR1A/BMPR2bone morphogenetic protein receptor, type IA (ALK3)HumanYesYes 
TKLBMPR1BBMPR1Bbone morphogenetic protein receptor, type IB (BMPR1B)Human  Yes
Ser/Thr KinaseBMPR1B/ACVR2BMPR1B/ACVR2bone morphogenetic protein receptor, type IB (ALK6)HumanYesYes 
Ser/Thr KinaseBMPR1B/ACVR2BBMPR1B/ACVR2Bbone morphogenetic protein receptor, type IB (ALK6)HumanYes  
Ser/Thr KinaseBMPR1B/BMPR2BMPR1B/BMPR2bone morphogenetic protein receptor, type IB (ALK6)HumanYes  
TKLBMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2)Human  Yes
TKBMXBMXBMX non-receptor tyrosine kinase (BMX)Human  Yes
TKLBRAFBRAFv-raf murine sarcoma viral oncogene homolog B1 (BRAF)Human  Yes
TKLBRAFBRAF(V600E)v-raf murine sarcoma viral oncogene homolog B1 (BRAF(V600E))Human  Yes
TKPTK6BRKprotein tyrosine kinase 6 (BRK)Human  Yes
CAMKBRSK1BRSK1BR serine/threonine kinase 1 (BRSK1)Human  Yes
CAMKBRSK2BRSK2BR serine/threonine kinase 2 (BRSK2)Human  Yes
Cytosolic tyrosine kinaseBTKBTKBruton agammaglobulinemia tyrosine kinase (BTK)HumanYesYesYes
OtherBUB1BUB1BUB1 mitotic checkpoint serine/threonine kinase (BUB1)Human  Yes
CAMKCAMK1CAMK1calcium/calmodulin-dependent protein kinase I (CAMK1)Human  Yes
CAMKPNCKCAMK1Bpregnancy up-regulated nonubiquitous CaM kinase (CAMK1B)Human  Yes
CAMKCAMK1DCAMK1Dcalcium/calmodulin-dependent protein kinase ID (CAMK1D)Human  Yes
CAMKCAMK1GCAMK1Gcalcium/calmodulin-dependent protein kinase IG (CAMK1G)Human  Yes
CAMKCAMK2ACAMK2Acalcium/calmodulin-dependent protein kinase II alpha (CAMK2A)Human  Yes
CAMKCAMK2BCAMK2Bcalcium/calmodulin-dependent protein kinase II beta (CAMK2B)Human  Yes
CAMKCAMK2DCAMK2Dcalcium/calmodulin-dependent protein kinase II delta (CAMK2D)Human  Yes
CAMKCAMK2GCAMK2Gcalcium/calmodulin-dependent protein kinase II gamma (CAMK2G)Human  Yes
CAMKCAMK4CAMK4calcium/calmodulin-dependent protein kinase IV (CAMK4)Human  Yes
OtherCAMKK1CAMKK1calcium/calmodulin-dependent protein kinase kinase 1, alpha (CAMKK1)Human  Yes
OtherCAMKK2CAMKK2calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2)Human  Yes
CAMKCASKCASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family) (CASK)Human  Yes
CMGCCDK11BCDC2L1cyclin-dependent kinase 11B (CDC2L1)Human  Yes
CMGCCDC2L2CDC2L2cyclin-dependent kinase 11A (CDC2L2)Human  Yes
CMGCCDK13CDC2L5cyclin-dependent kinase 13 (CDC2L5)Human  Yes
CMGCCDK1CDK1cyclin-dependent kinase 1 [ Homo sapiens (human) ] (CDK1)Human  Yes
CMGCCDK10CDK10cyclin-dependent kinase 10 [ Homo sapiens (human) ] (CDK10)Human  Yes
CMGCCDK19CDK11cyclin-dependent kinase 19 (CDK11)Human  Yes
CMGCCDK12CDK12cyclin-dependent kinase 12 isoform 2 [Homo sapiens] (CDK12)Human  Yes
CMGCCDK2CDK2cyclin-dependent kinase 2 (CDK2)Human  Yes
CMGCCDK20CDK20 cyclin-dependent kinase 20 [ Homo sapiens (human) ] (CDK20)Human  Yes
CMGCCDK3CDK3cyclin-dependent kinase 3 (CDK3)Human  Yes
CMGCCDK4CDK4cyclin-dependent kinase 4 (CDK4)Human  Yes
CMGCCDK4CDK4-cyclinD1cyclin-dependent kinase 4 (CDK4-cyclinD1)Human  Yes
CMGCCDK4CDK4-cyclinD1(F93L)cyclin-dependent kinase 4 (CDK4-cyclinD1(F93L))Human  Yes
CMGCCDK4CDK4-cyclinD3cyclin-dependent kinase 4 (CDK4-cyclinD3)Human  Yes
CMGCCDK5CDK5cyclin-dependent kinase 5 (CDK5)Human  Yes
CMGCCDK6CDK6cyclin-dependent kinase 6 [ Homo sapiens (human) ] (CDK6)Human  Yes
CMGCCDK7CDK7cyclin-dependent kinase 7 (CDK7)Human  Yes
CMGCCDK8CDK8cyclin-dependent kinase 8 (CDK8)Human  Yes
CMGCCDK9CDK9cyclin-dependent kinase 9 (CDK9)Human  Yes
CMGCCDKL1CDKL1cyclin-dependent kinase-like 1 (CDC2-related kinase) (CDKL1)Human  Yes
CMGCCDKL2CDKL2cyclin-dependent kinase-like 2 (CDC2-related kinase) (CDKL2)Human  Yes
CMGCCDKL3CDKL3cyclin-dependent kinase-like 3 (CDKL3)Human  Yes
CMGCCDKL5CDKL5cyclin-dependent kinase-like 5 (CDKL5)Human  Yes
CAMKCHEK1CHEK1checkpoint kinase 1 (CHEK1)Human  Yes
CAMKCHEK2CHEK2checkpoint kinase 2 (CHEK2)Human  Yes
Receptor Tyrosine KinasecINSRacINSRaInsulin receptor, isoform A (INSR)CynoYes Yes
Receptor Tyrosine KinasecINSRbcINSRbInsulin receptor, isoform B (INSR)Macaca fascicularisYes Yes
AGCCITCITcitron (rho-interacting, serine/threonine kinase 21) (CIT)Human  Yes
Receptor Tyrosine Kinasec-KITc-KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT)HumanYesYesYes
CDC-like KinaseCLK1CLK1CDC-Like Kinase 1 (CLK1)HumanYesYesYes
CDC-like KinaseCLK2CLK2CDC-Like Kinase 2 (CLK2)HumanYesYesYes
CMGCCLK3CLK3CDC-like kinase 3 (CLK3)Human  Yes
CMGCCLK4CLK4CDC-like kinase 4 (CLK4)Human  Yes
Receptor Tyrosine Kinasec-MET/c-METc-MET/c-METHepatocyte growth factor receptor (MET)HumanYes  
Receptor Tyrosine Kinasec-Ret-GFRα1c-Ret-GFRα1Proto-oncogene tyrosine-protein kinase receptor Ret (RET)HumanYesYesYes
Receptor Tyrosine Kinasec-Ret-GFRα2c-Ret-GFRα2Proto-oncogene tyrosine-protein kinase receptor Ret (RET)HumanYesYesYes
Receptor Tyrosine KinaseCSF1RCSF1Rcolony-stimulating factor 1 receptor (CSF1R)HumanYesYesYes
Receptor Tyrosine KinaseCSF1R/CSF1RCSF1R/CSF1Rcolony stimulating factor 1 receptor (CSF1R/CSF1R)HumanYesYes 
TKCSF1RCSF1R-autoinhibitedcolony stimulating factor 1 receptor (CSF1R-autoinhibited)Human  Yes
Cytosolic Tyrosine KinaseCSF3R-JAK1CSF3R-JAK1colony stimulating factor 3 receptor (CSF3R-JAK1)HumanYesYesYes
TKCSKCSKc-src tyrosine kinase (CSK)Human  Yes
CK1CSNK1A1CSNK1A1casein kinase 1, alpha 1 (CSNK1A1)Human  Yes
CK1CSNK1A1LCSNK1A1Lcasein kinase 1, alpha 1-like (CSNK1A1L)Human  Yes
Protein KinaseCSNK1DCSNK1Dcasein kinase 1, delta (CSNK1D)HumanYesYesYes
CK1CSNK1ECSNK1Ecasein kinase 1, epsilon (CSNK1E)Human  Yes
CK1CSNK1G1CSNK1G1casein kinase 1, gamma 1 (CSNK1G1)Human  Yes
CK1CSNK1G2CSNK1G2casein kinase 1, gamma 2 (CSNK1G2)Human  Yes
CK1CSNK1G3CSNK1G3casein kinase 1, gamma 3 (CSNK1G3)Human  Yes
OtherCSNK2A1CSNK2A1casein kinase 2, alpha 1 polypeptide (CSNK2A1)Human  Yes
OtherCSNK2A2CSNK2A2casein kinase 2, alpha prime polypeptide (CSNK2A2)Human  Yes
TKMATKCTKmegakaryocyte-associated tyrosine kinase (CTK)Human  Yes
CAMKDAPK1DAPK1death-associated protein kinase 1 (DAPK1)Human  Yes
CAMKDAPK2DAPK2death-associated protein kinase 2 (DAPK2)Human  Yes
CAMKDAPK3DAPK3death-associated protein kinase 3 (DAPK3)Human  Yes
CAMKDCLK1DCAMKL1doublecortin-like kinase 1 (DCAMKL1)Human  Yes
CAMKDCLK2DCAMKL2doublecortin-like kinase 2 (DCAMKL2)Human  Yes
CAMKDCLK3DCAMKL3doublecortin-like kinase 3 (DCAMKL3)Human  Yes
Receptor Tyrosine KinaseDDR1DDR1Discoidin domain receptor 1 (CD167a)HumanYesYesYes
TKDDR2DDR2(T654M)discoidin domain receptor tyrosine kinase 2 (DDR2(T654M))Human  Yes
TKLMAP3K12DLKmitogen-activated protein kinase kinase kinase 12 (DLK)Human  Yes
AGCDMPKDMPKdystrophia myotonica-protein kinase (DMPK)Human  Yes
AGCCDC42BPGDMPK2CDC42 binding protein kinase gamma (DMPK-like) (DMPK2)Human  Yes
CAMKSTK17ADRAK1serine/threonine kinase 17a (DRAK1)Human  Yes
CAMKSTK17BDRAK2serine/threonine kinase 17b (DRAK2)Human  Yes
CMGCDYRK1ADYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A)Human  Yes
CMGCDYRK1BDYRK1Bdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B (DYRK1B)Human  Yes
CMGCDYRK2DYRK2dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2)Human  Yes
TKEGFREGFRepidermal growth factor receptor (EGFR)Human  Yes
TKEGFREGFR(E746-A750del)epidermal growth factor receptor (EGFR(E746-A750del))Human  Yes
TKEGFREGFR(G719C)epidermal growth factor receptor (EGFR(G719C))Human  Yes
TKEGFREGFR(G719S)epidermal growth factor receptor (EGFR(G719S))Human  Yes
TKEGFREGFR(L747-E749del, A750P)epidermal growth factor receptor (EGFR(L747-E749del, A750P))Human  Yes
TKEGFREGFR(L747-S752del, P753S)epidermal growth factor receptor (EGFR(L747-S752del, P753S))Human  Yes
TKEGFREGFR(L747-T751del,Sins)epidermal growth factor receptor (EGFR(L747-T751del,Sins))Human  Yes
TKEGFREGFR(L858R)epidermal growth factor receptor (EGFR(L858R))Human  Yes
TKEGFREGFR(L858R,T790M)epidermal growth factor receptor (EGFR(L858R,T790M))Human  Yes
TKEGFREGFR(L861Q)epidermal growth factor receptor (EGFR(L861Q))Human  Yes
TKEGFREGFR(S752-I759del)epidermal growth factor receptor (EGFR(S752-I759del))Human  Yes
TKEGFREGFR(T790M)epidermal growth factor receptor (EGFR(T790M))Human  Yes
Receptor Tyrosine KinaseEGFR/EGFREGFR/EGFREpidermal growth factor receptor (EGFR)HumanYesYes 
Receptor Tyrosine KinaseEGFR/ErbB2EGFR/ErbB2Epidermal growth factor receptor (EGFR)HumanYesYes 
OtherEIF2AK1EIF2AK1eukaryotic translation initiation factor 2-alpha kinase 1 (EIF2AK1)Human  Yes
TKEPHA1EPHA1EPH receptor A1 (EPHA1)Human  Yes
TKEPHA2EPHA2EPH receptor A2 (EPHA2)Human  Yes
TKEPHA3EPHA3EPH receptor A3 (EPHA3)Human  Yes
Receptor Tyrosine KinaseEphA4EphA4EPH receptor A4 (EphA4)HumanYes Yes
Receptor Tyrosine KinaseEphA5EphA5Ephrin type-A receptor 5 (EphA5)HumanYes Yes
TKEPHA6EPHA6EPH receptor A6 (EPHA6)Human  Yes
Receptor Tyrosine KinaseEphA7EphA7Ephrin type-A receptor 7 (EphA7)HumanYesYesYes
TKEPHA8EPHA8EPH receptor A8 (EPHA8)Human  Yes
Receptor Tyrosine KinaseEphB1EphB1Ephrin type-B receptor 1 (EphB1)HumanYesYesYes
Receptor Tyrosine KinaseEphB2EphB2Ephrin type-B receptor 2 (EphB2)HumanYesYesYes
Receptor Tyrosine KinaseEphB3EphB3Ephrin type-B receptor 3 (EphB3)HumanYesYesYes
Receptor Tyrosine KinaseEphB4EphB4Ephrin type-B receptor 4 (EphB4)HumanYesYesYes
TKEPHB6EPHB6EPH receptor B6 (EPHB6)Human  Yes
Receptor Tyrosine KinaseErbB1ErbB1v-erb-b2 erythroblastic leukemia viral oncogene homolog 1 (EGFR)HumanYes Yes
TKERBB2ERBB2erb-b2 receptor tyrosine kinase 2 (ERBB2)Human  Yes
Receptor Tyrosine KinaseErbB2/ErbB3ErbB2/ErbB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 (HER2)HumanYes  
Receptor Tyrosine KinaseErbB2/ErbB4ErbB2/ErbB4v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 (HER2)HumanYesYes 
Receptor Tyrosine KinaseErbB2-ErbB3ErbB2-ErbB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 (HER2)HumanYesYesYes
TKERBB3ERBB3erb-b2 receptor tyrosine kinase 3Human  Yes
Receptor Tyrosine KinaseErbB4ErbB4erb-b2 receptor tyrosine kinase 4HumanYes Yes
Receptor Tyrosine KinaseErbB4/ErbB4ErbB4/ErbB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (HER4)HumanYesYes 
CMGCMAPK3ERK1mitogen-activated protein kinase 3 (ERK1)Human  Yes
CMGCMAPK3ERK1(Q122L)mitogen-activated protein kinase 3 (ERK1(Q122L))Human  Yes
CMGCMAPK1ERK2mitogen-activated protein kinase 1 (ERK2)Human  Yes
CMGCMAPK6ERK3mitogen-activated protein kinase 6 (ERK3)Human  Yes
CMGCMAPK4ERK4mitogen-activated protein kinase 4 (ERK4)Human  Yes
CMGCMAPK7ERK5mitogen-activated protein kinase 7 (ERK5)Human  Yes
CMGCMAPK15ERK8mitogen-activated protein kinase 15 (ERK8)Human  Yes
OtherERN1ERN1endoplasmic reticulum to nucleus signaling 1 (ERN1)Human  Yes
TKPTK2FAKPTK2 protein tyrosine kinase 2 (FAK)Human  Yes
TKFERFERfer (fps/fes related) tyrosine kinase (FER)Human  Yes
TKFESFESfeline sarcoma oncogene (FES)Human  Yes
Receptor Tyrosine KinaseFGFR1FGFR1Fibroblast growth factor receptor 1 (FGFR1)HumanYesYesYes
Receptor Tyrosine KinaseFGFR1-β-KlothoFGFR1-β-KlothoFibroblast growth factor receptor 1 (FGFR1)HumanYes Yes
Receptor Tyrosine KinaseFGFR2FGFR2Epidermal growth factor receptor (EGFR)HumanYesYesYes
TKFGFR2FGFR2(N550K)fibroblast growth factor receptor 2 (FGFR2(N550K))Human  Yes
TKFGFR3FGFR3fibroblast growth factor receptor 3 (FGFR3)Human  Yes
Receptor Tyrosine KinaseFGFR3(G380R)/FGFR3(G380R)FGFR3(G380R)/FGFR3(G380R)Fibroblast growth factor receptor 3, G380R mutant (FGFR3)HumanYes  
TKFGFR3FGFR3(G697C)fibroblast growth factor receptor 3 (FGFR3(G697C))Human  Yes
TKFGFR3FGFR3(K650E)fibroblast growth factor receptor 3 (FGFR3(K650E))Human  Yes
TKFGFR3FGFR3(V555M)fibroblast growth factor receptor 3 (FGFR3(V555M))Human  Yes
Receptor Tyrosine KinaseFGFR3/FGFR3FGFR3/FGFR3Fibroblast growth factor receptor 3 (FGFR3/FGFR3)HumanYes  
TKFGFR4FGFR4fibroblast growth factor receptor 4 (FGFR4)HumanYesYesYes
Receptor Tyrosine KinaseFGFR4FGFR4Fibroblast growth factor receptor 4 (FGFR4)HumanYesYesYes
Receptor Tyrosine KinaseFGFR4-β-KlothoFGFR4-β-KlothoFibroblast growth factor receptor 4 (FGFR4)HumanYesYesYes
Cytosolic tyrosine kinaseFGRFGRFGR proto-oncogene, Src family tyrosine kinase (FGR)HumanYesYesYes
TKFLT1FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (FLT1)Human  Yes
Receptor Tyrosine KinaseFLT3FLT3Fms-related tyrosine kinase 3 (FLT3)HumanYesYesYes
TKFLT3FLT3(D835H)fms-related tyrosine kinase 3 (FLT3(D835H))Human  Yes
TKFLT3FLT3(D835V)fms-related tyrosine kinase 3 (FLT3(D835V))Human  Yes
TKFLT3FLT3(D835Y)fms-related tyrosine kinase 3 (FLT3(D835Y))Human  Yes
TKFLT3FLT3(ITD)fms-related tyrosine kinase 3 (FLT3(ITD))Human  Yes
TKFLT3FLT3(ITD,D835V)fms-related tyrosine kinase 3 (FLT3(ITD,D835V))Human  Yes
TKFLT3FLT3(ITD,F691L)fms-related tyrosine kinase 3 (FLT3(ITD,F691L))Human  Yes
TKFLT3FLT3(K663Q)fms-related tyrosine kinase 3 (FLT3(K663Q))Human  Yes
TKFLT3FLT3(N841I)fms-related tyrosine kinase 3 (FLT3(N841I))Human  Yes
TKFLT3FLT3(R834Q)fms-related tyrosine kinase 3 (FLT3(R834Q))Human  Yes
TKFLT3FLT3-autoinhibitedfms-related tyrosine kinase 3 (FLT3-autoinhibited)Human  Yes
Receptor Tyrosine KinaseFLT4FLT4fms-related tyrosine kinase 4 (FLT4)HumanYesYesYes
TKFRKFRKfyn-related kinase (FRK)Human  Yes
TKFYNFYNFYN oncogene related to SRC, FGR, YES (FYN)Human  Yes
OtherGAKGAKcyclin G associated kinase (GAK)Human  Yes
OtherEIF2AK4GCN2(Kin.Dom.2,S808G)eukaryotic translation initiation factor 2 alpha kinase 4 (GCN2(Kin.Dom.2,S808G))Human  Yes
Cytosolic Tyrosine KinaseGHR-JAK1GHR-JAK1Growth hormone receptor (GHR-JAK1)HumanYesYesYes
Cytosolic Tyrosine KinaseGHR-JAK2GHR-JAK2Growth hormone receptor (GHR-JAK2)HumanYesYesYes
AGCGRK1GRK1G protein-coupled receptor kinase 1 (GRK1)Human  Yes
AGCADRBK1GRK2adrenergic, beta, receptor kinase 1 [ Homo sapiens (human) ] (GRK2)Human  Yes
AGCADRBK2GRK3adrenergic, beta, receptor kinase 2 [ Homo sapiens (human) ] (GRK3)Human  Yes
AGCGRK4GRK4G protein-coupled receptor kinase 4 (GRK4)Human  Yes
AGCGRK7GRK7G protein-coupled receptor kinase 7 (GRK7)Human  Yes
CMGCGSK3AGSK3Aglycogen synthase kinase 3 alpha (GSK3A)Human  Yes
CMGCGSK3BGSK3Bglycogen synthase kinase 3 beta (GSK3B)Human  Yes
OtherGSG2HASPINgerm cell associated 2 (haspin) (HASPIN)Human  Yes
Cytosolic tyrosine kinaseHCKHCKHemopoietic cell kinase (HCK)HumanYesYesYes
CMGCHIPK1HIPK1homeodomain interacting protein kinase 1 (HIPK1)Human  Yes
CMGCHIPK2HIPK2homeodomain interacting protein kinase 2 (HIPK2)Human  Yes
CMGCHIPK3HIPK3homeodomain interacting protein kinase 3 (HIPK3)Human  Yes
CMGCHIPK4HIPK4homeodomain interacting protein kinase 4 (HIPK4)Human  Yes
STEMAP4K1HPK1mitogen-activated protein kinase kinase kinase kinase 1 (HPK1)Human  Yes
CAMKHUNKHUNKhormonally up-regulated Neu-associated kinase (HUNK)Human  Yes
CMGCICKICKintestinal cell (MAK-like) kinase (ICK)Human  Yes
Receptor Tyrosine KinaseIGF1RIGF1RInsulin-like growth factor 1 receptor (IGF1R)HumanYesYesYes
OtherCHUKIKK-alphaconserved helix-loop-helix ubiquitous kinase (IKK-alpha)Human  Yes
OtherIKBKBIKK-betainhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKK-beta)Human  Yes
OtherIKBKEIKK-epsiloninhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (IKK-epsilon)Human  Yes
TKINSRINSRinsulin receptor (INSR)Human  Yes
Receptor Tyrosine KinaseINSRaINSRaInsulin receptor, isoform A (INSR)HumanYes Yes
Receptor Tyrosine KinaseINSRbINSRbInsulin receptor, isoform B (INSR)HumanYesYesYes
TKINSRRINSRRinsulin receptor-related receptor (INSRR)Human  Yes
TKLIRAK1IRAK1interleukin-1 receptor-associated kinase 1 (IRAK1)Human  Yes
TKLIRAK2IRAK2interleukin-1 receptor-associated kinase 2 [ Homo sapiens (human) ] (IRAK2)Human  Yes
TKLIRAK3IRAK3interleukin-1 receptor-associated kinase 3 (IRAK3)Human  Yes
TKLIRAK4IRAK4interleukin-1 receptor-associated kinase 4 (IRAK4)Human  Yes
TKITKITKIL2-inducible T-cell kinase (ITK)Human  Yes
TKJAK1JAK1(JH1domain-catalytic)Janus kinase 1 (JAK1(JH1domain-catalytic))Human  Yes
TKJAK1JAK1(JH2domain-pseudokinase)Janus kinase 1 (JAK1(JH2domain-pseudokinase))Human  Yes
TKJAK2JAK2(JH1domain-catalytic)Janus kinase 2 (JAK2(JH1domain-catalytic))Human  Yes
Cytosolic tyrosine kinaseJAK3JAK3Janus kinase 3 (JAK3)HumanYesYesYes
TKJAK3JAK3(JH1domain-catalytic)Janus kinase 3 (JAK3(JH1domain-catalytic))Human  Yes
CMGCMAPK8JNK1mitogen-activated protein kinase 8 (JNK1)Human  Yes
CMGCMAPK9JNK2mitogen-activated protein kinase 9 (JNK2)Human  Yes
CMGCMAPK10JNK3mitogen-activated protein kinase 10 (JNK3)Human  Yes
Receptor Tyrosine KinaseKDRKDRKinase Insert Domain Receptor (VEGFR2)HumanYesYesYes
Receptor Tyrosine KinaseKDR/KDRKDR/KDRKinase Insert Domain Receptor (VEGFR2)HumanYesYes 
TKKITKITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT)Human  Yes
TKKITKIT(A829P)v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT(A829P))Human  Yes
TKKITKIT(D816H)v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT(D816H))Human  Yes
TKKITKIT(D816V)v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT(D816V))Human  Yes
TKKITKIT(L576P)v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT(L576P))Human  Yes
TKKITKIT(V559D)v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT(V559D))Human  Yes
TKKITKIT(V559D,T670I)v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT(V559D,T670I))Human  Yes
TKKITKIT(V559D,V654A)v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT(V559D,V654A))Human  Yes
TKKITKIT-autoinhibitedv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT-autoinhibited)Human  Yes
AGCLATS1LATS1large tumor suppressor kinase 1 (LATS1)Human  Yes
AGCLATS2LATS2large tumor suppressor kinase 2 (LATS2)Human  Yes
TKLCKLCKlymphocyte-specific protein tyrosine kinase (LCK)HumanYes Yes
TKLLIMK1LIMK1LIM domain kinase 1 (LIMK1)Human  Yes
TKLLIMK2LIMK2LIM domain kinase 2 (LIMK2)Human  Yes
CAMKSTK11LKB1serine/threonine kinase 11 (LKB1)Human  Yes
STESTK10LOKserine/threonine kinase 10 (LOK)Human  Yes
TKLLRRK2LRRK2leucine-rich repeat kinase 2 (LRRK2)Human  Yes
TKLLRRK2LRRK2(G2019S)leucine-rich repeat kinase 2 (LRRK2(G2019S))Human  Yes
TKLTKLTKleukocyte receptor tyrosine kinase (LTK)Human  Yes
TKLYNLYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog (LYN)Human  Yes
TKLMAP3K13LZKmitogen-activated protein kinase kinase kinase 13 (LZK)Human  Yes
CMGCMAKMAKmale germ cell-associated kinase (MAK)Human  Yes
STEMAP3K1MAP3K1mitogen-activated protein kinase kinase kinase 1 (MAP3K1)Human  Yes
STEMAP3K15MAP3K15mitogen-activated protein kinase kinase kinase 15 (MAP3K15)Human  Yes
STEMAP3K2MAP3K2mitogen-activated protein kinase kinase kinase 2 (MAP3K2)Human  Yes
STEMAP3K3MAP3K3mitogen-activated protein kinase kinase kinase 3 (MAP3K3)Human  Yes
STEMAP3K4MAP3K4mitogen-activated protein kinase kinase kinase 4 (MAP3K4)Human  Yes
STEMAP4K2MAP4K2mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2)Human  Yes
STEMAP4K3MAP4K3mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3)Human  Yes
STEMAP4K4MAP4K4mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)Human  Yes
STEMAP4K5MAP4K5mitogen-activated protein kinase kinase kinase kinase 5 (MAP4K5)Human  Yes
CAMKMAPKAPK2MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2)Human  Yes
CAMKMAPKAPK5MAPKAPK5mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5)Human  Yes
CAMKMARK1MARK1MAP/microtubule affinity-regulating kinase 1 (MARK1)Human  Yes
CAMKMARK2MARK2MAP/microtubule affinity-regulating kinase 2 (MARK2)Human  Yes
CAMKMARK3MARK3MAP/microtubule affinity-regulating kinase 3 (MARK3)Human  Yes
CAMKMARK4MARK4MAP/microtubule affinity-regulating kinase 4 (MARK4)Human  Yes
AGCMAST1MAST1microtubule associated serine/threonine kinase 1 (MAST1)Human  Yes
Extracellular signal-regulated kinaseMEK1MEK1Mitogen-activated protein kinase kinase 1 (MAP2K1)HumanYesYesYes
STEMAP2K2MEK2mitogen-activated protein kinase kinase 2 (MEK2)Human  Yes
STEMAP2K3MEK3mitogen-activated protein kinase kinase 3 (MEK3)Human  Yes
STEMAP2K4MEK4mitogen-activated protein kinase kinase 4 (MEK4)Human  Yes
STEMAP2K5MEK5mitogen-activated protein kinase kinase 5 (MEK5)Human  Yes
STEMAP2K6MEK6mitogen-activated protein kinase kinase 6 (MEK6)Human  Yes
CAMKMELKMELKmaternal embryonic leucine zipper kinase (MELK)Human  Yes
TKMERTKMERTKc-mer proto-oncogene tyrosine kinase (MERTK)Human  Yes
TKMETMETmet proto-oncogene (hepatocyte growth factor receptor) (MET)Human  Yes
TKMETMET(M1250T)met proto-oncogene (hepatocyte growth factor receptor) (MET(M1250T))Human  Yes
TKMETMET(Y1235D)met proto-oncogene (hepatocyte growth factor receptor) (MET(Y1235D))Human  Yes
STEMINK1MINKmisshapen like kinase 1 (MINK)Human  Yes
Receptor Tyrosine KinasemINSRamINSRaInsulin receptor, isoform A (INSR)MouseYesYesYes
Receptor Tyrosine KinasemINSRbmINSRbInsulin receptor, isoform B (INSR)MouseYesYesYes
STEMAP2K7MKK7mitogen-activated protein kinase kinase 7 (MKK7)Human  Yes
CAMKMKNK1MKNK1MAP kinase interacting serine/threonine kinase 1 (MKNK1)Human  Yes
CAMKMKNK2MKNK2MAP kinase interacting serine/threonine kinase 2 (MKNK2)Human  Yes
CAMKMYLK3MLCKmyosin light chain kinase 3 (MLCK)Human  Yes
TKLMAP3K9MLK1mitogen-activated protein kinase kinase kinase 9 (MLK1)Human  Yes
TKLMAP3K10MLK2mitogen-activated protein kinase kinase kinase 10 (MLK2)Human  Yes
TKLMAP3K11MLK3mitogen-activated protein kinase kinase kinase 11 (MLK3)Human  Yes
TKLMLKLMLKLmixed lineage kinase domain-like protein isoform 1 [Homo sapiens] (MLKL)Human  Yes
TKLMLKLMLKL(full-length)mixed lineage kinase domain-like protein isoform 1 [Homo sapiens] (MLKL(full-length))Human  Yes
AGCCDC42BPAMRCKACDC42 binding protein kinase alpha (DMPK-like) (MRCKA)Human  Yes
AGCCDC42BPBMRCKBCDC42 binding protein kinase beta (DMPK-like) (MRCKB)Human  Yes
STESTK4MST1serine/threonine kinase 4 (MST1)Human  Yes
TKMST1RMST1Rmacrophage stimulating 1 receptor (c-met-related tyrosine kinase) (MST1R)Human  Yes
STESTK3MST2serine/threonine kinase 3 (MST2)Human  Yes
STESTK24MST3serine/threonine kinase 24 (MST3)Human  Yes
STEMST4MST4serine/threonine protein kinase MST4 (MST4)Human  Yes
AtypicalMTORMTORmechanistic target of rapamycin (serine/threonine kinase) (MTOR)Human  Yes
TKMUSKMUSKmuscle, skeletal, receptor tyrosine kinase (MUSK)Human  Yes
CAMKMYLKMYLKmyosin light chain kinase (MYLK)Human  Yes
CAMKMYLK2MYLK2myosin light chain kinase 2 (MYLK2)Human  Yes
CAMKMYLK4MYLK4myosin light chain kinase family, member 4 (MYLK4)Human  Yes
STEMYO3AMYO3Amyosin IIIA (MYO3A)Human  Yes
STEMYO3BMYO3Bmyosin IIIB (MYO3B)Human  Yes
AGCSTK38NDR1serine/threonine kinase 38 (NDR1)Human  Yes
AGCSTK38LNDR2serine/threonine kinase 38 like (NDR2)Human  Yes
OtherNEK1NEK1NIMA (never in mitosis gene a)-related kinase 1 (NEK1)Human  Yes
OtherNEK10NEK10NIMA (never in mitosis gene a)- related kinase 10 (NEK10)Human  Yes
OtherNEK11NEK11NIMA (never in mitosis gene a)-related kinase 11 (NEK11)Human  Yes
OtherNEK2NEK2NIMA (never in mitosis gene a)-related kinase 2 (NEK2)Human  Yes
OtherNEK3NEK3NIMA (never in mitosis gene a)-related kinase 3 (NEK3)Human  Yes
OtherNEK4NEK4NIMA (never in mitosis gene a)-related kinase 4 (NEK4)Human  Yes
OtherNEK5NEK5NIMA (never in mitosis gene a)-related kinase 5 (NEK5)Human  Yes
OtherNEK6NEK6NIMA (never in mitosis gene a)-related kinase 6 (NEK6)Human  Yes
OtherNEK7NEK7NIMA (never in mitosis gene a)-related kinase 7 (NEK7)Human  Yes
OtherNEK9NEK9NIMA (never in mitosis gene a)-related kinase 9 (NEK9)Human  Yes
CAMKMGC42105NIM1serine/threonine-protein kinase NIM1 (NIM1)Human  Yes
CMGCNLKNLKnemo-like kinase (NLK)Human  Yes
STEOXSR1OSR1oxidative-stress responsive 1 (OSR1)Human  Yes
CMGCMAPK14p38-alphamitogen-activated protein kinase 14 (p38-alpha)Human  Yes
CMGCMAPK11p38-betamitogen-activated protein kinase 11 (p38-beta)Human  Yes
CMGCMAPK13p38-deltamitogen-activated protein kinase 13 (p38-delta)Human  Yes
CMGCMAPK12p38-gammamitogen-activated protein kinase 12 (p38-gamma)Human  Yes
STEPAK1PAK1p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1)Human  Yes
STEPAK2PAK2p21 protein (Cdc42/Rac)-activated kinase 2 (PAK2)Human  Yes
STEPAK3PAK3p21 protein (Cdc42/Rac)-activated kinase 3 (PAK3)Human  Yes
STEPAK4PAK4p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4)Human  Yes
STEPAK6PAK6p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6)Human  Yes
STEPAK7PAK7p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7)Human  Yes
CAMKPASKPASKPAS domain containing serine/threonine kinase [ Homo sapiens (human) ] (PASK)Human  Yes
CMGCCDK16PCTK1cyclin-dependent kinase 16 (PCTK1)Human  Yes
CMGCCDK17PCTK2cyclin-dependent kinase 17 (PCTK2)Human  Yes
CMGCCDK18PCTK3cyclin-dependent kinase 18 (PCTK3)Human  Yes
Receptor Tyrosine KinasePDGFRaPDGFRaPlatelet-derived growth factor receptor alpha (PDGFRa)HumanYesYesYes
Receptor Tyrosine KinasePDGFRBPDGFRbPlatelet-derived growth factor receptor beta (PDGFRb)HumanYesYesYes
AGCPDPK1PDPK13-phosphoinositide dependent protein kinase-1 (PDPK1)Human  Yes
PathogenCDPK1PFCDPK1(P.falciparum)Calcium-dependent protein kinase 1 (PFCDPK1(P.falciparum))P.falciparum  Yes
PathogenMAL13P1.279PFPK5(P.falciparum)Protein Kinase 5 (PFPK5(P.falciparum))P.falciparum  Yes
CMGCCDK15PFTAIRE2Cyclin-Dependent Kinase 15 (PFTAIRE2)Human  Yes
CMGCCDK14PFTK1Cyclin-Dependent Kinase 14 (PFTK1)Human  Yes
CAMKPHKG1PHKG1phosphorylase kinase, gamma 1 (muscle) (PHKG1)Human  Yes
CAMKPHKG2PHKG2phosphorylase kinase, gamma 2 (testis) (PHKG2)Human  Yes
Phosphoinositide kinasePI3KδPI3KδPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta)HumanYes Yes
LipidPIK3C2BPIK3C2Bphosphoinositide-3-kinase, class 2, beta polypeptide (PIK3C2B)Human  Yes
LipidPIK3C2GPIK3C2Gphosphoinositide-3-kinase, class 2, gamma polypeptide (PIK3C2G)Human  Yes
LipidPIK3CAPIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA)Human  Yes
LipidPIK3CAPIK3CA(C420R)phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA(C420R))Human  Yes
LipidPIK3CAPIK3CA(E542K)phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA(E542K))Human  Yes
LipidPIK3CAPIK3CA(E545A)phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA(E545A))Human  Yes
LipidPIK3CAPIK3CA(E545K)phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA(E545K))Human  Yes
LipidPIK3CAPIK3CA(H1047L)phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA(H1047L))Human  Yes
LipidPIK3CAPIK3CA(H1047Y)phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA(H1047Y))Human  Yes
LipidPIK3CAPIK3CA(I800L)phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA(I800L))Human  Yes
LipidPIK3CAPIK3CA(M1043I)phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA(M1043I))Human  Yes
LipidPIK3CAPIK3CA(Q546K)phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA(Q546K))Human  Yes
LipidPIK3CBPIK3CBphosphoinositide-3-kinase, catalytic, beta polypeptide (PIK3CB)Human  Yes
LipidPIK3CDPIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptide (PIK3CD)Human  Yes
LipidPIK3CGPIK3CGphosphoinositide-3-kinase, catalytic, gamma polypeptide (PIK3CG)Human  Yes
LipidPI4KBPIK4CBphosphatidylinositol 4-kinase, catalytic, beta (PIK4CB)Human  Yes
LipidPIKFYVEPIKFYVEphosphoinositide kinase, FYVE finger containing [ Homo sapiens (human) ] (PIKFYVE)Human  Yes
Ser/Thr KinasePIM1PIM1Pim-1 oncogene (PIM1)HumanYesYesYes
CAMKPIM2PIM2pim-2 oncogene (PIM2)Human  Yes
CAMKPIM3PIM3pim-3 oncogene (PIM3)Human  Yes
LipidPIP5K1APIP5K1Aphosphatidylinositol-4-phosphate 5-kinase, type I, alpha (PIP5K1A)Human  Yes
LipidPIP5K1CPIP5K1Cphosphatidylinositol-4-phosphate 5-kinase, type I, gamma (PIP5K1C)Human  Yes
LipidPIP4K2BPIP5K2Bphosphatidylinositol-5-phosphate 4-kinase, type II, beta (PIP5K2B)Human  Yes
LipidPIP4K2CPIP5K2Cphosphatidylinositol-5-phosphate 4-kinase, type II, gamma (PIP5K2C)Human  Yes
AGCPRKACAPKAC-alphaprotein kinase, cAMP-dependent, catalytic, alpha (PKAC-alpha)Human  Yes
AGCPRKACAPKAC-alpha(L206R)cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1 [Homo sapiens] (PKAC-alpha(L206R))Human  Yes
AGCPRKACBPKAC-betaprotein kinase, cAMP-dependent, catalytic, beta (PKAC-beta)Human  Yes
OtherPKMYT1PKMYT1protein kinase, membrane associated tyrosine/threonine 1 (PKMYT1)Human  Yes
AGCPKN1PKN1protein kinase N1 (PKN1)Human  Yes
AGCPKN2PKN2protein kinase N2 (PKN2)Human  Yes
PathogenpknBPKNB(M.tuberculosis)Transmembrane Serine/Threonine-Protein Kinase B (PKNB(M.tuberculosis))M.tuberculosis  Yes
OtherPLK1PLK1polo-like kinase 1 (PLK1)Human  Yes
OtherPLK2PLK2polo-like kinase 2 (PLK2)Human  Yes
OtherPLK3PLK3polo-like kinase 3 (PLK3)Human  Yes
OtherPLK4PLK4polo-like kinase 4 (PLK4)Human  Yes
AGCPRKCDPRKCDprotein kinase C, delta (PRKCD)Human  Yes
AGCPRKCEPRKCEprotein kinase C, epsilon (PRKCE)Human  Yes
AGCPRKCHPRKCHprotein kinase C, eta (PRKCH)Human  Yes
AGCPRKCIPRKCIprotein kinase C, iota (PRKCI)Human  Yes
AGCPRKCQPRKCQprotein kinase C, theta (PRKCQ)Human  Yes
CAMKPRKD1PRKD1protein kinase D1 (PRKD1)Human  Yes
CAMKPRKD2PRKD2protein kinase D2 (PRKD2)Human  Yes
CAMKPRKD3PRKD3protein kinase D3 (PRKD3)Human  Yes
AGCPRKG1PRKG1protein kinase, cGMP-dependent, type I (PRKG1)Human  Yes
AGCPRKG2PRKG2protein kinase, cGMP-dependent, type II (PRKG2)Human  Yes
OtherEIF2AK2PRKReukaryotic translation initiation factor 2-alpha kinase 2 (PRKR)Human  Yes
AGCPRKXPRKXprotein kinase, X-linked (PRKX)Human  Yes
Cytosolic Tyrosine KinasePRLR-JAK1PRLR-JAK1Prolactin receptor (PRLR)HumanYesYesYes
Cytosolic Tyrosine KinasePRLR-JAK2PRLR-JAK2Prolactin receptor (PRLR)HumanYesYesYes
CMGCPRPF4BPRP4pre-mRNA processing factor 4B (PRP4)Human  Yes
Protein Tyrosine KinasePYK2PYK2PTK2B protein tyrosine kinase 2 beta (PTK2B)HumanYesYesYes
CAMKKIAA0999QSKSIK family kinase 3 (QSK)Human  Yes
TKLRAF1RAF1v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1)Human  Yes
TKRETRETret proto-oncogene (RET)Human  Yes
TKRETRET(A883F)ret proto-oncogene (RET(A883F))Human  Yes
TKRETRET(M918T)ret proto-oncogene (RET(M918T))Human  Yes
TKRETRET(V804E)ret proto-oncogene (RET(V804E))Human  Yes
TKRETRET(V804L)ret proto-oncogene (RET(V804L))Human  Yes
TKRETRET(V804M)ret proto-oncogene (RET(V804M))Human  Yes
Receptor Tyrosine KinaserhTrkA-rhP75rhTrkA-rhP75Neurotrophic tyrosine kinase receptor type 1 (NTRK1)RhesusYesYesYes
AtypicalRIOK1RIOK1RIO kinase 1 (RIOK1)Human  Yes
AtypicalRIOK2RIOK2RIO kinase 2 (RIOK2)Human  Yes
AtypicalRIOK3RIOK3RIO kinase 3 (RIOK3)Human  Yes
TKLRIPK1RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 1 (RIPK1)HumanYes Yes
Ser/Thr KinaseRIPK1RIPK1Receptor (TNFRSF)-Interacting Serine-Threonine Kinase 1 (RIPK1)HumanYes Yes
Receptor Tyrosine KinaseRIPK2RIPK2Receptor-interacting serine-threonine kinase 2 (RIPK2)HumanYesYesYes
TKLRIPK3RIPK3receptor-interacting serine-threonine kinase 3 (RIPK3)HumanYes Yes
Ser/Thr KinaseRIPK3RIPK3Receptor-Interacting Serine-Threonine Kinase 3 (RIPK3)HumanYes Yes
TKLRIPK4RIPK4receptor-interacting serine-threonine kinase 4 (RIPK4)Human  Yes
OtherDSTYKRIPK5dual serine/threonine and tyrosine protein kinase (RIPK5)Human  Yes
AGCROCK1ROCK1Rho-associated, coiled-coil containing protein kinase 1 (ROCK1)Human  Yes
AGCROCK2ROCK2Rho-associated, coiled-coil containing protein kinase 2 (ROCK2)Human  Yes
TKROS1ROS1c-ros oncogene 1 , receptor tyrosine kinase (ROS1)Human  Yes
AGCRPS6KA4RPS6KA4(Kin.Dom.1-N-terminal)ribosomal protein S6 kinase, 90kDa, polypeptide 4 (RPS6KA4(Kin.Dom.1-N-terminal))Human  Yes
CAMKRPS6KA4RPS6KA4(Kin.Dom.2-C-terminal)ribosomal protein S6 kinase, 90kDa, polypeptide 4 (RPS6KA4(Kin.Dom.2-C-terminal))Human  Yes
AGCRPS6KA5RPS6KA5(Kin.Dom.1-N-terminal)ribosomal protein S6 kinase, 90kDa, polypeptide 5 (RPS6KA5(Kin.Dom.1-N-terminal))Human  Yes
CAMKRPS6KA5RPS6KA5(Kin.Dom.2-C-terminal)ribosomal protein S6 kinase, 90kDa, polypeptide 5 (RPS6KA5(Kin.Dom.2-C-terminal))Human  Yes
AGCRPS6KA1RSK1(Kin.Dom.1-N-terminal)ribosomal protein S6 kinase, 90kDa, polypeptide 1 (RSK1(Kin.Dom.1-N-terminal))Human  Yes
CAMKRPS6KA1RSK1(Kin.Dom.2-C-terminal)ribosomal protein S6 kinase, 90kDa, polypeptide 1 (RSK1(Kin.Dom.2-C-terminal))Human  Yes
AGCRPS6KA3RSK2(Kin.Dom.1-N-terminal)ribosomal protein S6 kinase, 90kDa, polypeptide 3 (RSK2(Kin.Dom.1-N-terminal))Human  Yes
CAMKRPS6KA3RSK2(Kin.Dom.2-C-terminal)ribosomal protein S6 kinase alpha-3 (RSK2(Kin.Dom.2-C-terminal))Human  Yes
AGCRPS6KA2RSK3(Kin.Dom.1-N-terminal)ribosomal protein S6 kinase, 90kDa, polypeptide 2 (RSK3(Kin.Dom.1-N-terminal))Human  Yes
CAMKRPS6KA2RSK3(Kin.Dom.2-C-terminal)ribosomal protein S6 kinase, 90kDa, polypeptide 2 (RSK3(Kin.Dom.2-C-terminal))Human  Yes
AGCRPS6KA6RSK4(Kin.Dom.1-N-terminal)ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RSK4(Kin.Dom.1-N-terminal))Human  Yes
CAMKRPS6KA6RSK4(Kin.Dom.2-C-terminal)ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RSK4(Kin.Dom.2-C-terminal))Human  Yes
Receptor Tyrosine KinaserTrkA-rP75rTrkA-rP75Neurotrophic tyrosine kinase receptor type 1 (NTRK1)RatYes Yes
AGCRPS6KB1S6K1ribosomal protein S6 kinase, 70kDa, polypeptide 1 (S6K1)Human  Yes
OtherSBK1SBK1SH3-binding domain kinase 1 (SBK1)Human  Yes
AGCSGK1SGKserum/glucocorticoid regulated kinase 1 (SGK)Human  Yes
OtherSgK110SgK110Putative uncharacterized serine/threonine-protein kinase (Sugen kinase 110) (SgK110)Human  Yes
AGCSGK2SGK2serum/glucocorticoid regulated kinase 2 (SGK2)Human  Yes
AGCSGK3SGK3serum/glucocorticoid regulated kinase family, member 3 (SGK3)Human  Yes
CAMKSIK1SIKsalt-inducible kinase 1 (SIK)Human  Yes
Ser/Thr KinaseSIK1SIK1Salt-inducible kinase 1 (SIK1)HumanYesYesYes
CAMKSIK2SIK2salt-inducible kinase 2 (SIK2)Human  Yes
STESLKSLK STE20 like kinase (SLK)Human  Yes
CAMKNUAK2SNARKNUAK family, SNF1-like kinase, 2 (SNARK)Human  Yes
CAMKSNRKSNRKSNF related kinase (SNRK)Human  Yes
TKSRCSRCSRC proto-oncogene, non-receptor tyrosine kinaseHuman  Yes
TKSRMSSRMSsrc-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites (SRMS)Human  Yes
CMGCSRPK1SRPK1SFRS protein kinase 1 (SRPK1)Human  Yes
CMGCSRPK2SRPK2SFRS protein kinase 2 (SRPK2)Human  Yes
CMGCSRPK3SRPK3SFRS protein kinase 3 (SRPK3)Human  Yes
OtherSTK16STK16serine/threonine kinase 16 (STK16)Human  Yes
CAMKSTK33STK33serine/threonine kinase 33 (STK33)Human  Yes
OtherSTK35STK35serine/threonine kinase 35 (STK35)Human  Yes
OtherSTK36STK36serine/threonine kinase 36 (STK36)Human  Yes
STESTK39STK39serine/threonine kinase 39 (STK39)Human  Yes
Cytosolic tyrosine kinaseSYKSYKSpleen tyrosine kinase (SYK)HumanYesYesYes
TKLMAP3K7TAK1mitogen-activated protein kinase kinase kinase 7 (TAK1)Human  Yes
STETAOK1TAOK1TAO kinase 1 (TAOK1)Human  Yes
STETAOK2TAOK2TAO kinase 2 (TAOK2)Human  Yes
STETAOK3TAOK3TAO kinase 3 (TAOK3)Human  Yes
OtherTBK1TBK1TANK-binding kinase 1 (TBK1)Human  Yes
TKTECTECtec protein tyrosine kinase (TEC)Human  Yes
TKLTESK1TESK1testis-specific kinase 1 (TESK1)Human  Yes
TKLTGFBR1TGFBR1transforming growth factor, beta receptor 1 (TGFBR1)Human  Yes
Ser/Thr KinaseTGFBR1/ACVR2TGFBR1/ACVR2Transforming growth factor, beta receptor 1 (TGFBR1)HumanYesYes 
Ser/Thr KinaseTGFBR1/ACVR2BTGFBR1/ACVR2BTransforming growth factor, beta receptor 1 (TGFBR1)HumanYesYes 
Ser/Thr KinaseTGFBR1/TGFBR2TGFBR1/TGFBR2Transforming growth factor, beta receptor 1 (TGFBR1)HumanYesYes 
TKLTGFBR2TGFBR2transforming growth factor, beta receptor II (70/80kDa) (TGFBR2)Human  Yes
TKTIE1TIE1tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (TIE1)Human  Yes
TKTEKTIE2TEK tyrosine kinase, endothelial (TIE2)HumanYes Yes
Receptor Tyrosine KinaseTie2Tie2Angiopoietin-1 receptor (Tie2)HumanYes Yes
OtherTLK1TLK1tousled-like kinase 1 (TLK1)Human  Yes
OtherTLK2TLK2tousled-like kinase 2 (TLK2)Human  Yes
STETNIKTNIKTRAF2 and NCK interacting kinase (TNIK)Human  Yes
TKTNK1TNK1tyrosine kinase, non-receptor, 1 (TNK1)Human  Yes
TKTNK2TNK2tyrosine kinase, non-receptor, 2 (TNK2)Human  Yes
TKLTNNI3KTNNI3KTNNI3 interacting kinase (TNNI3K)Human  Yes
Receptor Tyrosine KinaseTrkATrkANeurotrophic tyrosine kinase receptor type 1 (NTRK1)HumanYesYesYes
Receptor Tyrosine KinaseTrkA-P75TrkA-P75Neurotrophic tyrosine kinase receptor type 1 (NTRK1)HumanYesYesYes
Receptor Tyrosine KinaseTrkBTrkBNeurotrophic tyrosine kinase receptor type 2 (NTRK2)HumanYesYesYes
Receptor Tyrosine KinaseTrkB-P75TrkB-P75Neurotrophic tyrosine kinase receptor type 2 (NTRK2)HumanYesYesYes
Receptor Tyrosine KinaseTrkCTrkCNeurotrophic tyrosine kinase receptor type 3 (NTRK3)HumanYesYesYes
Receptor Tyrosine KinaseTrkC-P75TrkC-P75Neurotrophic tyrosine kinase receptor type 3 (NTRK3)HumanYesYesYes
AtypicalTRPM6TRPM6transient receptor potential cation channel, subfamily M, member 6 (TRPM6)Human  Yes
CAMKTSSK1BTSSK1Btestis-specific serine kinase 1B (TSSK1B)Human  Yes
CAMKTSSK3TSSK3testis-specific serine/threonine-protein kinase 3 (TSSK3)Human  Yes
OtherTTKTTKTTK protein kinase (TTK)Human  Yes
TKTXKTXKTXK tyrosine kinase (TXK)Human  Yes
Cytosolic tyrosine kinaseTYK2TYK2Tyrosine kinase 2 (TYK2)HumanYesYesYes
TKTYK2TYK2(JH1domain-catalytic)tyrosine kinase 2 (TYK2(JH1domain-catalytic))Human  Yes
TKTYK2TYK2(JH2domain-pseudokinase)tyrosine kinase 2 (TYK2(JH2domain-pseudokinase))Human  Yes
TKTYRO3TYRO3TYRO3 protein tyrosine kinase (TYRO3)Human  Yes
OtherULK1ULK1unc-51-like kinase 1 (ULK1)Human  Yes
OtherULK2ULK2unc-51-like kinase 2 (ULK2)Human  Yes
OtherULK3ULK3unc-51-like kinase 3 (ULK3)Human  Yes
TKKDRVEGFR2kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGFR2)Human  Yes
LipidPIK3C3VPS34phosphatidylinositol 3-kinase, catalytic subunit type 3 (VPS34)Human  Yes
CK1VRK2VRK2vaccinia related kinase 2 (VRK2)Human  Yes
OtherWEE1WEE1WEE1 G2 checkpoint kinase (WEE1)Human  Yes
OtherWEE2WEE2WEE1 homolog 2 (WEE2)Human  Yes
OtherWNK1WNK1WNK lysine deficient protein kinase 1 (WNK1)Human  Yes
OtherWNK2WNK2WNK lysine deficient protein kinase 2 (WNK2)Human  Yes
OtherWNK3WNK3WNK lysine deficient protein kinase 3 (WNK3)Human  Yes
OtherWNK4WNK4WNK lysine deficient protein kinase 4 (WNK4)Human  Yes
AGCSTK32AYANK1serine/threonine kinase 32A (YANK1)Human  Yes
AGCSTK32BYANK2serine/threonine kinase 32B (YANK2)Human  Yes
AGCSTK32CYANK3serine/threonine kinase 32C (YANK3)Human  Yes
TKYES1YESv-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (YES)Human  Yes
Cytosolic tyrosine kinaseYES1YES1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (YES)HumanYesYesYes
STESTK25YSK1serine/threonine kinase 25 (YSK1)Human  Yes
STEMAP3K19YSK4mitogen-activated protein kinase kinase kinase 19 (YSK4)Human  Yes
TKLZAKZAKsterile alpha motif and leucine zipper containing kinase AZK (ZAK)Human  Yes
TKZAP70ZAP70zeta-chain (TCR) associated protein kinase 70kDa (ZAP70)Human  Yes
+

Epigenetic Target List

View our complete list of Epigenetic Targets
FamilyGene Symbol ▲Common NameSpeciesCell LinesAssay Ready KitsService
BromoDomainATAD2AATPase family AAA domain-containing protein 2 (ATAD2A)human  Yes
BromoDomainATAD2BATPase family, AAA domain containing 2B (ATAD2B)human  Yes
BromodomainATAD2BATPase family AAA domain containing, 2B (ATAD2B)Human  Yes
BromodomainBAZ1Abromodomain adjacent to zinc finger domain, 1A (BAZ1A)Human   
BromodomainBAZ1Bbromodomain adjacent to zinc finger domain, 1B (BAZ1B)Human   
BromoDomainBAZ2Abromodomain adjacent to zinc finger domain, 2A (BAZ2A)humanYes Yes
BromodomainBAZ2Abromodomain adjacent to zinc finger domain, 2A (BAZ2A)HumanYes Yes
BromoDomainBAZ2Bbromodomain adjacent to zinc finger domain, 2B (BAZ2B)human  Yes
BromoDomainBRD1bromodomain-containing protein 1 (BRD1)human  Yes
BromodomainBrd2(1)Bromodomain containing protein 2, 1st bromodomain (BRD2)HumanYesYesYes
BromodomainBRD2(1,2)Bromodomain containing protein 2, 1st & 2nd bromodomains (BRD2)HumanYes Yes
BromoDomainBRD2(2)bromodomain-containing protein 2 isoform 1, bromodomain 2 (BRD2(2))human  Yes
BromoDomainBRD3(1)bromodomain-containing protein 3, bromodomain 1 (BRD3(1))humanYes Yes
BromodomainBRD3(1)Bromodomain-containing protein 3, 1st bromodomain (BRD3)HumanYes Yes
BromodomainBRD3(1,2)Bromodomain-containing protein 3, 1st & 2nd bromodomains (BRD3)HumanYesYesYes
BromoDomainBRD3(2)bromodomain-containing protein 3, bromodomain 2 (BRD3(2))human  Yes
BromodomainBrd4(1)Bromodomain containing protein 4, 1st bromodomain (BRD4)HumanYesYesYes
BromoDomainBRD4(1,2)bromodomain-containing protein 4 isoform long, bromodomains 1 and 2 (BRD4(1,2))human  Yes
BromoDomainBRD4(2)bromodomain-containing protein 4 isoform long, bromodomain 2 (BRD4(2))human  Yes
BromoDomainBRD4(full-length,short-iso.)bromodomain-containing protein 4 isoform short (BRD4(full-length,short-iso.))human  Yes
BromodomainBrd7Bromodomain containing protein 7 (BRD7)Human  Yes
BromoDomainBRD8(1)bromodomain containing 8, bromodomain 1 (BRD8(1))human  Yes
BromoDomainBRD8(2)bromodomain containing 8, bromodomain 2 (BRD8(2))human  Yes
BromoDomainBRD9bromodomain-containing protein 9 isoform 1 (BRD9)human  Yes
BromodomainBrdT(1)Bromodomain containing testis-specific, 1st bromodomain (BRDT)HumanYes Yes
BromodomainBRDT(1,2)Bromodomain containing testis-specific, 1st & 2nd bromodomains (BRDT)HumanYesYesYes
BromoDomainBRDT(2)bromodomain testis-specific protein isoform b, bromodomain 2 (BRDT(2))human  Yes
BromoDomainBRPF1bromodomain and PHD finger containing, 1 (BRPF1)human  Yes
BromoDomainBRPF3bromodomain and PHD finger containing, 3 (BRPF3)human  Yes
BromodomainBRPF3bromodomain and PHD finger containing, 3 (BRPF3)Human  Yes
BromodomainBRWD3(2)Bromodomain and WD repeat-containing 3, 2nd bromodomain (BRWD3(2))Human   
BromodomainCECR2Cat eye syndrome critical region protein 2 (CECR2)Human  Yes
BromoDomainCREBBPCREB binding protein (CREBBP)human  Yes
BromoDomainEP300E1A binding protein p300 (EP300)humanYes Yes
BromodomainEP300EP300 (EP300)HumanYes Yes
BromoDomainFALZnucleosome-remodeling factor subunit BPTF isoform 1 (FALZ)human  Yes
BromodomainFALZNucleosome-remodeling factor subunit BPT (FALZ)Human  Yes
Histone methyltransferaseG9aEuchromatic histone-lysine N-methyltransferase 2 (EHMT2)HumanYesYesYes
BromodomainGCN5L2Histone Acetyltransferase, KAT2A (GCN5L2)Human  Yes
Histone methyltransferaseGLPEuchromatic histone-lysine N-methyltransferase 1 (EHMT1)HumanYesYesYes
BromodomainMLLHistone-lysine N-methyltransferase MLL (MLL)Human   
BromodomainPB1(1)Polybromo 1, 1st bromodomain (PB1(1))Human   
BromodomainPB1(2)Polybromo 1, 2nd bromodomain (PB1(2))Human   
BromoDomainPBRM1(2)polybromo 1, bromodomain 2 (PBRM1(2))human  Yes
BromoDomainPBRM1(5)polybromo 1, bromodomain 5 (PBRM1(5))human  Yes
BromodomainPCAFHistone acetyltransferase KAT2B (PCAF)Human  Yes
BromodomainPHIP(1)PH-interacting protein, 1st bromodomain (PHIP(1))Human   
BromodomainPHIP(2)PH-interacting protein, 2nd bromodomain (PHIP(2))Human   
BromodomainPRKCBP1Protein kinase C-binding protein 1 (PRKCBP1)Human   
Histone methyltransferasePRMT3Protein arginine N-methyltransferase 3 (PRMT3)HumanYes Yes
BromoDomainSMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2)human  Yes
BromoDomainSMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4)humanYesYesYes
BromodomainSP110Nuclear body protein, SP110 (SP110)Human   
BromodomainSP140Nuclear body protein, SP140 (SP140)Human   
BromodomainTAF1(1,2)Transcription initiation factor TFIID subunit 1 (TAF1(1,2))Human   
BromoDomainTAF1(2)TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa, bromodomain 2 (TAF1(2))human  Yes
BromodomainTAF1L(1)Transcription initiation factor TFIID subunit 1-like, 1st bromodomain (TAF1L(1))Human   
BromodomainTAF1L(2)Transcription initiation factor TFIID subunit 1-like, 2nd bromodomain (TAF1L(2))HumanYes Yes
BromoDomainTRIM24(Bromo.)tripartite motif containing 24 (TRIM24(Bromo.))human  Yes
BromoDomainTRIM24(PHD,Bromo.)tripartite motif containing 24 (TRIM24(PHD,Bromo.))human  Yes
BromodomainTRIM33E3 ubiquitin-protein ligase TRIM33 (TRIM33)Human   
BromoDomainTRIM33(PHD,Bromo.)tripartite motif containing 33 (TRIM33(PHD,Bromo.))human  Yes
BromodomainWDR9(1)WD repeat 9, 1st bromodomain (WDR9(1))Human   
BromodomainWDR9(2)WD repeat 9, 2nd bromodomain (WDR9(2))Human  Yes
+

NHR Target List

View our complete list of NHR Targets
Gene Symbol ▲Common NameSpeciesEntrez Gene SymbolCell LinesAssay Ready KitsService
ARAndrogen receptor (AR)HumanARYesYesYes
ERRαEstrogen related receptor alpha (ESRRA)HumanERRαYesYes 
ERαEstrogen receptor 1 (ESR1)HumanERαYes Yes
FXRNuclear receptor subfamily 1, group H, member 4 (NR1H4)HumanFXRYesYesYes
GRNuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1)HumanGRYesYesYes
LXRαNuclear receptor subfamily 1, group H, member 3 (Liver X receptor α) (NR1H3)HumanLXRαYesYesYes
LXRβNuclear receptor subfamily 1, group H, member 2 (Liver X receptor β) (NR1H2)HumanLXRβYesYesYes
LXRβ-NCoR1Nuclear receptor subfamily 1, group H, member 2 (Liver X receptor β) (NR1H2)HumanLXRβ-NCoR1Yes Yes
MRNuclear receptor subfamily 3, group C, member 2 (Mineralcorticoid receptor) (NR3C2)HumanMRYesYesYes
PPARαPeroxisome Proliferator Activated Receptor alpha (PPARA)HumanPPARαYesYesYes
PPARγPeroxisome Proliferator Activated Receptor gamma (PPARG)HumanPPARγYesYesYes
PPARδPeroxisome Proliferator Activated Receptor delta (PPARD)HumanPPARδYes Yes
PRαProgesterone receptor α (PGR)HumanPRαYesYesYes
PRβProgesterone receptor β (PGR)HumanPRβYesYesYes
RARαRetinoic acid receptor, alpha (RARA)HumanRARαYes Yes
RARβRetinoic acid receptor, beta (RARB)HumanRARβYes Yes
RXRαRetinoid X receptor, alpha (RXRA)HumanRXRαYes Yes
RXRγRetinoid X receptor, gamma (RXRG)HumanRXRγYes Yes
THRαThyroid hormone receptor, alpha (THRA)HumanTHRαYesYesYes
THRβThyroid hormone receptor, beta (THRB)HumanTHRβYesYesYes
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Pathway Target List

View our complete list of Pathway Assay Targets
Target / Description ▲Common NameFamilySpeciesCell LinesAssay Ready KitsService
CDC25ACell division cycle 25 homolog A (CDC25A)Cell Cycle ProteinHumanYesYesYes
FOXO3forkhead box O3 (forkhead box O3)PathwayHumanYesYesYes
IκBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA)PathwayHumanYesYesYes
Keap1-NRF2nuclear factor (erythroid-derived 2)-like 2 (NFE2L2)Transcription FactorHumanYesYesYes
NPR1Natriuretic peptide receptor A (NPR1)Guanylate Cyclase AHumanYes Yes
P53P53 (P53)Nuclear TranslocationHumanYes Yes
RANK-IκBTumor necrosis factor receptor superfamily, member 11a (TNFRSF11A)Tumor Necrosis Factor Receptor SuperfamilyHumanYes Yes
RELA-IκBv-rel reticuloendotheliosis viral oncogene homolog A (avian) (RELA)Transcription factorHumanYesYesYes
SREBP2Sterol regulatory element binding transcription factor 2 (SREBF2)Transcription FactorHumanYesYesYes
TNFαTumor necrosis factor alpha (TNFα)NFkBHuman   
TORC1CREB regulated transcription coactivator 1 (CRTC1)Transcription factorHumanYesYesYes
TORC2CREB regulated transcription coactivator 2 (CRTC2)Transcription factorHumanYesYesYes
XBP1X-box binding protein 1 (XBP1)Transcription factorHumanYesYesYes
β-CateninCatenin (cadherin-associated protein), beta 1 (CTNNB1)Wnt-Frizzled signallingHumanYesYesYes
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