Cytotoxicity Product Solutions
Functional, MOA-reflective cell-based cytotoxicity assays to detect target cell death across various applications including ADCC, ADCP, CDC, CAR-T, an...Show More
Pharmacotrafficking Assays
Quantitative cell-based assays for the identification of pharmacochaperones that rescue misfolded membrane proteins involved in mutation diseases.
Potency, Commercial Release & Stability
Qualified, MOA-reflective cell-based assays that are phase-appropriate & provide superior lot-to-lot reproducibility for potency & QC lot-release test...Show More
Translocation Assays
Screening cell-based translocation assays for analyzing the movement of proteins to multiple membrane compartments within the cell
Signaling Reporters
Signaling reporter assays are functional, cell-based assays with a downstream read-out for screening molecules based on ligand activation or inhibitio...Show More
Target Engagement Assays
InCELL target engagement assays assess compound cell entry & protein target binding, & screen & rank inhibitors all in the native cellular environment
Targeted Protein Degradation
Targeted protein degradation assays to rapidly screen small molecules that trigger protein degradation, & to quantify endogenous protein turnover.
Bioassays for Cytotoxicity Applications
Robust, reproducible, and ready-to-use MOA-based bioassays to measure direct cell death and evaluate the cytotoxicity of your clinical antibody candid...Show More
GPCR Internalization Assays
GPCR internalization assays are functional, cell-based assays that measure GPCR endocytosis in live cells without a microscope, imaging or antibodies.
Effector Cells - CD16
KILR CD16 effector cells are single donor-derived human primary cells for ADCC & T-Cell redirection mediated target cell death for immunotherapeutics.