ASK1, active

N-terminal GST and C-terminal 6His-tagged recombinant, human ASK1 amino acids 649-946.

Catalog #: 14-606

$399.00$2,989.00


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Biological Information
Background Information:
Apoptosis signal-regulating kinase 1 (ASK1) is a serine/threonine protein kinase and identified as a MAPKKK which activates the c-Jun N-terminal kinase (JNK) and p38 MAP kinase pathways and is required for TNFalpha;-induced apoptosis. ASK1 suggests possible mechanisms for redox regulation of the apoptosis signal transduction pathway as well as the effects of antioxidants against cytokine- and stress-induced apoptosis. GenBank NM_005923
Target Class:
Kinase
Accession Number:
NM_005923.3
Target Name:
Ask1
Target Aliases:
MAP3K5, MEKK5, ASK1, ASK-1, MAPKKK5
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-606x Datasheet

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