GRK2, active

N-terminal 6His-tagged recombinant, human full length GRK2.

Catalog #: 14-965

$399.00$2,989.00


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Biological Information
Background Information:
GRK2 phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. GenBank NM_001619.3
Target Class:
Kinase
Accession Number:
NM_001619.3
Target Name:
RK2
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
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Datasheets

14-965x Datasheet

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