Biological Information | |
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Background Information: | Homeodomain-interacting protein kinase 3 (HIPK3), a serine/threonine kinase, has been described as a member of a family of nuclear kinases that act as co-repressors for homeodomain transcription factors. HIPK3 can activate p53-mediated transcriptional regulation of MDM2 and antagonize Myc/Ras-induced transformation. HIPK3 may play an important role in the regulation of p53 apoptotic function. Inhibition of HIPK3 may inhibit apoptosis and facilitate tumorigenesis.
GenBank NM_005734 |
Target Class: | Kinase |
Accession Number: | NM_001048200.1; NM_005734.3 |
Target Name: | HIPK3 |
Target Aliases: | HIPK3, FIST, DYRK6, ANPK, PKY, YAK1, FIST3 |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
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Datasheets
14-680x Datasheet
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