HIPK3, active

N-terminal 6His-tagged recombinant, human HIPK3 amino acids 161-562.

Catalog #: 14-680

$399.00$2,989.00


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Biological Information
Background Information:
Homeodomain-interacting protein kinase 3 (HIPK3), a serine/threonine kinase, has been described as a member of a family of nuclear kinases that act as co-repressors for homeodomain transcription factors. HIPK3 can activate p53-mediated transcriptional regulation of MDM2 and antagonize Myc/Ras-induced transformation. HIPK3 may play an important role in the regulation of p53 apoptotic function. Inhibition of HIPK3 may inhibit apoptosis and facilitate tumorigenesis. GenBank NM_005734
Target Class:
Kinase
Accession Number:
NM_001048200.1; NM_005734.3
Target Name:
HIPK3
Target Aliases:
HIPK3, FIST, DYRK6, ANPK, PKY, YAK1, FIST3
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-680x Datasheet

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