LOK, active

N-terminal 6His-tagged recombinant, human LOK amino acids 1-348.

Catalog #: 14-686

$399.00$2,989.00


Inquire
Biological Information
Background Information:
LOK, also known as STK10 (Serine/Threonine Kinase 10), a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like Kinase kinases. LOK can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. LOK can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein Kinase kinase 1 pathway. GenBank NM_005990
Target Class:
Kinase
Accession Number:
NM_005990.3
Target Name:
LOK
Target Aliases:
STK10, PRO2729, LOK
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
Usage Disclaimer:
These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Datasheets

14-686x Datasheet

View Document