Search results: “Mer”

Ready-to-use kits for early discovery phases for screening, proof-of-concept, MOA confirmation, or rank-ordering studies

Cell-based assays to measure 2nd messengers (cAMP & calcium), β-arrestin recruitment, receptor internalization, & ligand binding for GPCR targets-based drug…

Fluorescent assays to measure calcium mobilization in cell lines as a direct indication of GPCR or ion channel activation or…

Accurately monitor GPCR activation by biologics or small molecules & detect cellular cAMP production levels for a variety of applications

Universal G-protein independent cell-based assays to quantify GPCR activation based on the recruitment of β-arrestin

High-quality Ion Channel Products for Target Discovery, Hit Screening, Lead Optimization, & Safety Studies

Single donor-derived human primary cells to drive robust & reproducible ADCC & T-cell redirection

Enzymes & cell-based functional, binding, & activity assays for kinase targets discovery through development & for QC lot-release testing

Assays to interrogate the MOA of GLP-1, GIP, and GCG receptors targeting therapeutics to accelerate obesity and type-2 diabetes drug…

Accelerate cancer immunotherapeutic discovery & development with cell-based, clinically relevant assays

Quantitative cell-based assays to identify pharmacochaperones that stabilize & correct disease-relevant mutant GPCRs, ion channels, or transporters

Providing functional, MOA-based bioassays with superior lot-to-lot reproducibility & potency testing